Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): A novel AT2R agonist effectively attenuates growth of PDAC grafts in mice

Cancer Biology and Therapy

Volumn 16, Issue 2, 2015, Pages 307-316

  Ishiguro, Susumu ^a   Yoshimura, Kiyoshi ^b   Tsunedomi, Ryouichi ^b   Oka, Masaaki ^b   Takao, Sonshin ^c   Inui, Makoto ^b   Kawabata, Atsushi ^a   Wall, Terrahn ^a   Magafa, Vassiliki ^d   Cordopatis, Paul ^d   Tzakos, Andreas G ^e   Tamura, Masaaki ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

^d UNIVERSITY OF PATRAS   (Greece)

^e UNIVERSITY OF IOANNINA   (Greece)

Author keywords

Angiotensin II type 2 receptor (AT2R); Apoptosis; Pancreatic ductal adenocarcinoma; Selective AT2R agonist

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN DERIVATIVE; ANTINEOPLASTIC AGENT; ANGIOTENSIN II;

ADULT; AGED; ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; GENETIC TRANSDUCTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; NONHUMAN; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION; GENETICS; ISOGRAFT; METABOLISM; MOUSE; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ANGIOTENSIN II; ANIMALS; APOPTOSIS; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; PANCREATIC NEOPLASMS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; SIGNAL TRANSDUCTION; TRANSPLANTATION, ISOGENEIC; TUMOR BURDEN; TUMOR STEM CELL ASSAY;

EID: 84924533040     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.1080/15384047.2014.1002357     Document Type: Article

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