메뉴 건너뛰기




Volumn 66, Issue 5, 2015, Pages 639-649

Fibroblast growth factor receptor (FGFR) gene amplifications are rare events in bladder cancer

Author keywords

Amplification; Bladder cancer; FGFR1; FGFR2; FGFR3

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FGFR1 PROTEIN, HUMAN; FGFR2 PROTEIN, HUMAN; FGFR3 PROTEIN, HUMAN;

EID: 84924633293     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/his.12473     Document Type: Article
Times cited : (40)

References (42)
  • 1
    • 84924543339 scopus 로고    scopus 로고
    • Harnblase
    • 9th edn. Berlin: Robert Koch-Institut und die Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V.
    • Kaatsch P, Spix C, Hentschel S et al. Harnblase. In Krebs in Deutschland 2009/2010, 9th edn. Berlin: Robert Koch-Institut und die Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V., 2013; 100-102.
    • (2013) Krebs in Deutschland 2009/2010 , pp. 100-102
    • Kaatsch, P.1    Spix, C.2    Hentschel, S.3
  • 2
    • 84864917826 scopus 로고    scopus 로고
    • A Decade of FGF receptor research in bladder cancer: past, present, and future challenges
    • di Martino E, Tomlinson DC, Knowles MA. A Decade of FGF receptor research in bladder cancer: past, present, and future challenges. Adv. Urol. 2012; 2012; 429213 doi:1155/2012/429213.
    • (2012) Adv. Urol. , vol.2012 , pp. 429213
    • di Martino, E.1    Tomlinson, D.C.2    Knowles, M.A.3
  • 3
    • 0032841519 scopus 로고    scopus 로고
    • Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
    • Cappellen D, De Oliveira C, Ricol D et al. Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat. Genet. 1999; 23; 18-20.
    • (1999) Nat. Genet. , vol.23 , pp. 18-20
    • Cappellen, D.1    De Oliveira, C.2    Ricol, D.3
  • 4
    • 33746376029 scopus 로고    scopus 로고
    • Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder
    • vanOers JMM, Adam C, Denzinger S et al. Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder. Int. J. Cancer 2006; 119; 1212-1215.
    • (2006) Int. J. Cancer , vol.119 , pp. 1212-1215
    • vanOers, J.M.M.1    Adam, C.2    Denzinger, S.3
  • 6
    • 33747079040 scopus 로고    scopus 로고
    • Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas
    • Hernandez S, Lopez-Knowles E, Lloreta J et al. Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas. J. Clin. Oncol. 2006; 24; 3664-3671.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3664-3671
    • Hernandez, S.1    Lopez-Knowles, E.2    Lloreta, J.3
  • 7
    • 0034969685 scopus 로고    scopus 로고
    • Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors
    • Billerey C, Chopin D, Aubriot-Lorton MH et al. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am. J. Pathol. 2001; 158; 1955-1959.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1955-1959
    • Billerey, C.1    Chopin, D.2    Aubriot-Lorton, M.H.3
  • 8
    • 50849086460 scopus 로고    scopus 로고
    • Prediction of progression of non-muscle-invasive bladder cancer by WHO 1973 and 2004 grading and by FGFR3 mutation status: a prospective study
    • Burger M, van der Aa MN, van Oers JM et al. Prediction of progression of non-muscle-invasive bladder cancer by WHO 1973 and 2004 grading and by FGFR3 mutation status: a prospective study. Eur. Urol. 2008; 54; 835-843.
    • (2008) Eur. Urol. , vol.54 , pp. 835-843
    • Burger, M.1    van der Aa, M.N.2    van Oers, J.M.3
  • 9
    • 83555162466 scopus 로고    scopus 로고
    • The FGFR3 mutation is related to favorable pT1 bladder cancer
    • van Rhijn BW, van der Kwast TH, Liu L et al. The FGFR3 mutation is related to favorable pT1 bladder cancer. J. Urol. 2012; 187; 310-314.
    • (2012) J. Urol. , vol.187 , pp. 310-314
    • van Rhijn, B.W.1    van der Kwast, T.H.2    Liu, L.3
  • 10
    • 34548407864 scopus 로고    scopus 로고
    • FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
    • Tomlinson DC, Baldo O, Harnden P, Knowles MA. FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J. Pathol. 2007; 213; 91-98.
    • (2007) J. Pathol. , vol.213 , pp. 91-98
    • Tomlinson, D.C.1    Baldo, O.2    Harnden, P.3    Knowles, M.A.4
  • 11
    • 78650169276 scopus 로고    scopus 로고
    • FGFR3 mutational status and protein expression in patients with bladder cancer in a Jordanian population
    • Bodoor K, Ghabkari A, Jaradat Z et al. FGFR3 mutational status and protein expression in patients with bladder cancer in a Jordanian population. Cancer Epidemiol. 2010; 34; 724-732.
    • (2010) Cancer Epidemiol. , vol.34 , pp. 724-732
    • Bodoor, K.1    Ghabkari, A.2    Jaradat, Z.3
  • 12
    • 66349120144 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen activated protein kinase pathway in bladder cancer
    • Tomlinson DC, Lamont FR, Shnyder SD, Knowles MA. Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen activated protein kinase pathway in bladder cancer. Cancer Res. 2009; 69; 4613-4620.
    • (2009) Cancer Res. , vol.69 , pp. 4613-4620
    • Tomlinson, D.C.1    Lamont, F.R.2    Shnyder, S.D.3    Knowles, M.A.4
  • 13
    • 0035361601 scopus 로고    scopus 로고
    • High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer
    • Simon R, Richter J, Wagner U et al. High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer. Cancer Res. 2001; 61; 4514-4519.
    • (2001) Cancer Res. , vol.61 , pp. 4514-4519
    • Simon, R.1    Richter, J.2    Wagner, U.3
  • 14
    • 0001317018 scopus 로고    scopus 로고
    • Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas
    • de Medina SGD, Chopin D, El Marjou A et al. Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas. Oncogene 1997; 14; 323-330.
    • (1997) Oncogene , vol.14 , pp. 323-330
    • de Medina, S.G.D.1    Chopin, D.2    El Marjou, A.3
  • 15
    • 66349135677 scopus 로고    scopus 로고
    • Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
    • Qing J, Du X, Chen Y et al. Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J. Clin. Invest. 2009; 119; 1216-1229.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1216-1229
    • Qing, J.1    Du, X.2    Chen, Y.3
  • 16
    • 78650875209 scopus 로고    scopus 로고
    • Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo
    • Lamont FR, Tomlinson DC, Cooper PA, Shnyder SD, Chester JD, Knowles MA. Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo. Br. J. Cancer 2011; 104; 75-82.
    • (2011) Br. J. Cancer , vol.104 , pp. 75-82
    • Lamont, F.R.1    Tomlinson, D.C.2    Cooper, P.A.3    Shnyder, S.D.4    Chester, J.D.5    Knowles, M.A.6
  • 17
    • 84884711098 scopus 로고    scopus 로고
    • Small molecule inhibition of fibroblast growth factor receptors in cancer
    • Liang G, Chen G, Wei X, Zhao Y, Li X. Small molecule inhibition of fibroblast growth factor receptors in cancer. Cytokine Growth Factor Rev. 2013; 24; 467-475.
    • (2013) Cytokine Growth Factor Rev. , vol.24 , pp. 467-475
    • Liang, G.1    Chen, G.2    Wei, X.3    Zhao, Y.4    Li, X.5
  • 18
    • 80054900437 scopus 로고    scopus 로고
    • Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamin o]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase
    • Guagnano V, Furet P, Spanka C et al. Discovery of 3-(2, 6-dichloro-3, 5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamin o]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. J. Med. Chem. 2011; 54; 7066-7083.
    • (2011) J. Med. Chem. , vol.54 , pp. 7066-7083
    • Guagnano, V.1    Furet, P.2    Spanka, C.3
  • 22
    • 84868456197 scopus 로고    scopus 로고
    • Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer
    • Schildhaus HU, Heukamp LC, Merkelbach-Bruse S et al. Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer. Mod. Pathol. 2012; 25; 1473-1480.
    • (2012) Mod. Pathol. , vol.25 , pp. 1473-1480
    • Schildhaus, H.U.1    Heukamp, L.C.2    Merkelbach-Bruse, S.3
  • 23
    • 27744600116 scopus 로고    scopus 로고
    • A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine
    • van Oers JM, Lurkin I, van Exsel AJ et al. A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine. Clin. Cancer Res. 2005; 11; 7743-7748.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 7743-7748
    • van Oers, J.M.1    Lurkin, I.2    van Exsel, A.J.3
  • 24
    • 33746754183 scopus 로고    scopus 로고
    • Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi
    • Hafner C, van Oers JM, Vogt T et al. Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J. Clin. Invest. 2006; 116; 2201-2207.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2201-2207
    • Hafner, C.1    van Oers, J.M.2    Vogt, T.3
  • 25
    • 84897022815 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of urothelial bladder carcinoma
    • Cancer Genome Atlas Research Network.
    • Cancer Genome Atlas Research Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014; 507; 315-322.
    • (2014) Nature , vol.507 , pp. 315-322
  • 26
    • 68849111431 scopus 로고    scopus 로고
    • Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis
    • Marchiò C, Lambros MB, Gugliotta P et al. Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis. J. Pathol. 2009; 219; 16-24.
    • (2009) J. Pathol. , vol.219 , pp. 16-24
    • Marchiò, C.1    Lambros, M.B.2    Gugliotta, P.3
  • 27
    • 34447325266 scopus 로고    scopus 로고
    • FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis
    • Elbauomy Elsheikh S, Green AR, Lambros MB et al. FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis. Breast Cancer Res. 2007; 9; R23.
    • (2007) Breast Cancer Res. , vol.9 , pp. R23
    • Elbauomy Elsheikh, S.1    Green, A.R.2    Lambros, M.B.3
  • 28
    • 70350536585 scopus 로고    scopus 로고
    • Distinct microRNA alterations characterize high- and low-grade bladder cancer
    • Catto JW, Miah S, Owen HC et al. Distinct microRNA alterations characterize high- and low-grade bladder cancer. Cancer Res. 2009; 69; 8472-8481.
    • (2009) Cancer Res. , vol.69 , pp. 8472-8481
    • Catto, J.W.1    Miah, S.2    Owen, H.C.3
  • 29
    • 77952243279 scopus 로고    scopus 로고
    • In situ detection and genotyping of individual mRNA molecules
    • Larsson C, Grundberg I, Söderberg O et al. In situ detection and genotyping of individual mRNA molecules. Nat. Methods 2010; 7; 395-397.
    • (2010) Nat. Methods , vol.7 , pp. 395-397
    • Larsson, C.1    Grundberg, I.2    Söderberg, O.3
  • 30
    • 74949112352 scopus 로고    scopus 로고
    • Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma
    • Nord H, Segersten U, Sandgren J et al. Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma. Int. J. Cancer 2010; 126; 1390-1402.
    • (2010) Int. J. Cancer , vol.126 , pp. 1390-1402
    • Nord, H.1    Segersten, U.2    Sandgren, J.3
  • 31
    • 84875960641 scopus 로고    scopus 로고
    • Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value
    • Chekaluk Y, Wu CL, Rosenberg J et al. Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value. PLoS ONE 2013; 8; e60927.
    • (2013) PLoS ONE , vol.8 , pp. e60927
    • Chekaluk, Y.1    Wu, C.L.2    Rosenberg, J.3
  • 32
    • 84890134222 scopus 로고    scopus 로고
    • 6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer
    • Shen H, Morrison CD, Zhang J et al. 6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer. Oncotarget 2013; 4; 2124-2134.
    • (2013) Oncotarget , vol.4 , pp. 2124-2134
    • Shen, H.1    Morrison, C.D.2    Zhang, J.3
  • 33
    • 84880944047 scopus 로고    scopus 로고
    • Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA
    • López V, González-Peramato P, Suela J et al. Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA. J. Transl. Med. 2013; 11; 182.
    • (2013) J. Transl. Med. , vol.11 , pp. 182
    • López, V.1    González-Peramato, P.2    Suela, J.3
  • 34
    • 84883507940 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization analysis of CCND3 gene as marker of progression in bladder carcinoma
    • Beltran AL, Ordonez JL, Otero AP et al. Fluorescence in situ hybridization analysis of CCND3 gene as marker of progression in bladder carcinoma. J. Biol. Regul. Homeost. Agents 2013; 27; 559-567.
    • (2013) J. Biol. Regul. Homeost. Agents , vol.27 , pp. 559-567
    • Beltran, A.L.1    Ordonez, J.L.2    Otero, A.P.3
  • 35
    • 84874655203 scopus 로고    scopus 로고
    • Her2 amplification distinguishes a subset of non-muscle-invasive bladder cancers with a high risk of progression
    • Chen PC, Yu HJ, Chang YH, Pan CC. Her2 amplification distinguishes a subset of non-muscle-invasive bladder cancers with a high risk of progression. J. Clin. Pathol. 2013; 66; 113-119.
    • (2013) J. Clin. Pathol. , vol.66 , pp. 113-119
    • Chen, P.C.1    Yu, H.J.2    Chang, Y.H.3    Pan, C.C.4
  • 36
    • 77951471947 scopus 로고    scopus 로고
    • Assessing HER2 gene amplification as a potential target for therapy in invasive urothelial bladder cancer with a standardized methodology: results in 1005 patients
    • Laé M, Couturier J, Oudard S et al. Assessing HER2 gene amplification as a potential target for therapy in invasive urothelial bladder cancer with a standardized methodology: results in 1005 patients. Ann. Oncol. 2010; 21; 815-819.
    • (2010) Ann. Oncol. , vol.21 , pp. 815-819
    • Laé, M.1    Couturier, J.2    Oudard, S.3
  • 37
    • 79959556990 scopus 로고    scopus 로고
    • Her2 amplification is significantly more frequent in lymph node metastases from urothelial bladder cancer than in the primary tumours
    • Fleischmann A, Rotzer D, Seiler R, Studer UE, Thalmann GN. Her2 amplification is significantly more frequent in lymph node metastases from urothelial bladder cancer than in the primary tumours. Eur. Urol. 2011; 60; 350-357.
    • (2011) Eur. Urol. , vol.60 , pp. 350-357
    • Fleischmann, A.1    Rotzer, D.2    Seiler, R.3    Studer, U.E.4    Thalmann, G.N.5
  • 39
    • 84921678806 scopus 로고    scopus 로고
    • A phase I trial of LY2874455, a fibroblast growth factor receptor inhibitor, in patients with advanced cancer [Abstract]
    • San Diego, CA. Philadelphia (PA): AACR, Abstract no. CT215.
    • Tie J, Bang Y-J, Park YS et al. A phase I trial of LY2874455, a fibroblast growth factor receptor inhibitor, in patients with advanced cancer [Abstract]. In Proceedings of the 105th Annual Meeting of the American Association for Cancer Research, 5-9 April 2014. San Diego, CA. Philadelphia (PA): AACR; 2014. Abstract no. CT215.
    • (2014) Proceedings of the 105th Annual Meeting of the American Association for Cancer Research, 5-9 April 2014
    • Tie, J.1    Bang, Y.-J.2    Park, Y.S.3
  • 40
    • 84873347374 scopus 로고    scopus 로고
    • The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma
    • Parker BC, Annala MJ, Cogdell DE et al. The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. J. Clin. Invest. 2013; 123; 855-865.
    • (2013) J. Clin. Invest. , vol.123 , pp. 855-865
    • Parker, B.C.1    Annala, M.J.2    Cogdell, D.E.3
  • 41
    • 84878781242 scopus 로고    scopus 로고
    • Identification of targetable FGFR gene fusions in diverse cancers
    • Wu YM, Su F, Kalyana-Sundaram S et al. Identification of targetable FGFR gene fusions in diverse cancers. Cancer Discov. 2013; 3; 636-647.
    • (2013) Cancer Discov. , vol.3 , pp. 636-647
    • Wu, Y.M.1    Su, F.2    Kalyana-Sundaram, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.