메뉴 건너뛰기




Volumn 25, Issue 2, 2015, Pages 138-148

Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma

Author keywords

Aldehyde dehydrogenase; Chemotherapy; Dacarbazine; Diethylaminobenzaldehyde; Disulfiram; Melanoma; Metastasis

Indexed keywords

ALDEHYDE DEHYDROGENASE INHIBITOR; ALDEHYDE DEHYDROGENASE ISOENZYME 1; DACARBAZINE; DIETHYLAMINOBENZALDEHYDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; ISOENZYME; RETINAL DEHYDROGENASE;

EID: 84924953310     PISSN: 09608931     EISSN: 14735636     Source Type: Journal    
DOI: 10.1097/CMR.0000000000000144     Document Type: Article
Times cited : (53)

References (42)
  • 1
    • 0033989205 scopus 로고    scopus 로고
    • Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
    • Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S, et al. Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol 2000; 18:158-166.
    • (2000) J Clin Oncol , vol.18 , pp. 158-166
    • Middleton, M.R.1    Grob, J.J.2    Aaronson, N.3    Fierlbeck, G.4    Tilgen, W.5    Seiter, S.6
  • 3
    • 84864285704 scopus 로고    scopus 로고
    • Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
    • Hauschild A, Grob JJ, Demidov LV, Jouary T, Gutzmer R, Millward M, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 2012; 380:358-365.
    • (2012) Lancet , vol.380 , pp. 358-365
    • Hauschild, A.1    Grob, J.J.2    Demidov, L.V.3    Jouary, T.4    Gutzmer, R.5    Millward, M.6
  • 4
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
    • Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 1999; 17:2105-2116.
    • (1999) J Clin Oncol , vol.17 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3    Fisher, R.I.4    Weiss, G.5    Margolin, K.6
  • 5
    • 0033848628 scopus 로고    scopus 로고
    • High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update
    • Atkins MB, Kunkel L, Sznol M, Rosenberg SA. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am 2000; 6 (Suppl 1):S11-S14.
    • (2000) Cancer J Sci Am , vol.6 , pp. S11-S14
    • Atkins, M.B.1    Kunkel, L.2    Sznol, M.3    Rosenberg, S.A.4
  • 7
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364:2517-2526.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.4    Weber, J.5    Garbe, C.6
  • 8
    • 34250732230 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential
    • Cheung AM, Wan TS, Leung JC, Chan LY, Huang H, Kwong YL, et al. Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential. Leukemia 2007; 21:1423-1430.
    • (2007) Leukemia , vol.21 , pp. 1423-1430
    • Cheung, A.M.1    Wan, T.S.2    Leung, J.C.3    Chan, L.Y.4    Huang, H.5    Kwong, Y.L.6
  • 9
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007; 1:555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3    Monville, F.4    Dutcher, J.5    Brown, M.6
  • 10
    • 49149107236 scopus 로고    scopus 로고
    • Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
    • Dylla SJ, Beviglia L, Park IK, Chartier C, Raval J, Ngan L, et al. Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS One 2008; 3:e2428.
    • (2008) PLoS One , vol.3 , pp. e2428
    • Dylla, S.J.1    Beviglia, L.2    Park, I.K.3    Chartier, C.4    Raval, J.5    Ngan, L.6
  • 11
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 2009; 69:3382-3389.
    • (2009) Cancer Res , vol.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3    Ginestier, C.4    Dontu, G.5    Appelman, H.6
  • 13
    • 77749292153 scopus 로고    scopus 로고
    • Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma
    • Rasheed ZA, Yang J, Wang Q, Kowalski J, Freed I, Murter C, et al. Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma. J Natl Cancer Inst 2010; 102:340-351.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 340-351
    • Rasheed, Z.A.1    Yang, J.2    Wang, Q.3    Kowalski, J.4    Freed, I.5    Murter, C.6
  • 14
    • 77953789724 scopus 로고    scopus 로고
    • High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer
    • Van den Hoogen C, van der Horst G, Cheung H, Buijs JT, Lippitt JM, Guzmán-Ramírez N, et al. High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer. Cancer Res 2010; 70:5163-5173.
    • (2010) Cancer Res , vol.70 , pp. 5163-5173
    • Van Den Hoogen, C.1    Van Der Horst, G.2    Cheung, H.3    Buijs, J.T.4    Lippitt, J.M.5    Guzmán-Ramírez, N.6
  • 16
    • 84866671365 scopus 로고    scopus 로고
    • ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets
    • Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, et al. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells 2012; 30:2100-2113.
    • (2012) Stem Cells , vol.30 , pp. 2100-2113
    • Luo, Y.1    Dallaglio, K.2    Chen, Y.3    Robinson, W.A.4    Robinson, S.E.5    McCarter, M.D.6
  • 17
    • 84865316843 scopus 로고    scopus 로고
    • Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells
    • Santini R, Vinci MC, Pandolfi S, Penachioni JY, Montagnani V, Olivito B, et al. Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells. Stem Cells 2012; 30:1808-1818.
    • (2012) Stem Cells , vol.30 , pp. 1808-1818
    • Santini, R.1    Vinci, M.C.2    Pandolfi, S.3    Penachioni, J.Y.4    Montagnani, V.5    Olivito, B.6
  • 18
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer
    • Magni M, Shammah S, Schiró R, Mellado W, Dalla-Favera R, Gianni AM. Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer. Blood 1996; 87:1097-1103.
    • (1996) Blood , vol.87 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiró, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 19
    • 33749680959 scopus 로고    scopus 로고
    • Comparative proteomic analysis of cisplatin sensitive IGROV1 ovarian carcinoma cell line and its resistant counterpart IGROV1-R10
    • Le Moguen K, Lincet H, Deslandes E, Hubert-Roux M, Lange C, Poulain L, et al. Comparative proteomic analysis of cisplatin sensitive IGROV1 ovarian carcinoma cell line and its resistant counterpart IGROV1-R10. Proteomics 2006; 6:5183-5192.
    • (2006) Proteomics , vol.6 , pp. 5183-5192
    • Le Moguen, K.1    Lincet, H.2    Deslandes, E.3    Hubert-Roux, M.4    Lange, C.5    Poulain, L.6
  • 20
    • 11844285668 scopus 로고    scopus 로고
    • Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde
    • Moreb JS, Gabr A, Vartikar GR, Gowda S, Zucali JR, Mohuczy D. Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde. J Pharmacol Exp Ther 2005; 312:339-345.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 339-345
    • Moreb, J.S.1    Gabr, A.2    Vartikar, G.R.3    Gowda, S.4    Zucali, J.R.5    Mohuczy, D.6
  • 21
    • 0036202207 scopus 로고    scopus 로고
    • Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: A retrospective study. Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens
    • Sládek NE, Kollander R, Sreerama L, Kiang DT. Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study. Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens. Cancer Chemother Pharmacol 2002; 49:309-321.
    • (2002) Cancer Chemother Pharmacol , vol.49 , pp. 309-321
    • Sládek, N.E.1    Kollander, R.2    Sreerama, L.3    Kiang, D.T.4
  • 22
    • 0034985885 scopus 로고    scopus 로고
    • Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene
    • Takebe N, Zhao SC, Adhikari D, Mineishi S, Sadelain M, Hilton J, et al. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene. Mol Ther 2001; 3:88-96.
    • (2001) Mol Ther , vol.3 , pp. 88-96
    • Takebe, N.1    Zhao, S.C.2    Adhikari, D.3    Mineishi, S.4    Sadelain, M.5    Hilton, J.6
  • 23
    • 0031020655 scopus 로고    scopus 로고
    • All-trans, 13-cis and 9-cis retinoic acids induce a fully reversible growth inhibition in HNSCC cell lines: Implications for in vivo retinoic acid use
    • Giannini F, Maestro R, Vukosavljevic T, Pomponi F, Boiocchi M. All-trans, 13-cis and 9-cis retinoic acids induce a fully reversible growth inhibition in HNSCC cell lines: implications for in vivo retinoic acid use. Int J Cancer 1997; 70:194-200.
    • (1997) Int J Cancer , vol.70 , pp. 194-200
    • Giannini, F.1    Maestro, R.2    Vukosavljevic, T.3    Pomponi, F.4    Boiocchi, M.5
  • 24
    • 33745686030 scopus 로고    scopus 로고
    • Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy
    • Sabharwal A, Middleton MR. Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy. Curr Opin Pharmacol 2006; 6:355-363.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 355-363
    • Sabharwal, A.1    Middleton, M.R.2
  • 25
    • 3042842755 scopus 로고    scopus 로고
    • How retinoids regulate breast cancer cell proliferation and apoptosis
    • Simeone A-M, Tari AM. How retinoids regulate breast cancer cell proliferation and apoptosis. Cell Mol Life Sci 2004; 61:1475-1484.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 1475-1484
    • Simeone, A.-M.1    Tari, A.M.2
  • 26
    • 84930474801 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase inhibitors: A comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application
    • Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, et al. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacol Rev 2012; 64:520-539.
    • (2012) Pharmacol Rev , vol.64 , pp. 520-539
    • Koppaka, V.1    Thompson, D.C.2    Chen, Y.3    Ellermann, M.4    Nicolaou, K.C.5    Juvonen, R.O.6
  • 27
    • 0026439016 scopus 로고
    • A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites
    • Johansson B. A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites. Acta Psychiatr Scand Suppl 1992; 369:15-26.
    • (1992) Acta Psychiatr Scand Suppl , vol.369 , pp. 15-26
    • Johansson, B.1
  • 28
    • 0026469942 scopus 로고
    • The pharmacology and toxicology of disulfiram and its metabolites
    • Petersen EN. The pharmacology and toxicology of disulfiram and its metabolites. Acta Psychiatr Scand Suppl 1992; 369:7-13.
    • (1992) Acta Psychiatr Scand Suppl , vol.369 , pp. 7-13
    • Petersen, E.N.1
  • 29
    • 4644235752 scopus 로고    scopus 로고
    • Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease
    • Brar SS, Grigg C, Wilson KS, Holder WD Jr, Dreau D, Austin C, et al. Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease. Mol Cancer Ther 2004; 3:1049-1060.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1049-1060
    • Brar, S.S.1    Grigg, C.2    Wilson, K.S.3    Holder, W.D.4    Dreau, D.5    Austin, C.6
  • 30
    • 84885178939 scopus 로고    scopus 로고
    • Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells
    • Liu P, Kumar IS, Brown S, Kannappan V, Tawari PE, Tang JZ, et al. Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells. Br J Cancer 2013; 109:1876-1885.
    • (2013) Br J Cancer , vol.109 , pp. 1876-1885
    • Liu, P.1    Kumar, I.S.2    Brown, S.3    Kannappan, V.4    Tawari, P.E.5    Tang, J.Z.6
  • 31
    • 84867897977 scopus 로고    scopus 로고
    • Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells
    • Liu P, Brown S, Goktug T, Channathodiyil P, Kannappan V, Hugnot J-P, et al. Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells. Br J Cancer 2012; 107:1488-1497.
    • (2012) Br J Cancer , vol.107 , pp. 1488-1497
    • Liu, P.1    Brown, S.2    Goktug, T.3    Channathodiyil, P.4    Kannappan, V.5    Hugnot, J.-P.6
  • 32
    • 0029923258 scopus 로고    scopus 로고
    • Comparative study of the formation and repair of O6-methylguanine in humans and rodents treated with dacarbazine
    • Souliotis VL, Valavanis C, Boussiotis VA, Pangalis GA, Kyrtopoulos SA. Comparative study of the formation and repair of O6-methylguanine in humans and rodents treated with dacarbazine. Carcinogenesis 1996; 17:725-732.
    • (1996) Carcinogenesis , vol.17 , pp. 725-732
    • Souliotis, V.L.1    Valavanis, C.2    Boussiotis, V.A.3    Pangalis, G.A.4    Kyrtopoulos, S.A.5
  • 36
    • 0021722034 scopus 로고
    • Role of aldehyde dehydrogenase in cyclophosphamide-resistant L1210 leukemia
    • Hilton J. Role of aldehyde dehydrogenase in cyclophosphamide-resistant L1210 leukemia. Cancer Res 1984; 44:5156-5160.
    • (1984) Cancer Res , vol.44 , pp. 5156-5160
    • Hilton, J.1
  • 37
    • 84895819755 scopus 로고    scopus 로고
    • Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage
    • Paranjpe A, Zhang R, Ali-Osman F, Bobustuc GC, Srivenugopal KS. Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage. Carcinogenesis 2014; 35:692-702.
    • (2014) Carcinogenesis , vol.35 , pp. 692-702
    • Paranjpe, A.1    Zhang, R.2    Ali-Osman, F.3    Bobustuc, G.C.4    Srivenugopal, K.S.5
  • 38
    • 84869177666 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1A1 - A new mediator of resistance to temozolomide in glioblastoma
    • Schafer A, Teufel J, Ringel F, Bettstetter M, Hoepner I, Rasper M, et al. Aldehyde dehydrogenase 1A1 - a new mediator of resistance to temozolomide in glioblastoma. Neuro Oncol 2012; 14:1452-1464.
    • (2012) Neuro Oncol , vol.14 , pp. 1452-1464
    • Schafer, A.1    Teufel, J.2    Ringel, F.3    Bettstetter, M.4    Hoepner, I.5    Rasper, M.6
  • 40
    • 84875320058 scopus 로고    scopus 로고
    • Shortterm single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
    • Abubaker K, Latifi A, Luwor R, Nazaretian S, Zhu H, Quinn MA, et al. Shortterm single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden. Mol Cancer 2013; 12:24.
    • (2013) Mol Cancer , vol.12 , pp. 24
    • Abubaker, K.1    Latifi, A.2    Luwor, R.3    Nazaretian, S.4    Zhu, H.5    Quinn, M.A.6
  • 41
    • 79951825513 scopus 로고    scopus 로고
    • Ovarian cancer stem cell - Like side populations are enriched following chemotherapy and overexpress EZH2
    • Rizzo S, Hersey JM, Mellor P, Dai W, Santos-Silva A, Liber D, et al. Ovarian cancer stem cell - like side populations are enriched following chemotherapy and overexpress EZH2. Mol Cancer Ther 2011; 10:325-335.
    • (2011) Mol Cancer Ther , vol.10 , pp. 325-335
    • Rizzo, S.1    Hersey, J.M.2    Mellor, P.3    Dai, W.4    Santos-Silva, A.5    Liber, D.6
  • 42
    • 67449113764 scopus 로고    scopus 로고
    • Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers
    • Tanei T, Morimoto K, Shimazu K, Kim SJ, Tanji Y, Taguchi T, et al. Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin Cancer Res 2009; 15:4234-4241.
    • (2009) Clin Cancer Res , vol.15 , pp. 4234-4241
    • Tanei, T.1    Morimoto, K.2    Shimazu, K.3    Kim, S.J.4    Tanji, Y.5    Taguchi, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.