Response monitoring of infant acute myeloid leukemia treatment by quantification of the tumor specific MLLFNBP1 fusion gene

Leukemia and Lymphoma

Volumn 56, Issue 3, 2015, Pages 793-796

  Krumbholz, Manuela ^a   Jung, Ronny ^a   Bradtke, Jutta ^b   Reinhardt, Dirk ^c   Stachel, Daniel ^a   Metzler, Markus ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY HOSPITAL GIESSEN   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARRIER PROTEIN; CYTARABINE; FNBP1 PROTEIN, HUMAN; MITOXANTRONE; MIXED LINEAGE LEUKEMIA PROTEIN; ONCOPROTEIN;

ACUTE DISEASE; CASE REPORT; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; HUMAN; INFANT; KARYOTYPE; LEUKEMIA, MYELOID; REMISSION; TREATMENT OUTCOME;

ACUTE DISEASE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARRIER PROTEINS; CYTARABINE; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; KARYOTYPE; LEUKEMIA, MYELOID; MITOXANTRONE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; ONCOGENE PROTEINS, FUSION; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 84924731329     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2014.928933     Document Type: Letter

References (15)

1. Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 2007;7:823-833.
2. Meyer C, Hofmann J, Burmeister T, et al. The MLL recombinome of acute leukemias in 2013. Leukemia 2013;27:2165-2176.
3. Balgobind BV, Raimondi SC, Harbott J, et al. Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study. Blood 2009;114:2489-2496.
4. Creutzig U, van den Heuvel-Eibrink MM, Gibson B, et al. Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel. Blood 2012;120:3187-3205.
5. von Neuhoff C, Reinhardt D, Sander A, et al. Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98. J Clin Oncol 2010;28:2682-2689.
6. Balgobind BV, Zwaan CM, Pieters R, et al. The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia. Leukemia 2011;25:1239-1248.
7. Creutzig U, Zimmermann M, Bourquin JP, et al. Favorable outcome in infants with AML after intensive first- and second-line treatment: an AML-BFM study group report. Leukemia 2012;26:654-661.
8. Jung R, Jacobs U, Krumbholz M, et al. Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment. Leukemia 2010;24:903-907.
9. Fuchs U, Rehkamp G, Haas OA, et al. The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. Proc Natl Acad Sci USA 2001;98:8756-8761.
10. Fuchs U, Rehkamp GF, Slany R, et al. The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance. FEBS Lett 2003;554:10-16.
11. Shtalrid M, Lotem J, Sachs L, et al. Review of clinical and haematological response to low-dose cytosine arabinoside in acute myeloid leukaemia. Eur J Haematol 1987;38:3-11.
12. Jurlander J, Caligiuri MA, Ruutu T, et al. Persistence of the AML1/ETO fusion transcript in patients treated with allogeneic bone marrow transplantation for t(8;21) leukemia. Blood 1996;88:2183-2191.
13. Guerrasio A, Pilatrino C, De Micheli D, et al. Assessment of minimal residual disease (MRD) in CBFbeta/MYH11-positive acute myeloid leukemias by qualitative and quantitative RT-PCR amplification of fusion transcripts. Leukemia 2002;16:1176-1181.
14. Kowarz E, Dingermann T, Marschalek R. Do non-genomically encoded fusion transcripts cause recurrent chromosomal translocations? Cancers (Basel) 2012;4:1036-1049.
15. Varella-Garcia M, Hogan CJ, Odom LF, et al. Minimal residual disease (MRD) in remission t(8;21) AML and in vivo differentiation detected by FISH and CD34 + cell sorting. Leukemia 2001;15:1408-1414.