Ellagic acid derivatives from Terminalia chebula Retz. increase the susceptibility of Pseudomonas aeruginosa to stress by inhibiting polyphosphate kinase

Journal of Applied Microbiology

Volumn 118, Issue 4, 2015, Pages 817-825

  Sarabhai, S ^a   Harjai, K ^a   Sharma, P ^a   Capalash, N ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Ellagic acid derivatives; Motilities; Persister cells; ppk; Ps. aeruginosa; RpoS; Stress; Terminalia chebula

Indexed keywords

BACTERIA; ELLAGIC ACID; ENZYMES; GENE EXPRESSION;

ACID DERIVATIVE; ELLAGIC ACID DERIVATIVE; MOTILITY; PERSISTER CELLS; POLYPHOSPHATES; PPK; PS. AERUGINOSA; PSEUDOMONAS AERUGINOSA; RPO; TERMINALIA CHEBULA;

ANTIBIOTICS;

ELLAGIC ACID; ELLAGIC ACID DERIVATIVE; HYDROGEN PEROXIDE; PIPERACILLIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; PHOSPHOTRANSFERASE; PLANT EXTRACT; POLYPHOSPHATE; POLYPHOSPHATE KINASE;

ANTIBIOTIC RESISTANCE; ANTIOXIDANT; BACTERIUM; DICOTYLEDON; ENZYME ACTIVITY; GENE EXPRESSION; INHIBITION; MOTILITY; OXIDATION; PHOSPHATE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BIOFILM; CYTOSOL; DESICCATION; DOWN REGULATION; DRUG EFFECT; GENE EXPRESSION; GROWTH INHIBITION; IN VITRO STUDY; NONHUMAN; POLYPHOSPHATE KINASE 1 GENE; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; STRESS; SWIMMING; TERMINALIA CHEBULA; TWITCHING MOTILITY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; TERMINALIA;

PSEUDOMONAS AERUGINOSA; TERMINALIA CHEBULA;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; ELLAGIC ACID; HUMANS; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); PLANT EXTRACTS; POLYPHOSPHATES; PSEUDOMONAS AERUGINOSA; TERMINALIA;

EID: 84924787199     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.12733     Document Type: Article

References (29)

1. Babic, F., Venturi, V. and Vlahoviek, G.M. (2010) Tobramycin at subinhibitory concentration inhibits the RhlI/R quorum sensing system in a Pseudomonas aeruginosa environmental isolate. BMC Infect Dis 10, 148-160.
2. Bag, A., Bhattacharyya, S.K. and Chattopadhyay, R.R. (2013) The development of Terminalia chebula Retz. (Combretaceae) in clinical research. Asian Pac J Trop Biomed 3, 244-252.
3. Brown, M.R.W. and Kornberg, A. (2008) The long and short of it - polyphosphate, PPK and bacterial survival. Trends Biochem Sci 33, 284-290.
4. Caiazza, N.C., Shanks, R.M.Q. and O'Toole, G.A. (2005) Rhamnolipids modulate swarming motility patterns of Pseudomonas aeruginosa. J Bacteriol 187, 7351-7361.
5. Camci, I.Y., Doruk, T., Avican, U. and Tunca Gedik, S.T. (2012) Deletion of polyphosphate kinase gene (ppk) has a stimulatory effect on actinorhodin production by Streptomyces coelicolor. Turk J Biol 36, 373-380.
6. Chavez, F.P., Lagos, C.F., Parada, M.R., Guiliani, N. and Jerez, C.A. (2011) Polyphosphate synthesis as a target for novel antibiotics. Curr Enzym Inhib 7, 163-168.
7. Deredjian, A., Colinon, C., Brothier, E., Favre-Bonte, S., Cournoyer, B. and Nazaret, S. (2011) Antibiotic and metal resistance among hospital and outdoor strains of Pseudomonas aeruginosa. Res Microbiol 162, 689-700.
8. Fraley, C.D., Rashid, M.H., Lee, S.S.K., Gottschalk, R., Harrison, J., Wood, P.J., Brown, M.R.W. and Kornberg, A. (2007) A polyphosphate kinase 1 (ppk1) mutant of Pseudomonas aeruginosa exhibits multiple ultrastructural and functional defects. Proc Natl Acad Sci USA 104, 3526-3531.
9. Hassett, D.J., Ma, J.F., Elkins, J.G., McDermott, T.R., Ochsner, U.A., West, S.E.H., Huang, C.T., Fredericks, J. et al. (1999) Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide. Mol Microbiol 34, 1082-1093.
10. Kornberg, A. (1995) Inorganic polyphosphate: toward making a forgotten polymer unforgettable. J Bacteriol 177, 491-496.
11. Kus, J.V., Tullis, E., Cvitkovitch, D.G. and Burrows, L.L. (2004) Significant differences in type IV pilin allele distribution among Pseudomonas aeruginosa isolates from cystic fibrosis (CF) versus non-CF patients. Microbiology 150, 1315-1326.
12. Levin, B.R. and Rozen, D.E. (2006) Non inherited antibiotic resistance. Natl Rev Microbiol 4, 556-562.
13. Manoil, C., Jacobs, M.A., Alwood, A., Thaipisuttikul, I., Spencer, D., Haugen, E., Ernst, S., Will, O. et al. (2003) Comprehensive transposon mutant library of Pseudomonas aeruginosa. Proc Natl Acad Sci USA 100, 14339-14344.
14. Moker, N., Dean, C.R. and Tao, J. (2010) Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to Quorum-Sensing signaling molecules. J Bacteriol 192, 1946-1955.
15. Mullan, A., Quinn, J.P. and McGrath, J.W. (2002) A nonradioactive method for the assay of polyphosphate kinase activity and its application in the study of polyphosphate metabolism in Burkholderia cepacia. Anal Biochem 308, 294-299.
16. Murakami, K., Ono, T., Viducic, D., Kayama, S., Mori, M., Hirota, K., Nemoto, K. and Iyake, Y. (2005) Role of rpoS gene of Pseudomonas aeruginosa in antibiotic tolerance. FEMS Microbiol Lett 242, 161-167.
17. O'Toole, G.A. and Kolter, R. (1998) Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development. Mol Microbiol 30, 295-304.
18. Pendleton, J.N., Gorman, S.P. and Gilmore, B.F. (2013) Clinical relevance of the ESKAPE pathogens. Expert Rev Anti Infect Ther 11, 297-308.
19. Pfundstein, B., Desouky, S.K.E., Hull, W.E., Haunber, R., Erben, G. and Owen, R.W. (2010) Polyphenolic compounds in the fruit of Egyptian medicinal plants (Terminalia bellerica, Terminalia chebula and Terminalia horrida): characterization, quantitation and determination of antioxidant capacities. Phytochemistry 71, 1132-1148.
20. Rashid, M.H., Rumbaugh, K., Passador, L., Davies, D.G., Hamood, A.N., Iglewski, B.H. and Kornberg, A. (2000) Polyphosphate kinase is essential for biofilm development, quorum sensing, and virulence of Pseudomonas aeruginosa. Proc Natl Acad Sci USA 97, 9636-9641.
21. Sarabhai, S., Sharma, P. and Capalash, N. (2013) Ellagic acid derivatives from Terminalia chebula Retz. downregulate the expression of quorum sensing genes to attenuate Pseudomonas aeruginosa PAO1 virulence. PLoS One 8, e53441.
22. Shiba, T., Tsutsumi, K., Yano, H., Ihara, Y., Kameda, M.R.W., Tanaka, K., Takahashi, H., Masanobu, M. et al. (1997) Inorganic polyphosphate and the induction of rpoS expression. Proc Natl Acad Sci USA 94, 11210-11215.
23. Shum, K.T., Lui, E.L.K., Wong, S.C.K., Yeung, P., Sam, L., Wang, Y., Watt, R.M. and Tanner, J.A. (2011) Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase 2. Biochemistry 50, 3261-3271.
24. Tunpiboonsak, S., Mongkolrob, R., Kitudomsub, K., Thanwatanaying, P., Kiettipirodom Rungrawee, W., Tungboontina, Y. and Tungpradabkul, S. (2010) Role of a Burkholderia pseudomallei polyphosphate kinase in an oxidative stress response, motilities, and biofilm formation. J Microbiol 48, 63-70.
25. Tzeng, C.M. and Kornberg, A. (1998) Polyphosphate kinase is highly conserved in many bacterial pathogens. Mol Microbiol 29, 381-382.
26. Viducic, D., Ono, T., Murakami, K., Susilowati, H., Kayama, S., Horota, S.K. and Miyake, Y. (2006) Functional analysis of SpoT, RelA, Dsk A genes on quinolone tolerance in Pseudomonas aeruginosa under non growing conditions. Microbiol Immunol 50, 349-357.
27. Zhang, H., Ishige, K. and Kornberg, A. (2002) Polyphosphate kinase (PPK2) widely conserved in bacteria. Proc. Nat. Acad. Sci. USA 99, 16678-16683.
28. Zhang, H., Gomez-Garcia, M.R., Brown, M.R.W. and Kornberg, A. (2005) Inorganic polyphosphate in Dictyostelium discoideum: influence on development, sporulation, and predation. Proc Natl Acad Sci USA 102, 2731-2735.
29. Zhu, Y., Huang, W., Lee, S.S.K. and Xu, W. (2005) Crystal structure of a polyphosphate kinase and its implications for polyphosphate synthesis. EMBO Rep 6, 681-687.