Discovery of novel multiacting topoisomerase I/II and histone deacetylase inhibitors

ACS Medicinal Chemistry Letters

Volumn 6, Issue 3, 2015, Pages 239-243

  He, Shipeng ^a   Dong, Guoqiang ^b   Wang, Zhibin ^b   Chen, Wei ^b   Huang, Yahui ^b   Li, Zhengang ^b   Jiang, Yan ^b   Liu, Na ^b   Yao, Jianzhong ^b   Miao, Zhenyuan ^b   Zhang, Wannian ^b   Sheng, Chunquan ^a,b  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

antiproliferative activity; Evodiamine derivatives; histone deacetylase; topoisomerase I; topoisomerase II

Indexed keywords

3 AMINO 10 HYDROXYLEVODIAMINE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE INHIBITOR; EVODIAMINE; HISTONE DEACETYLASE INHIBITOR; UNCLASSIFIED DRUG; VORINOSTAT;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYBRID; MOLECULE; PRIORITY JOURNAL;

EID: 84924738690     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml500327q     Document Type: Article

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