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Volumn 10, Issue 1, 2012, Pages

Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE ® bioreactor

Author keywords

Adoptive immunotherapy; Human; T cell receptors; T cells; Tumor immunity

Indexed keywords

RETROVIRUS VECTOR; GAMMA INTERFERON; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84859179612     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-69     Document Type: Article
Times cited : (80)

References (34)
  • 1
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • 10.1200/JCO.2009.23.4799, 2793035, 19917835
    • Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009, 27:6199-6206. 10.1200/JCO.2009.23.4799, 2793035, 19917835.
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.J.3    Thompson, J.F.4    Atkins, M.B.5    Byrd, D.R.6
  • 2
    • 0033989205 scopus 로고    scopus 로고
    • Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
    • Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S, et al. Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol 2000, 18:158-166.
    • (2000) J Clin Oncol , vol.18 , pp. 158-166
    • Middleton, M.R.1    Grob, J.J.2    Aaronson, N.3    Fierlbeck, G.4    Tilgen, W.5    Seiter, S.6
  • 3
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
    • Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 1999, 17:2105-2116.
    • (1999) J Clin Oncol , vol.17 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3    Fisher, R.I.4    Weiss, G.5    Margolin, K.6
  • 4
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • 10.1056/NEJMoa1003466, 20525992
    • Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010, 363:711-723. 10.1056/NEJMoa1003466, 20525992.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3    Weber, R.W.4    Sosman, J.A.5    Haanen, J.B.6
  • 5
    • 0033848628 scopus 로고    scopus 로고
    • High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update
    • Atkins MB, Kunkel L, Sznol M, Rosenberg SA. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am 2000, 6(Suppl 1):S11-S14.
    • (2000) Cancer J Sci Am , vol.6 , Issue.SUPPL. 1
    • Atkins, M.B.1    Kunkel, L.2    Sznol, M.3    Rosenberg, S.A.4
  • 6
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • 10.1056/NEJMoa1002011, 20818844
    • Flaherty KT, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010, 363:809-819. 10.1056/NEJMoa1002011, 20818844.
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3    Ribas, A.4    McArthur, G.A.5    Sosman, J.A.6
  • 7
    • 41149097574 scopus 로고    scopus 로고
    • Adoptive cell transfer: a clinical path to effective cancer immunotherapy
    • 10.1038/nrc2355, 2553205, 18354418
    • Rosenberg SA, Restifo NP, Yang JC, Morgan RA, Dudley ME. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer 2008, 8:299-308. 10.1038/nrc2355, 2553205, 18354418.
    • (2008) Nat Rev Cancer , vol.8 , pp. 299-308
    • Rosenberg, S.A.1    Restifo, N.P.2    Yang, J.C.3    Morgan, R.A.4    Dudley, M.E.5
  • 8
    • 0037829421 scopus 로고    scopus 로고
    • Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
    • 10.1097/00002371-200307000-00005, 2305721, 12843795
    • Dudley ME, Wunderlich JR, Shelton TE, Even J, Rosenberg SA. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother 2003, 26:332-342. 10.1097/00002371-200307000-00005, 2305721, 12843795.
    • (2003) J Immunother , vol.26 , pp. 332-342
    • Dudley, M.E.1    Wunderlich, J.R.2    Shelton, T.E.3    Even, J.4    Rosenberg, S.A.5
  • 9
    • 78650316191 scopus 로고    scopus 로고
    • CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma
    • 10.1158/1078-0432.CCR-10-1297, 2978753, 20668005
    • Dudley ME, Gross CA, Langhan MM, Garcia MR, Sherry RM, Yang JC, et al. CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma. Clin Cancer Res 2010, 16:6122-6131. 10.1158/1078-0432.CCR-10-1297, 2978753, 20668005.
    • (2010) Clin Cancer Res , vol.16 , pp. 6122-6131
    • Dudley, M.E.1    Gross, C.A.2    Langhan, M.M.3    Garcia, M.R.4    Sherry, R.M.5    Yang, J.C.6
  • 10
    • 79960299888 scopus 로고    scopus 로고
    • Durable Complete Responses in Heavily Pretreted Patients with Metastatic Melanoma Using T Cell Transfer Immunotherapy
    • Rosenberg SA, Yang JC, Sherry RM, Kammula US, Hughes MS, Phan GQ, et al. Durable Complete Responses in Heavily Pretreted Patients with Metastatic Melanoma Using T Cell Transfer Immunotherapy. Clin Cancer Res 2011, 13:4550-7.
    • (2011) Clin Cancer Res , vol.13 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3    Kammula, U.S.4    Hughes, M.S.5    Phan, G.Q.6
  • 11
    • 77957981209 scopus 로고    scopus 로고
    • Adoptive cell therapy: genetic modification to redirect effector cell specificity
    • 10.1097/PPO.0b013e3181eb3879, 20693844
    • Morgan RA, Dudley ME, Rosenberg SA. Adoptive cell therapy: genetic modification to redirect effector cell specificity. Cancer J 2010, 16:336-341. 10.1097/PPO.0b013e3181eb3879, 20693844.
    • (2010) Cancer J , vol.16 , pp. 336-341
    • Morgan, R.A.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 12
    • 79952304769 scopus 로고    scopus 로고
    • Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
    • 10.1200/JCO.2010.32.2537, 3068063, 21282551
    • Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol 2011, 29:917-924. 10.1200/JCO.2010.32.2537, 3068063, 21282551.
    • (2011) J Clin Oncol , vol.29 , pp. 917-924
    • Robbins, P.F.1    Morgan, R.A.2    Feldman, S.A.3    Yang, J.C.4    Sherry, R.M.5    Dudley, M.E.6
  • 13
    • 78549278144 scopus 로고    scopus 로고
    • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
    • 10.1182/blood-2010-04-281931, 2993617, 20668228
    • Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler-Stevenson M, Feldman SA, et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood 2010, 116:4099-4102. 10.1182/blood-2010-04-281931, 2993617, 20668228.
    • (2010) Blood , vol.116 , pp. 4099-4102
    • Kochenderfer, J.N.1    Wilson, W.H.2    Janik, J.E.3    Dudley, M.E.4    Stetler-Stevenson, M.5    Feldman, S.A.6
  • 14
    • 79952187823 scopus 로고    scopus 로고
    • T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    • 10.1038/mt.2010.272, 3048186, 21157437
    • Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2011, 19:620-626. 10.1038/mt.2010.272, 3048186, 21157437.
    • (2011) Mol Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1    Yang, J.C.2    Langan, R.C.3    Dudley, M.E.4    Nathan, D.A.5    Feldman, S.A.6
  • 15
    • 77953044135 scopus 로고    scopus 로고
    • Enrichment of CD8+ cells from melanoma tumor-infiltrating lymphocyte cultures reveals tumor reactivity for use in adoptive cell therapy
    • 10.1097/CJI.0b013e3181d367bd, 20463593
    • Prieto PA, Durflinger KH, Wunderlich JR, Rosenberg SA, Dudley ME. Enrichment of CD8+ cells from melanoma tumor-infiltrating lymphocyte cultures reveals tumor reactivity for use in adoptive cell therapy. J Immunother 2010, 33:547-556. 10.1097/CJI.0b013e3181d367bd, 20463593.
    • (2010) J Immunother , vol.33 , pp. 547-556
    • Prieto, P.A.1    Durflinger, K.H.2    Wunderlich, J.R.3    Rosenberg, S.A.4    Dudley, M.E.5
  • 16
    • 84865283648 scopus 로고    scopus 로고
    • Manufacturing of large numbers of patient-specific T cells for adoptive immunotherapy: an approach to improving product safety, composition, and production capacity
    • Tran CA. Manufacturing of large numbers of patient-specific T cells for adoptive immunotherapy: an approach to improving product safety, composition, and production capacity. 2007,
    • (2007)
    • Tran, C.A.1
  • 17
    • 84865302663 scopus 로고    scopus 로고
    • Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy
    • Tran KQ. Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy. 2008,
    • (2008)
    • Tran, K.Q.1
  • 18
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
    • 10.1182/blood-2009-03-211714, 2929689, 19451549
    • Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009, 114:535-546. 10.1182/blood-2009-03-211714, 2929689, 19451549.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3    Cassard, L.4    Yang, J.C.5    Hughes, M.S.6
  • 19
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • 10.1126/science.1129003, 2267026, 16946036
    • Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006, 314:126-129. 10.1126/science.1129003, 2267026, 16946036.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3    Hughes, M.S.4    Yang, J.C.5    Sherry, R.M.6
  • 20
    • 0034607636 scopus 로고    scopus 로고
    • Culture of human T cells in stirred bioreactors for cellular immunotherapy applications: shear, proliferation, and the IL-2 receptor
    • 10.1002/(SICI)1097-0290(20000505)68:3<328::AID-BIT11>3.0.CO;2-V, 10745201
    • Carswell KS, Papoutsakis ET. Culture of human T cells in stirred bioreactors for cellular immunotherapy applications: shear, proliferation, and the IL-2 receptor. Biotechnol Bioeng 2000, 68:328-338. 10.1002/(SICI)1097-0290(20000505)68:3<328::AID-BIT11>3.0.CO;2-V, 10745201.
    • (2000) Biotechnol Bioeng , vol.68 , pp. 328-338
    • Carswell, K.S.1    Papoutsakis, E.T.2
  • 21
    • 11144257840 scopus 로고    scopus 로고
    • GMP production and testing of Xcellerated T Cells for the treatment of patients with CLL
    • 10.1080/14653240410005348, 15764021
    • Hami LS, Green C, Leshinsky N, Markham E, Miller K, Craig S. GMP production and testing of Xcellerated T Cells for the treatment of patients with CLL. Cytotherapy 2004, 6:554-562. 10.1080/14653240410005348, 15764021.
    • (2004) Cytotherapy , vol.6 , pp. 554-562
    • Hami, L.S.1    Green, C.2    Leshinsky, N.3    Markham, E.4    Miller, K.5    Craig, S.6
  • 22
    • 42149096101 scopus 로고    scopus 로고
    • T lymphocyte engineering ex vivo for cancer and infectious disease
    • 10.1517/14712598.8.4.475, 18352851
    • Levine BL. T lymphocyte engineering ex vivo for cancer and infectious disease. Expert Opin Biol Ther 2008, 8:475-489. 10.1517/14712598.8.4.475, 18352851.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 475-489
    • Levine, B.L.1
  • 23
    • 65749108349 scopus 로고    scopus 로고
    • Single-pass, closed-system rapid expansion of lymphocyte cultures for adoptive cell therapy
    • 10.1016/j.jim.2009.04.009, 2700005, 19389403
    • Klapper JA, Thomasian AA, Smith DM, Gorgas GC, Wunderlich JR, Smith FO, et al. Single-pass, closed-system rapid expansion of lymphocyte cultures for adoptive cell therapy. J Immunol Methods 2009, 345:90-99. 10.1016/j.jim.2009.04.009, 2700005, 19389403.
    • (2009) J Immunol Methods , vol.345 , pp. 90-99
    • Klapper, J.A.1    Thomasian, A.A.2    Smith, D.M.3    Gorgas, G.C.4    Wunderlich, J.R.5    Smith, F.O.6
  • 24
    • 78650849200 scopus 로고    scopus 로고
    • Large-scale bioreactor expansion of tumor-infiltrating lymphocytes
    • 10.1016/j.jim.2010.11.007, 21111743
    • Sadeghi A, Pauler L, Anneren C, Friberg A, Brandhorst D, Korsgren O, et al. Large-scale bioreactor expansion of tumor-infiltrating lymphocytes. J Immunol Methods 2011, 364:94-100. 10.1016/j.jim.2010.11.007, 21111743.
    • (2011) J Immunol Methods , vol.364 , pp. 94-100
    • Sadeghi, A.1    Pauler, L.2    Anneren, C.3    Friberg, A.4    Brandhorst, D.5    Korsgren, O.6
  • 25
    • 63649112916 scopus 로고    scopus 로고
    • Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy
    • 10.1097/CJI.0b013e318194a6e8, 2683970, 19238016
    • Hollyman D, Stefanski J, Przybylowski M, Bartido S, Borquez-Ojeda O, Taylor C, et al. Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy. J Immunother 2009, 32:169-180. 10.1097/CJI.0b013e318194a6e8, 2683970, 19238016.
    • (2009) J Immunother , vol.32 , pp. 169-180
    • Hollyman, D.1    Stefanski, J.2    Przybylowski, M.3    Bartido, S.4    Borquez-Ojeda, O.5    Taylor, C.6
  • 26
    • 62849108442 scopus 로고    scopus 로고
    • Application of Disposable Bag-Bioreactors in Tissue Engineering and for the Production of Therapeutic Agents
    • Eibl R, Eibl D. Application of Disposable Bag-Bioreactors in Tissue Engineering and for the Production of Therapeutic Agents. Adv Biochem Eng Biotechnol 2009, 112:183-207.
    • (2009) Adv Biochem Eng Biotechnol , vol.112 , pp. 183-207
    • Eibl, R.1    Eibl, D.2
  • 27
    • 77951714425 scopus 로고    scopus 로고
    • Clinical Responses in a Phase II Study Using Adoptive Transfer of Short-term Cultured Tumor Infiltration Lymphocytes in Metastatic Melanoma Patients
    • 10.1158/1078-0432.CCR-10-0041, 20406835
    • Besser MJ, Shapira-Frommer R, Treves AJ, Zippel D, Itzhaki O, Hershkovitz L, et al. Clinical Responses in a Phase II Study Using Adoptive Transfer of Short-term Cultured Tumor Infiltration Lymphocytes in Metastatic Melanoma Patients. Clin Cancer Res 2010, 16:2646-2655. 10.1158/1078-0432.CCR-10-0041, 20406835.
    • (2010) Clin Cancer Res , vol.16 , pp. 2646-2655
    • Besser, M.J.1    Shapira-Frommer, R.2    Treves, A.J.3    Zippel, D.4    Itzhaki, O.5    Hershkovitz, L.6
  • 28
    • 20444499355 scopus 로고    scopus 로고
    • Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
    • 10.1172/JCI24480, 1137001, 15931392
    • Gattinoni L, Klebanoff CA, Palmer DC, Wrzesinski C, Kerstann K, Yu Z, et al. Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells. J Clin Invest 2005, 115:1616-1626. 10.1172/JCI24480, 1137001, 15931392.
    • (2005) J Clin Invest , vol.115 , pp. 1616-1626
    • Gattinoni, L.1    Klebanoff, C.A.2    Palmer, D.C.3    Wrzesinski, C.4    Kerstann, K.5    Yu, Z.6
  • 29
    • 22144437688 scopus 로고    scopus 로고
    • Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
    • 10.1073/pnas.0503726102, 1172264, 15980149
    • Klebanoff CA, Gattinoni L, Torabi-Parizi P, Kerstann K, Cardones AR, Finkelstein SE, et al. Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci USA 2005, 102:9571-9576. 10.1073/pnas.0503726102, 1172264, 15980149.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9571-9576
    • Klebanoff, C.A.1    Gattinoni, L.2    Torabi-Parizi, P.3    Kerstann, K.4    Cardones, A.R.5    Finkelstein, S.E.6
  • 30
    • 25844484607 scopus 로고    scopus 로고
    • Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
    • 10.1084/jem.20050732, 1397916,1397916, 16203864
    • Gattinoni L, Finkelstein SE, Klebanoff CA, Antony PA, Palmer DC, Spiess PJ, et al. Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells. J Exp Med 2005, 202:907-912. 10.1084/jem.20050732, 1397916,1397916, 16203864.
    • (2005) J Exp Med , vol.202 , pp. 907-912
    • Gattinoni, L.1    Finkelstein, S.E.2    Klebanoff, C.A.3    Antony, P.A.4    Palmer, D.C.5    Spiess, P.J.6
  • 31
    • 0025486770 scopus 로고
    • Sparged animal cell bioreactors: mechanism of cell damage and Pluronic F-68 protection
    • 10.1021/bp00005a012, 1366875
    • Murhammer DW, Goochee CF. Sparged animal cell bioreactors: mechanism of cell damage and Pluronic F-68 protection. Biotechnol Prog 1990, 6:391-397. 10.1021/bp00005a012, 1366875.
    • (1990) Biotechnol Prog , vol.6 , pp. 391-397
    • Murhammer, D.W.1    Goochee, C.F.2
  • 32
    • 84865302796 scopus 로고    scopus 로고
    • Cell therapy with human T regulatory type 1 cells in allogeneic transplantations
    • Bacchetta R, Gregori S, Barbarella L, Roncarolo MG. Cell therapy with human T regulatory type 1 cells in allogeneic transplantations. Immunotherapy 2011, 3:27.
    • (2011) Immunotherapy , vol.3 , pp. 27
    • Bacchetta, R.1    Gregori, S.2    Barbarella, L.3    Roncarolo, M.G.4
  • 33
    • 28744452210 scopus 로고    scopus 로고
    • Von HM: Antigen-specific induction of regulatory T cells for type 1 diabetes therapy
    • 10.1080/08830180500371116, 16318986
    • Filippi C, Bresson D, von Herrath M. von HM: Antigen-specific induction of regulatory T cells for type 1 diabetes therapy. Int Rev Immunol 2005, 24:341-360. 10.1080/08830180500371116, 16318986.
    • (2005) Int Rev Immunol , vol.24 , pp. 341-360
    • Filippi, C.1    Bresson, D.2    von Herrath, M.3
  • 34
    • 76949100884 scopus 로고    scopus 로고
    • Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex)
    • 10.1097/CJI.0b013e3181c0c3cb, 2946348, 20445351
    • Vera JF, Brenner LJ, Gerdemann U, Ngo MC, Sili U, Liu H, et al. Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex). J Immunother 2010, 33:305-315. 10.1097/CJI.0b013e3181c0c3cb, 2946348, 20445351.
    • (2010) J Immunother , vol.33 , pp. 305-315
    • Vera, J.F.1    Brenner, L.J.2    Gerdemann, U.3    Ngo, M.C.4    Sili, U.5    Liu, H.6


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