Hypothalamus metabolomic profiling to elucidate the tissue-targeted biochemical basis of febrile response in yeast-induced pyrexia rats

Chemico-Biological Interactions

Volumn 231, Issue , 2015, Pages 61-70

  Liu, Haiyu ^a   Zhang, Li ^a   Zhao, Baosheng ^a   Zhang, Zhixin ^a   Qin, Lingling ^a   Zhang, Qingqing ^a   Wang, Qing ^a   Lu, Zhiwei ^a   Gao, Xiaoyan ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Fever; HPLC LTQ Orbitrap MS; Hypothalamus; Metabolomics; Thermoregulatory mechanisms

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; CARBOHYDRATE; NUCLEIC ACID; PHOSPHOLIPID; VITAMIN;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; ENERGY METABOLISM; FEVER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHALAMUS; INFORMATION PROCESSING; LIPID METABOLISM; MALE; MASS SPECTROMETRY; METABOLOMICS; NONHUMAN; PARTIAL LEAST SQUARES REGRESSION; PATHOGENESIS; PRINCIPAL COMPONENT ANALYSIS; PURINE METABOLISM; RAT; THERMOREGULATION; YEAST; ANIMAL; CANDIDIASIS; COMPLICATION; ISOLATION AND PURIFICATION; METABOLISM; METABOLOME; MULTIVARIATE ANALYSIS; PATHOPHYSIOLOGY; REGRESSION ANALYSIS; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BODY TEMPERATURE REGULATION; CANDIDIASIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISCRIMINANT ANALYSIS; FEVER; HYPOTHALAMUS; LEAST-SQUARES ANALYSIS; LIPID METABOLISM; MALE; MASS SPECTROMETRY; METABOLOME; MULTIVARIATE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; YEASTS;

EID: 84924853017     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.02.018     Document Type: Article

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