Effects of vitamin D on plasma lipid profiles in statin-treated patients with hypercholesterolemia: A randomized placebo-controlled trial

Clinical Nutrition

Volumn 34, Issue 2, 2015, Pages 201-206

  Qin, Xiao Fei ^a   Zhao, Luo Sha ^a   Chen, Wei Ren ^b   Yin, Da Wei ^b   Wang, Hao ^b  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Adjuvant therapy; Hypercholesterolemia; Supplementation; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; ATORVASTATIN; CHOLESTEROL; FLUINDOSTATIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; ROSUVASTATIN; SIMVASTATIN; TRIACYLGLYCEROL; VITAMIN D; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT;

ADD ON THERAPY; ADJUVANT THERAPY; AGED; ARTICLE; CHINA; CHOLESTEROL BLOOD LEVEL; CONSTIPATION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; RANDOMIZED CONTROLLED TRIAL; TRIACYLGLYCEROL BLOOD LEVEL; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; BLOOD; DIET SUPPLEMENTATION; FOLLOW UP; MIDDLE AGED; TREATMENT OUTCOME;

AGED; ANTICHOLESTEREMIC AGENTS; CHOLESTEROL; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; MALE; MIDDLE AGED; TREATMENT OUTCOME; TRIGLYCERIDES; VITAMIN D;

EID: 84924616236     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2014.04.017     Document Type: Article

References (35)

1. Kendrick J., Targher G., Smits G., Chonchol M. 25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey. Atherosclerosis 2009, 205:255-260.
2. Botella-Carretero J.I., Alvarez-Blasco F., Villafruela J.J., Balsa J.A., Vázquez C., Escobar-Morreale H.F. Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity. Clin Nutr 2007, 26:573-580.
3. Schwartz J.B. Effects of vitamin D supplementation in atorvastatin-treated patients: a new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009, 85:198-203.
4. Skaaby T., Husemoen L.L., Pisinger C., Jørgensen T., Thuesen B.H., Fenger M., et al. Vitamin D status and changes in cardiovascular risk factors: a prospective study of a general population. Cardiology. 2012, 123:62-70.
5. 3 supplementation has no effect on conventional cardiovascular risk factors: a parallel-group, double-blind, placebo-controlled RCT. JClin Endocrinol Metab 2012, 97:3557-3568.
6. Ponda M.P., Dowd K., Finkielstein D., Holt P.R., Breslow J.L. The short-term effects of vitamin D repletion on cholesterol: a randomized, placebo-controlled trial. Arterioscler Thromb Vasc Biol 2012, 32:2510-2515.
7. Zhou L., Conner K.R., Caine E.D., Xiao S., Xu L., Gong Y., et al. Epidemiology of alcohol use in rural men in two provinces of China. JStud Alcohol Drugs 2011, 72:333-340.
8. Levey A.S., Stevens L.A., Schmid C.H., Zhang Y.L., Castro A.F., Feldman H.I., et al. Anew equation to estimate glomerular filtration rate. Ann Intern Med 2009, 150:604-612. CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration).
9. Al-Daghri N.M., Alkharfy K.M., Al-Othman A., El-Kholie E., Moharram O., Alokail M.S., et al. Vitamin D supplementation as an adjuvant therapy for patients with T2DM: an 18-month prospective interventional study. Cardiovasc Diabetol 2012, 11:85.
10. 3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: an open-label, blinded end point, randomized prospective trial (VitD-CHF trial). Am Heart J 2013, 166:357-364.
11. Bucolo G., David H. Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 1973, 19:476-482.
12. Allain C.C., Poon L.S., Chan C.S., Richmond W., Fu P.C. Enzymatic determination of total serum cholesterol. Clin Chem 1974, 20:470-475.
13. Burstein M., Morlin R. Precipitation of serum lipoproteins by anionic detergents in the presence of bivalent cations. Rev Eur Etud Clin Biol 1970, 15:109-113.
14. Wilson P.W., Abbott R.D., Garrison R.J., Castelli W.P. Estimation of very low density lipoprotein cholesterol from data on triglyceride concentration in serum. Clin Chem 1981, 27:2008-2010.
15. Friedewald W.T., Levy R.J., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma with polyanions. JLipid Res 1984, 11:583-594.
16. Ortega R.M., Requejo A.M., López-Sobaler A.M. Activity questionnaire. Nutriguía. Manual of clinical nutrition in primary care 2006, p 468. Complutense, Madrid. 1st ed. R.M. Requejo, R. Ortega (Eds.).
17. World Health Organization (WHO) Energy and protein requirements. Report of a joint FAO/WHO/UNU meeting 1985, WHO, Geneva, WHO Tech Rep Ser no 724.
18. Ortega R.M., Requejo A.M., Quintas E., Sánchez-Quiles B., López-Sobaler A.M., Andrés P. Estimated energy balance in female university students: differences with respect to body mass index and concern about body weight. Int J Obes 1996, 20:1127-1129.
19. Wang H., Xia N., Yang Y., Peng D.Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis 2012, 11:42.
20. Zittermann A., Frisch S., Berthold H.K., Götting C., Kuhn J., Kleesiek K., et al. Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers. Am J Clin Nutr 2009, 89:1321-1327.
21. Sanchez I., Mangoo-Karim R., Stubbs J.R., Yanev G.P., Wetmore J.B. Ethnic differences in 25-hydroxyvitamin D levels and response to treatment in CKD. Int Urol Nephrol 2013, 45:181-189.
22. Alvarez Jessica A., Bush Nikki C., Choquette Suzanne S., Hunter Gary R., Darnell Betty E., Oster Robert A., et al. Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women. Nutr Metab (Lond) 2010, 7:28.
23. Rostand S.G., Drüeke T.B. Parathyroid hormone, vitamin D, and cardiovascular disease in chronic renal failure. Kidney Int 1999, 56:383-392.
24. Steingrimsdottir L., Gunnarsson O., Indridason O.S., Franzson L., Sigurdsson G. Relationship between serum parathyroid hormone levels, vitamin D sufficiency, and calcium intake. JAMA 2005, 294:2336-2341.
25. Denke M.A., Fox M.M., Schulte M.C. Short-term dietary calcium fortification increases fecal saturated fat content and reduces serum lipids in men. JNutr 1993, 123:1047-1053.
26. Reid I.R. Effects of calcium supplementation on circulating lipids: potential pharmacoeconomic implications. Drugs Aging 2004, 21:7-17.
27. Vaskonen T. Dietary minerals and modification of cardiovascular risk factors. JNutr Biochem 2003, 14:492-506.
28. Grundy S.M., Denke M.A. Dietary influences on serum lipids and lipoproteins. JLipid Res 1990, 31:1149-1172.
29. Saunders D., Sillery J., Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988, 33:409-413.
30. Van der Meer R., Welberg J.W., Kuipers F., Kleibeuker J.H., Mulder N.H., Termont D.S., et al. Effects of supplemental dietary calcium on the intestinal association of calcium, phosphate, and bile acids. Gastroenterology 1990, 99:1653-1659.
31. Vaskonen T., Mervaala E., Sumuvuori V., Seppanen-Laakso T., Karppanen H. Effects of calcium and plant sterols on serum lipids in obese Zucker rats on a low-fat diet. Br J Nutr 2002, 87:239-245.
32. 2+ on the activation of microsomal triglyceride transfer protein in rat hepatocytes. Biol Pharm Bull 2005, 28:1418-1423.
33. Kane L., Moore K., Lütjohann D., Bikle D., Schwartz J.B. Vitamin D3 effects on lipids differ in statin and non-statin-treated humans: superiority of free 25-OH D levels in detecting relationships. JClin Endocrinol Metab 2013, 98:4400-4409.
34. Bolland M.J., Avenell A., Baron J.A., Grey A., MacLennan G.S., Gamble G.D., et al. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ. 2010, 341:c3691.
35. Witham M.D., Price R.J., Struthers A.D., Donnan P.T., Messow C.M., Ford I., et al. Cholecalciferol treatment to reduce blood pressure in older patients with isolated systolic hypertension. The VitDISH randomized controlled trial. JAMA Intern Med 2013, 173:1672-1679.