Polyphosphate synthesis as a target for novel antibiotics

Current Enzyme Inhibition

Volumn 7, Issue 3, 2011, Pages 163-168

  Chávez, Francisco P ^a,b   Lagos, Carlos F ^c   Reyes Parada, Miguel ^b,d,e   Guiliani, Nicolás ^a   Jerez, Carlos A ^a,b  

^a UNIVERSITY OF CHILE   (Chile)

^b Iniciativa Cientifica Milenio Santiago   (Chile)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^d UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^e UNIVERSIDAD AUTÓNOMA DE CHILE   (Chile)

Author keywords

Antibiotics; Chemical biology; In silico drug design; Pathogenic bacteria; Polyphosphate; Polyphosphate kinase 1; Ppk1 inhibitors; Virulence

Indexed keywords

ADENOSINE 5 PHOSPHATE DERIVATIVE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANTIBIOTIC AGENT; BACTERIAL ENZYME; GUANIDINE; POLYPHOSPHATE; POLYPHOSPHATE KINASE 1; POLYPHOSPHATE KINASE 1 INHIBITOR; POLYPHOSPHATE KINASE 2; PYROPHOSPHATE; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; BACTERIAL GENE; BACTERIAL VIRULENCE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; ESCHERICHIA COLI; GENE DELETION; HELICOBACTER PYLORI; IC 50; MYCOBACTERIUM TUBERCULOSIS; NEISSERIA MENINGITIDIS; NONHUMAN; PROTEIN STRUCTURE; REVIEW; SHIGELLA FLEXNERI; VIBRIO CHOLERAE;

BACTERIA (MICROORGANISMS); EUKARYOTA; PROKARYOTA;

EID: 84855292836     PISSN: 15734080     EISSN: 18756662     Source Type: Journal    
DOI: 10.2174/157340811798807605     Document Type: Review

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