Polymorphism in Sulfadimidine/4-Aminosalicylic Acid Cocrystals: Solid-State Characterization and Physicochemical Properties

Journal of Pharmaceutical Sciences

Volumn 104, Issue 4, 2015, Pages 1385-1398

  Grossjohann, Christine ^a   Serrano, Dolores R ^a   Paluch, Krzysztof J ^a   O'Connell, Peter ^a   Vella Zarb, Liana ^b   Manesiotis, Panagiotis ^c   McCabe, Thomas ^a   Tajber, Lidia ^a   Corrigan, Owen I ^a   Healy, Anne Marie ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF MALTA   (Malta)

^c South East Technological University   (Ireland)

Author keywords

4 aminosalicylic acid; cocrystals; dissolution; milling; polymorphism; solid state; solubility; spray drying; sulfadimidine

Indexed keywords

AMINOSALICYLIC ACID; SULFADIMIDINE; ACETONE; ALCOHOL; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; DRUG COMBINATION; SOLVENT;

ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; CRYSTAL; CRYSTAL STRUCTURE; DISSOLUTION; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ELEMENTAL ANALYSIS; HYDROGEN BOND; INFRARED SPECTROSCOPY; MOLECULAR INTERACTION; PH; PHYSICAL CHEMISTRY; SOLID; SOLID STATE; SPRAY DRYING; THERMAL ANALYSIS; X RAY POWDER DIFFRACTION; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CRYSTALLIZATION; DRUG COMBINATION; DRUG STABILITY; KINETICS; MEDICINAL CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHARMACEUTICS; POWDER DIFFRACTION; PROCEDURES; SOLUBILITY; TEMPERATURE; X RAY CRYSTALLOGRAPHY;

ACETONE; AMINOSALICYLIC ACID; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DRUG COMBINATIONS; DRUG STABILITY; ETHANOL; HYDROGEN-ION CONCENTRATION; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; POWDER DIFFRACTION; SOLUBILITY; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SULFAMETHAZINE; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 84924804830     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24345     Document Type: Article

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