메뉴 건너뛰기




Volumn , Issue , 2012, Pages

A decade of FGF receptor research in bladder cancer: Past, present, and future challenges

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84864917826     PISSN: 16876369     EISSN: 16876377     Source Type: Journal    
DOI: 10.1155/2012/429213     Document Type: Review
Times cited : (111)

References (93)
  • 5
    • 80755172266 scopus 로고    scopus 로고
    • A review of current guidelines and best practice recommendations for the management of nonmuscle invasive bladder cancer by the international bladder cancer group
    • Brausi M., Witjes J. A., Lamm D., Persad R., Palou J., A review of current guidelines and best practice recommendations for the management of nonmuscle invasive bladder cancer by the international bladder cancer group The Journal of Urology 2011 186 6 2158 2167
    • (2011) The Journal of Urology , vol.186 , Issue.6 , pp. 2158-2167
    • Brausi, M.1    Witjes, J.A.2    Lamm, D.3    Persad, R.4    Palou, J.5
  • 6
    • 0346100499 scopus 로고    scopus 로고
    • The health economics of bladder cancer: A comprehensive review of the published literature
    • Botteman M. F., Pashos C. L., Redaelli A., Laskin B., Hauser R., The health economics of bladder cancer: A comprehensive review of the published literature Pharmacoeconomics 2003 21 18 1315 1330 (Pubitemid 38041357)
    • (2003) PharmacoEconomics , vol.21 , Issue.18 , pp. 1315-1330
    • Botteman, M.F.1    Pashos, C.L.2    Redaelli, A.3    Laskin, B.4    Hauser, R.5
  • 8
    • 0036828099 scopus 로고    scopus 로고
    • Bladder cancer: Epidemiology, diagnosis, and management
    • DOI 10.1046/j.1523-5394.2002.106011.x
    • Pashos C. L., Botteman M. F., Laskin B. L., Redaelli A., Bladder cancer: epidemiology, diagnosis, and management Cancer Practice 2002 10 6 311 322 (Pubitemid 35231626)
    • (2002) Cancer Practice , vol.10 , Issue.6 , pp. 311-322
    • Pashos, C.L.1    Botteman, M.F.2    Laskin, B.L.3    Redaelli, A.4
  • 9
    • 32944465832 scopus 로고    scopus 로고
    • Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: A combined analysis of 2596 patients from seven EORTC trials
    • DOI 10.1016/j.eururo.2005.12.031, PII S0302283805008523
    • Sylvester R. J., van Der Meijden A. P. M., Oosterlinck W., Witjes J. A., Bouffioux C., Denis L., Newling D. W. W., Kurth K., Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: A combined analysis of 2596 patients from seven EORTC trials European Urology 2006 49 3 466 475 (Pubitemid 43259554)
    • (2006) European Urology , vol.49 , Issue.3 , pp. 466-475
    • Sylvester, R.J.1    Van Der Meijden, A.P.M.2    Oosterlinck, W.3    Witjes, J.A.4    Bouffioux, C.5    Denis, L.6    Newling, D.W.W.7    Kurth, K.8
  • 10
    • 0028049182 scopus 로고
    • The influence of review pathology on study outcome of a randomized multicentre bladder cancer trial
    • Witjes J. A., Kiemeney L. A. L. M., Schaafsma H. E., Debruyene F. M. J., The influence of review pathology on study outcome of a randomized multicentre bladder cancer trial British Journal of Urology 1994 73 2 172 176 (Pubitemid 24057665)
    • (1994) British Journal of Urology , vol.73 , Issue.2 , pp. 172-176
    • Witjes, J.A.1    Kiemeney, L.A.L.M.2    Schaafsma, H.E.3    Debruyene, F.M.J.4
  • 12
    • 13444263240 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling during early vertebrate development
    • DOI 10.1210/er.2003-0040
    • Bttcher R. T., Niehrs C., Fibroblast growth factor signaling during early vertebrate development Endocrine Reviews 2005 26 1 63 77 (Pubitemid 40209387)
    • (2005) Endocrine Reviews , vol.26 , Issue.1 , pp. 63-77
    • Bottcher, R.T.1    Niehrs, C.2
  • 13
  • 14
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: Biology, pathophysiology and therapy
    • Beenken A., Mohammadi M., The FGF family: biology, pathophysiology and therapy Nature Reviews Drug Discovery 2009 8 3 235 253
    • (2009) Nature Reviews Drug Discovery , vol.8 , Issue.3 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 16
    • 0033556802 scopus 로고    scopus 로고
    • Signal transduction by fibroblast growth factor receptors
    • Klint P., Claesson-Welsh L., Signal transduction by fibroblast growth factor receptors Frontiers in Bioscience 1999 4 D165 D177
    • (1999) Frontiers in Bioscience , vol.4
    • Klint, P.1    Claesson-Welsh, L.2
  • 18
    • 33744937606 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family: The complete mammalian FGF family
    • DOI 10.1074/jbc.M601252200
    • Zhang X., Ibrahimi O. A., Olsen S. K., Umemori H., Mohammadi M., Ornitz D. M., Receptor specificity of the fibroblast growth factor family: the complete mammalian FGF family The Journal of Biological Chemistry 2006 281 23 15694 15700 (Pubitemid 43848456)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.23 , pp. 15694-15700
    • Zhang, X.1    Ibrahimi, O.A.2    Olsen, S.K.3    Umemori, H.4    Mohammadi, M.5    Ornitz, D.M.6
  • 19
    • 0028239789 scopus 로고
    • Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1
    • Chellaiah A. T., McEwen D. G., Werner S., Xu J., Ornitz D. M., Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1 The Journal of Biological Chemistry 1994 269 15 11620 11627 (Pubitemid 24200387)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.15 , pp. 11620-11627
    • Chellaiah, A.T.1    McEwen, D.G.2    Werner, S.3    Xu, J.4    Ornitz, D.M.5
  • 20
    • 0028986809 scopus 로고
    • Alternately spliced NH 2 -terminal immunoglobulin-like loop i in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1
    • Wang F., Kan M., Yan G., Xu J., McKeehan W. L., Alternately spliced NH 2 -terminal immunoglobulin-like loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1 The Journal of Biological Chemistry 1995 270 17 10231 10235
    • (1995) The Journal of Biological Chemistry , vol.270 , Issue.17 , pp. 10231-10235
    • Wang, F.1    Kan, M.2    Yan, G.3    Xu, J.4    McKeehan, W.L.5
  • 21
    • 0034118339 scopus 로고    scopus 로고
    • Normal human fibroblasts produce membrane-bound and soluble isoforms of FGFR-1
    • DOI 10.1006/mcbr.2000.0199
    • Root L. L., Shipley G. D., Normal human fibroblasts produce membrane-bound and soluble isoforms of FGFR-1 Molecular Cell Biology Research Communications 2000 3 2 87 97 (Pubitemid 30252134)
    • (2000) Molecular Cell Biology Research Communications , vol.3 , Issue.2 , pp. 87-97
    • Root, L.L.1    Shipley, G.D.2
  • 22
    • 0035200948 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs
    • DOI 10.1006/mcbr.2001.0306
    • Terada M., Shimizu A., Sato N., Miyakaze S. I., Katayama H., Kurokawa-Seo M., Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs Molecular Cell Biology Research Communications 2001 4 6 365 373 (Pubitemid 33098108)
    • (2001) Molecular Cell Biology Research Communications , vol.4 , Issue.6 , pp. 365-373
    • Terada, M.1    Shimizu, A.2    Sato, N.3    Miyakaze, S.-I.4    Katayama, H.5    Kurokawa-Seo, M.6
  • 24
    • 79953718346 scopus 로고    scopus 로고
    • Biology of FGFRL1, the fifth fibroblast growth factor receptor
    • Trueb B., Biology of FGFRL1, the fifth fibroblast growth factor receptor Cellular and Molecular Life Sciences 2011 68 6 951 964
    • (2011) Cellular and Molecular Life Sciences , vol.68 , Issue.6 , pp. 951-964
    • Trueb, B.1
  • 25
    • 0032841519 scopus 로고    scopus 로고
    • Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas [3]
    • DOI 10.1038/12615
    • Bourdin J., Sastre-Garau X., Chopin D., Thiery J. P., Radvanyi F., Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas Nature Genetics 1999 23 1 18 20 (Pubitemid 29418781)
    • (1999) Nature Genetics , vol.23 , Issue.1 , pp. 18-20
    • Bourdin, J.1    Sastre-Garau, X.2    Chopin, D.3    Thiery, J.P.4    Radvanyi, F.5
  • 26
    • 0035825598 scopus 로고    scopus 로고
    • Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma
    • DOI 10.1038/sj.onc.1204110
    • Sibley K., Cuthbert-Heavens D., Knowles M. A., Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma Oncogene 2001 20 6 686 691 (Pubitemid 32179337)
    • (2001) Oncogene , vol.20 , Issue.6 , pp. 686-691
    • Sibley, K.1    Cuthbert-Heavens, D.2    Knowles, M.A.3
  • 32
    • 34548407864 scopus 로고    scopus 로고
    • FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
    • DOI 10.1002/path.2207
    • Tomlinson D. C., Baldo O., Hamden P., Knowles M. A., FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer The Journal of Pathology 2007 213 1 91 98 (Pubitemid 47354570)
    • (2007) Journal of Pathology , vol.213 , Issue.1 , pp. 91-98
    • Tomlinson, D.C.1    Baldo, O.2    Hamden, P.3    Knowles, M.A.4
  • 33
    • 0036239904 scopus 로고    scopus 로고
    • Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization
    • Adar R., Monsonego-Ornan E., David P., Yayon A., Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization Journal of Bone and Mineral Research 2002 17 5 860 868 (Pubitemid 34441903)
    • (2002) Journal of Bone and Mineral Research , vol.17 , Issue.5 , pp. 860-868
    • Adar, R.1    Monsonego-Ornan, E.2    David, P.3    Yayon, A.4
  • 34
    • 0031985174 scopus 로고    scopus 로고
    • Constitutive activation of fibroblast growth factor receptor 3 by mutations responsible for the lethal skeletal dysplasia thanatophoric dysplasia type I
    • D'Avis P. Y., Robertson S. C., Meyer A. N., Bardwell W. M., Webster M. K., Donoghue D. J., Constitutive activation of fibroblast growth factor receptor 3 by mutations responsible for the lethal skeletal dysplasia thanatophoric dysplasia type I Cell Growth and Differentiation 1998 9 1 71 78 (Pubitemid 28049529)
    • (1998) Cell Growth and Differentiation , vol.9 , Issue.1 , pp. 71-78
    • D'Avis, P.Y.1    Robertson, S.C.2    Meyer, A.N.3    Bardwell, W.M.4    Webster, M.K.5    Donoghue, D.J.6
  • 36
    • 0029945085 scopus 로고    scopus 로고
    • Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II
    • Webster M. K., D'Avis P. Y., Robertson S. C., Donoghue D. J., Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II Molecular and Cellular Biology 1996 16 8 4081 4087 (Pubitemid 26251207)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.8 , pp. 4081-4087
    • Webster, M.K.1    D'Avis, P.Y.2    Robertson, S.C.3    Donoghue, D.J.4
  • 37
    • 33644956734 scopus 로고    scopus 로고
    • K644E/M FGFR3 mutants activate Erk1/2 from the endoplasmic reticulum through FRS2 and PLC -independent pathways
    • Lievens P. M. J., Roncador A., Liboi E., K644E/M FGFR3 mutants activate Erk1/2 from the endoplasmic reticulum through FRS2 and PLC -independent pathways Journal of Molecular Biology 2006 357 3 783 792
    • (2006) Journal of Molecular Biology , vol.357 , Issue.3 , pp. 783-792
    • Lievens, P.M.J.1    Roncador, A.2    Liboi, E.3
  • 38
    • 28544435982 scopus 로고    scopus 로고
    • Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor-induced proliferation and is repressed in urothelial carcinoma cell lines
    • DOI 10.1158/0008-5472.CAN-05-1718
    • Tomlinson D. C., L'Hte C. G., Kennedy W., Pitt E., Knowles M. A., Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor-induced proliferation and is repressed in urothelial carcinoma cell lines Cancer Research 2005 65 22 10441 10449 (Pubitemid 41743738)
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10441-10449
    • Tomlinson, D.C.1    L'Hote, C.G.2    Kennedy, W.3    Pitt, E.4    Knowles, M.A.5
  • 39
    • 0035889913 scopus 로고    scopus 로고
    • The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas
    • DOI 10.1002/1097-0142 (20011115)92:10< 2555::AID-CNCR1607>3.0.CO;2- M
    • Kimura T., Suzuki H., Ohashi T., Asano K., Kiyota H., The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas Cancer 2001 92 10 2555 2561 (Pubitemid 33049438)
    • (2001) Cancer , vol.92 , Issue.10 , pp. 2555-2561
    • Kimura, T.1    Suzuki, H.2    Ohashi, T.3    Asano, K.4    Kiyota, H.5    Eto, Y.6
  • 41
    • 0035866380 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate
    • Van Rhijn B. W. G., Lurkin I., Radvanyi F., Kirkels W. J., van Der Kwast T. H., Zwarthoff E. C., The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate Cancer Research 2001 61 4 1265 1268 (Pubitemid 34292538)
    • (2001) Cancer Research , vol.61 , Issue.4 , pp. 1265-1268
    • Van Rhijn, B.W.G.1    Lurkin, I.2    Radvanyi, F.3    Kirkels, W.J.4    Van Der Kwast, T.H.5    Zwarthoff, E.C.6
  • 44
    • 0030922231 scopus 로고    scopus 로고
    • Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3
    • DOI 10.1038/ng0797-260
    • Chesi M., Nardini E., Brents L. A., Schrock E., Ried T., Kuehl W. M., Bergsagel P. L., Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3 Nature Genetics 1997 16 3 260 264 (Pubitemid 27280209)
    • (1997) Nature Genetics , vol.16 , Issue.3 , pp. 260-264
    • Chesi, M.1    Nardini, E.2    Brents, L.A.3    Schrock, E.4    Ried, T.5    Kuehl, W.M.6    Bergsagel, P.L.7
  • 46
    • 0035913187 scopus 로고    scopus 로고
    • Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours
    • DOI 10.1038/sj.onc.1204543
    • Sibley K., Stern P., Knowles M. A., Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours Oncogene 2001 20 32 4416 4418 (Pubitemid 32726885)
    • (2001) Oncogene , vol.20 , Issue.32 , pp. 4416-4418
    • Sibley, K.1    Stern, P.2    Knowles, M.A.3
  • 49
    • 71349085679 scopus 로고    scopus 로고
    • Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type-and mutation-specific manner
    • Di Martino E., L'Hote C. G., Kennedy W., Tomlinson D. C., Knowles M. A., Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type-and mutation-specific manner Oncogene 2009 28 48 4306 4316
    • (2009) Oncogene , vol.28 , Issue.48 , pp. 4306-4316
    • Di Martino, E.1    L'Hote, C.G.2    Kennedy, W.3    Tomlinson, D.C.4    Knowles, M.A.5
  • 51
    • 17844402791 scopus 로고    scopus 로고
    • Bad bones, absent smell, selfish testes: The pleiotropic consequences of human FGF receptor mutations
    • DOI 10.1016/j.cytogfr.2005.03.001
    • Wilkie A. O. M., Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations Cytokine and Growth Factor Reviews 2005 16 2 187 203 (Pubitemid 40616116)
    • (2005) Cytokine and Growth Factor Reviews , vol.16 , Issue.2 SPEC. ISSUE , pp. 187-203
    • Wilkie, A.O.M.1
  • 52
    • 16544376302 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions
    • Matsumoto M., Ohtsuki Y., Ochii K., Seike Y., Iseda N., Sasaki T., Okada Y., Kurabayashi A., Furihata M., Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions Oncology Reports 2004 12 5 967 971
    • (2004) Oncology Reports , vol.12 , Issue.5 , pp. 967-971
    • Matsumoto, M.1    Ohtsuki, Y.2    Ochii, K.3    Seike, Y.4    Iseda, N.5    Sasaki, T.6    Okada, Y.7    Kurabayashi, A.8    Furihata, M.9
  • 54
    • 33644841931 scopus 로고    scopus 로고
    • Genetic alterations in urothelial bladder carcinoma: An updated review
    • DOI 10.1002/cncr.21743
    • Mhawech-Fauceglia P., Cheney R. T., Schwaller J., Genetic alterations in urothelial bladder carcinoma: An updated review Cancer 2006 106 6 1205 1216 (Pubitemid 43363896)
    • (2006) Cancer , vol.106 , Issue.6 , pp. 1205-1216
    • Mhawech-Fauceglia, P.1    Cheney, R.T.2    Schwaller, J.3
  • 58
    • 0032954333 scopus 로고    scopus 로고
    • Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer
    • Giri D., Ropiquet F., Ittmann M., Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer Clinical Cancer Research 1999 5 5 1063 1071 (Pubitemid 29233220)
    • (1999) Clinical Cancer Research , vol.5 , Issue.5 , pp. 1063-1071
    • Giri, D.1    Ropiquet, F.2    Ittmann, M.3
  • 62
    • 0036045381 scopus 로고    scopus 로고
    • Tyrosine kinase fusion genes in chronic myeloproliferative diseases
    • Cross N. C. P., Reiter A., Tyrosine kinase fusion genes in chronic myeloproliferative diseases Leukemia 2002 16 7 1207 1212
    • (2002) Leukemia , vol.16 , Issue.7 , pp. 1207-1212
    • Cross, N.C.P.1    Reiter, A.2
  • 64
    • 0345734275 scopus 로고    scopus 로고
    • Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice
    • Freeman K. W., Welm B. E., Gangula R. D., Rosen J. M., Ittmann M., Greenberg N. M., Spencer D. M., Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice Cancer Research 2003 63 23 8256 8263 (Pubitemid 37549476)
    • (2003) Cancer Research , vol.63 , Issue.23 , pp. 8256-8263
    • Freeman, K.W.1    Welm, B.E.2    Gangula, R.D.3    Rosen, J.M.4    Ittmann, M.5    Greenberg, N.M.6    Spencer, D.M.7
  • 65
    • 0141885098 scopus 로고    scopus 로고
    • Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation
    • Freeman K. W., Gangula R. D., Welm B. E., Ozen M., Foster B. A., Rosen J. M., Ittmann M., Greenberg N. M., Spencer D. M., Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation Cancer Research 2003 63 19 6237 6243 (Pubitemid 37255169)
    • (2003) Cancer Research , vol.63 , Issue.19 , pp. 6237-6243
    • Freeman, K.W.1    Gangula, R.D.2    Welm, B.E.3    Ozen, M.4    Foster, B.A.5    Rosen, J.M.6    Ittmann, M.7    Greenberg, N.M.8    Spencer, D.M.9
  • 66
    • 0037071550 scopus 로고    scopus 로고
    • Inducible dimerization of FGFR1: Development of a mouse model to analyze progressive transformation of the mammary gland
    • DOI 10.1083/jcb.200107119
    • Welm B. E., Freeman K. W., Chen M., Contreras A., Spencer D. M., Rosen J. M., Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland Journal of Cell Biology 2002 157 4 703 714 (Pubitemid 34839797)
    • (2002) Journal of Cell Biology , vol.157 , Issue.4 , pp. 703-714
    • Welm, B.E.1    Freeman, K.W.2    Chen, M.3    Contreras, A.4    Spencer, D.M.5    Rosen, J.M.6
  • 67
    • 36649025928 scopus 로고    scopus 로고
    • Inducible FGFR-1 Activation Leads to Irreversible Prostate Adenocarcinoma and an Epithelial-to-Mesenchymal Transition
    • DOI 10.1016/j.ccr.2007.11.004, PII S1535610807003352
    • Acevedo V. D., Gangula R. D., Freeman K. W., Li R., Zhang Y., Wang F., Ayala G. E., Peterson L. E., Ittmann M., Spencer D. M., Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition Cancer Cell 2007 12 6 559 571 (Pubitemid 350199071)
    • (2007) Cancer Cell , vol.12 , Issue.6 , pp. 559-571
    • Acevedo, V.D.1    Gangula, R.D.2    Freeman, K.W.3    Li, R.4    Zhang, Y.5    Wang, F.6    Ayala, G.E.7    Peterson, L.E.8    Ittmann, M.9    Spencer, D.M.10
  • 68
    • 66349120144 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer
    • Tomlinson D. C., Lamont F. R., Shnyder S. D., Knowles M. A., Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer Cancer Research 2009 69 11 4613 4620
    • (2009) Cancer Research , vol.69 , Issue.11 , pp. 4613-4620
    • Tomlinson, D.C.1    Lamont, F.R.2    Shnyder, S.D.3    Knowles, M.A.4
  • 69
    • 78149318726 scopus 로고    scopus 로고
    • Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer
    • Tomlinson D. C., Knowles M. A., Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer American The Journal of Pathology 2010 177 5 2379 2386
    • (2010) American the Journal of Pathology , vol.177 , Issue.5 , pp. 2379-2386
    • Tomlinson, D.C.1    Knowles, M.A.2
  • 73
    • 34548386127 scopus 로고    scopus 로고
    • Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer
    • Tomlinson D. C., Hurst C. D., Knowles M. A., Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer Oncogene 2007 26 40 5889 5899
    • (2007) Oncogene , vol.26 , Issue.40 , pp. 5889-5899
    • Tomlinson, D.C.1    Hurst, C.D.2    Knowles, M.A.3
  • 75
    • 24344461320 scopus 로고    scopus 로고
    • Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation
    • DOI 10.1158/1078-0432.CCR-05-0282
    • Martnez-Torrecuadrada J., Cifuentes G., López-Serra P., Saenz P., Martnez A., Casal J. I., Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation Clinical Cancer Research 2005 11 17 6280 6290 (Pubitemid 41262959)
    • (2005) Clinical Cancer Research , vol.11 , Issue.17 , pp. 6280-6290
    • Martinez-Torrecuadrada, J.1    Cifuentes, G.2    Lopez-Serra, P.3    Saenz, P.4    Martinez, A.5    Casal, J.I.6
  • 76
    • 84862203852 scopus 로고    scopus 로고
    • FGFR1-induced epithelial to mesenchymal transition through MAPK/PLC /COX-2-mediated mechanisms
    • Tomlison D. C., Baxter E. W., Loadman et al. P. M., FGFR1-induced epithelial to mesenchymal transition through MAPK/PLC /COX-2-mediated mechanisms Plos ONE 2012 7 6
    • (2012) Plos ONE , vol.7 , Issue.6
    • Tomlison, D.C.1    Baxter, E.W.2    Loadman, P.M.3
  • 77
    • 27744600116 scopus 로고    scopus 로고
    • A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine
    • DOI 10.1158/1078-0432.CCR-05-1045
    • van Oers J. M. M., Lurkin I., van Exsel A. J. A., Nijsen Y., Van Rhijn B. W. G., van Der Aa M. N. M., Zwarthoff E. C., A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine Clinical Cancer Research 2005 11 21 7743 7748 (Pubitemid 41611617)
    • (2005) Clinical Cancer Research , vol.11 , Issue.21 , pp. 7743-7748
    • Van Oers, J.M.M.1    Lurkin, I.2    Van Exsel, A.J.A.3    Nijsen, Y.4    Van Rhijn, B.W.G.5    Van Der Aa, M.N.M.6    Zwarthoff, E.C.7
  • 78
    • 79960187684 scopus 로고    scopus 로고
    • Optimization of nonmuscle invasive bladder cancer recurrence detection using a urine based FGFR3 mutation assay
    • Zuiverloon T. C. M., Tjin S. S., Busstra M., Bangma C. H., Boevé E. R., Zwarthoff E. C., Optimization of nonmuscle invasive bladder cancer recurrence detection using a urine based FGFR3 mutation assay Journal of Urology 2011 186 2 707 712
    • (2011) Journal of Urology , vol.186 , Issue.2 , pp. 707-712
    • Zuiverloon, T.C.M.1    Tjin, S.S.2    Busstra, M.3    Bangma, C.H.4    Boevé, E.R.5    Zwarthoff, E.C.6
  • 79
    • 78149483788 scopus 로고    scopus 로고
    • FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy
    • Kompier L. C., Lurkin I., van Der Aa M. N. M., Van Rhijn B. W. G., van Der Kwast T. H., Zwarthoff E. C., FGFR3, HRAS, KRAS, NRAS AND PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy PLoS ONE 2010 5 11
    • (2010) PLoS ONE , vol.5 , Issue.11
    • Kompier, L.C.1    Lurkin, I.2    Van Der Aa, M.N.M.3    Van Rhijn, B.W.G.4    Van Der Kwast, T.H.5    Zwarthoff, E.C.6
  • 80
    • 78149395455 scopus 로고    scopus 로고
    • Feasibility study of screening for bladder cancer with urinary molecular markers (the BLU-P project)
    • Roobol M. J., Bangma C. H., el Bouazzaoui S., Franken-Raab C. G., Zwarthoff E. C., Feasibility study of screening for bladder cancer with urinary molecular markers (the BLU-P project) Urologic Oncology 2010 28 6 686 690
    • (2010) Urologic Oncology , vol.28 , Issue.6 , pp. 686-690
    • Roobol, M.J.1    Bangma, C.H.2    El Bouazzaoui, S.3    Franken-Raab, C.G.4    Zwarthoff, E.C.5
  • 81
  • 85
    • 84864917446 scopus 로고    scopus 로고
    • The prognostic value of FGFR3 mutational status for disease recurrence and progression depends on allelic losses at 9p22
    • Ploussard G., Soliman H., Dubosq F., Meria P., Verine J., The prognostic value of FGFR3 mutational status for disease recurrence and progression depends on allelic losses at 9p22 American Journal of Cancer Research 2011 1 4 498 507
    • (2011) American Journal of Cancer Research , vol.1 , Issue.4 , pp. 498-507
    • Ploussard, G.1    Soliman, H.2    Dubosq, F.3    Meria, P.4    Verine, J.5
  • 88
    • 0030945871 scopus 로고    scopus 로고
    • Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
    • DOI 10.1126/science.276.5314.955
    • Mohammadi M., McMahon G., Sun L., Tang C., Hirth P., Yeh B. K., Hubbard S. R., Schlessinger J., Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors Science 1997 276 5314 955 960 (Pubitemid 27209095)
    • (1997) Science , vol.276 , Issue.5314 , pp. 955-960
    • Mohammadi, M.1    McMahon, G.2    Sun, L.3    Tang, C.4    Hirth, P.5    Yeh, B.K.6    Hubbard, S.R.7    Schlessinger, J.8
  • 89
    • 77249137893 scopus 로고    scopus 로고
    • 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino) -pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G 1 /G 0 arrest
    • Miyake M., Ishii M., Koyama N., Kawashima K., Kodama T., Anai S., Fujimoto K., Hirao Y., Sugano K., 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4- diethylamino-butylamino) -pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G 1 /G 0 arrest Journal of Pharmacology and Experimental Therapeutics 2010 332 3 795 802
    • (2010) Journal of Pharmacology and Experimental Therapeutics , vol.332 , Issue.3 , pp. 795-802
    • Miyake, M.1    Ishii, M.2    Koyama, N.3    Kawashima, K.4    Kodama, T.5    Anai, S.6    Fujimoto, K.7    Hirao, Y.8    Sugano, K.9
  • 91
    • 79955667838 scopus 로고    scopus 로고
    • Targeting mutant fibroblast growth factor receptors in cancer
    • Greulich H., Pollock P. M., Targeting mutant fibroblast growth factor receptors in cancer Trends in Molecular Medicine 2011 17 5 283 292
    • (2011) Trends in Molecular Medicine , vol.17 , Issue.5 , pp. 283-292
    • Greulich, H.1    Pollock, P.M.2
  • 92
    • 2142714017 scopus 로고    scopus 로고
    • Monoclonal antibodies as therapeutic agents for cancer
    • DOI 10.1016/S1470-2045(04)01467-6, PII S1470204504014676
    • Harris M., Monoclonal antibodies as therapeutic agents for cancer The Lancet Oncology 2004 5 5 292 302 (Pubitemid 38541581)
    • (2004) Lancet Oncology , vol.5 , Issue.5 , pp. 292-302
    • Harris, M.1
  • 93
    • 42249103255 scopus 로고    scopus 로고
    • Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis
    • DOI 10.1158/1535-7163.MCT-07-0394
    • Martnez-Torrecuadrada J. L., Cheung L. H., López-Serra P., Barderas R., Caamero M., Ferreiro S., Rosenblum M. G., Casal J. I., Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis Molecular Cancer Therapeutics 2008 7 4 862 873 (Pubitemid 351551039)
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.4 , pp. 862-873
    • Martinez-Torrecuadrada, J.L.1    Cheung, L.H.2    Lopez-Serra, P.3    Barderas, R.4    Canamero, M.5    Ferreiro, S.6    Rosenblum, M.G.7    Casal, J.I.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.