Excess of heme induces tissue factor-dependent activation of coagulation in mice

Haematologica

Volumn 100, Issue 3, 2015, Pages 308-313

  Sparkenbaugh, Erica M ^a   Chantrathammachart, Pichika ^a,b   Wang, Shaobin ^a   Jonas, Will ^a   Kirchhofer, Daniel ^c   Gailani, David ^d   Gruber, Andras ^e   Kasthuri, Raj ^a   Key, Nigel S ^a   Mackman, Nigel ^a   Pawlinski, Rafal ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b MAHIDOL UNIVERSITY   (Thailand)

^c GENENTECH INC   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12A; HEME; HEMOPEXIN; IMMUNOGLOBULIN G; PROCOAGULANT; THROMBIN ANTITHROMBIN COMPLEX; THROMBOPLASTIN; ANTIBODY; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD VESSEL INJURY; BLOOD VESSEL PERMEABILITY; BONE MARROW CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMATOPOIETIC CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LEUKOCYTE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; SICKLE CELL ANEMIA; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; C57BL MOUSE; CAPILLARY PERMEABILITY; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; GENE DELETION; GENE EXPRESSION; GENETICS; HEMOLYTIC ANEMIA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; PIG; TRANSGENIC MOUSE;

ANEMIA, HEMOLYTIC; ANEMIA, SICKLE CELL; ANIMALS; ANTIBODIES; BLOOD COAGULATION; CAPILLARY PERMEABILITY; CELLS, CULTURED; FACTOR XI; FACTOR XIIA; FEMALE; GENE DELETION; GENE EXPRESSION; HEME; HEMOPEXIN; HUMANS; INJECTIONS, INTRAVENOUS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, SMALL INTERFERING; SWINE; THROMBOPLASTIN;

EID: 84924703145     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2014.114728     Document Type: Article

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