Microtrack migration: Insights into 3D cell motility. focus on “comparative mechanisms of cancer cell migration through 3d matrix and physiological microtracks”

American Journal of Physiology - Cell Physiology

Volumn 308, Issue 6, 2015, Pages C434-C435

  Rudzka, Dominika A ^a   Olson, Michael F ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; INTEGRIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN LIGHT CHAIN KINASE; COLLAGEN;

ACTIN POLYMERIZATION; ARTICLE; CANCER CELL; CELL ADHESION; CELL DENSITY; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CELL TRACKING; EXTRACELLULAR MATRIX; HUMAN; METASTASIS; MICROTUBULE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BREAST TUMOR; CELL MOTION; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; METABOLISM; TUMOR MICROENVIRONMENT;

ANIMALS; BREAST NEOPLASMS; CELL MOVEMENT; COLLAGEN; EXTRACELLULAR MATRIX; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; TUMOR MICROENVIRONMENT;

EID: 84924915868     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00016.2015     Document Type: Article

References (8)

1. Carey SP, Rahman A, Kraning-Rush CM, Romero B, Somasegar S, Torre OM, Williams RM, Reinhart-King CA. Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks. Am J Physiol Cell Physiol(December 10, 2014). doi:10.1152/ajpcell.00225.2014.
2. Carey SP, Starchenko A, McGregor AL, Reinhart-King CA. Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model. Clin Exp Metastasis30: 615–630, 2013.
3. Christofori G. New signals from the invasive front. Nature441: 444–450, 2006.
4. Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol9: 1392–1400, 2007.
5. Kraning-Rush CM, Carey SP, Lampi MC, Reinhart-King CA. Microfabricated collagen tracks facilitate single cell metastatic invasion in 3D. Integr Biol (Camb)5: 606–616, 2013.
6. Olson MF, Sahai E. The actin cytoskeleton in cancer cell motility. Clin Exp Metastasis26: 273–287, 2009.
7. Scott RW, Hooper S, Crighton D, Li A, König I, Munro J, Trivier E, Wickman G, Morin P, Croft DR, Dawson J, Machesky L, Anderson KI, Sahai EA, Olson MF. LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol191: 169–185, 2010.
8. Tozluoglu M, Tournier AL, Jenkins RP, Hooper S, Bates PA, Sahai E. Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions. Nat Cell Biol15: 751–762, 2013.