Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

Human Molecular Genetics

Volumn 24, Issue 5, 2015, Pages 1478-1492

  Painter, Jodie N ^a   O'Mara, Tracy A ^a   Batra, Jyotsna ^b   Cheng, Timothy ^d   Lose, Felicity A ^a   Dennis, Joe ^e   Michailidou, Kyriaki ^e   Tyrer, Jonathan P ^f   Ahmed, Shahana ^f   Ferguson, Kaltin ^a   Healey, Catherine S ^f   Kaufmann, Susanne ^a   Hillman, Kristine M ^a   Walpole, Carina ^b   Moya, Leire ^b   Pollock, Pamela ^c   Jones, Angela ^d   Howarth, Kimberley ^d   Martin, Lynn ^d   Gorman, Maggie ^d   Hodgson, Shirley ^g   De Polanco, Ma Magdalena Echeverry ^h   Sans, Monica ⁱ   Carracedo, Angel ^j,k   Castellvi Bel, Sergi ^l   Rojas Martinez, Augusto ^m   Santos, Erika ⁿ   Teixeira, Manuel R ^o,p   Carvajal Carmona, Luis ^d,h,q   Shu, Xiao Ou ^r   Long, Jirong ^r   Zheng, Wei ^r   Xiang, Yong Bing ^s   Montgomery, Grant W ^a   Webb, Penelope M ^a   Scott, Rodney J ^t,u,v   McEvoy, Mark ^w   Attia, John ^t,w   Holliday, Elizabeth ^t,w   Martin, Nicholas G ^a   Nyholt, Dale R ^a   Henders, Anjali K ^a   Fasching, Peter A ^y,z   Hein, Alexander ^z   Beckmann, Matthias W ^z   Renner, Stefan P ^z   Dörk, Thilo ^aa   Hillemanns, Peter ^aa   Dürst, Matthias ^ab   Runnebaum, Ingo ^ab   Lambrechts, Diether ^ac,ad   Coenegrachts, Lieve ^ad   Schrauwen, Stefanie ^ad   Amant, Frederic ^ad   Winterhoff, Boris ^ae   Dowdy, Sean C ^ae   Goode, Ellen L ^ae   Teoman, Attila ^ae   Salvesen, Helga B ^af,ag   Trovik, Jone ^af,ag   Njolstad, Tormund S ^af,ag   Werner, Henrica M J ^af,ag   Ashton, Katie ^u,v   Proietto, Tony ^x   Otton, Geoffrey ^x   Tzortzatos, Gerasimos ^ah   Mints, Miriam ^ah   Tham, Emma ^ah   Hall, Per ^ah   Czene, Kamila ^ah   Liu, Jianjun ^ai   Li, Jingmei ^ai   Hopper, John L ^aj   Southey, Melissa C ^ak   Ekici, Arif B ^z   Ruebner, Matthias ^z   Johnson, Nicola ^al   Peto, Julian ^an   Burwinkel, Barbara ^ao,ap   Marme, Frederik ^ao   Brenner, Hermann ^ap   Dieffenbach, Aida K ^ap   Meindl, Alfons ^aq   Brauch, Hiltrud ^ar   Lindblom, Annika ^ah   Depreeuw, Jeroen ^ac   Moisse, Matthieu ^ac   Chang Claude, Jenny ^ap   Rudolph, Anja ^as   Couch, Fergus J ^ae   Olson, Janet E ^ae   Giles, Graham G ^aj,at,au   Bruinsma, Fiona ^at   Cunningham, Julie M ^ae   Fridley, Brooke L ^av   Børresen Dale, Anne Lise ^aw,ax   Kristensen, Vessela N ^aw,ax,ay   Cox, Angela ^az   Swerdlow, Anthony J ^am   Orr, Nicholas ^am   Bolla, Manjeet K ^e   Wang, Qin ^e   Weber, Rachel Palmieri ^ba   Chen, Zhihua ^bb   Shah, Mitul ^f   French, Juliet D ^a   Pharoah, Paul D P ^f   Dunning, Alison M ^f   Tomlinson, Ian ^d   Easton, Douglas F ^e,f   Edwards, Stacey L ^a   Thompson, Deborah J ^f   Spurdle, Amanda B ^a   more..

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b Translational Research Institute   (Australia)

^c QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e Department of Public Health and Primary Care ^*  (United Kingdom)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^h UNIVERSIDAD DEL TOLIMA   (Colombia)

ⁱ UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^j UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^k KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^l INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^m UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

ⁿ A C CAMARGO CANCER CENTER   (Brazil)

^o PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^p UNIVERSITY OF PORTO   (Portugal)

^q UNIVERSITY OF CALIFORNIA   (United States)

^r VANDERBILT INGRAM CANCER CENTER   (United States)

^s SHANGHAI CANCER INSTITUTE   (China)

^t HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

^u JOHN HUNTER HOSPITAL   (Australia)

^v Centre for Information Based Medicine School of Biomedical Science and Pharmacy   (United Kingdom)

^w Laboratory Medicine   (United States)

^x UNIVERSITY OF NEWCASTLE   (Australia)

^y UNIVERSITY OF CALIFORNIA   (United States)

^z UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^aa HANNOVER MEDICAL SCHOOL   (Germany)

^ab FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^ac DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^ad UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^ae MAYO CLINIC   (United States)

^af UNIVERSITY OF BERGEN   (Norway)

^ag HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^ah KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^ai GENOME INSTITUTE OF SINGAPORE   (Singapore)

^aj UNIVERSITY OF MELBOURNE   (Australia)

^ak UNIVERSITY OF MELBOURNE   (Australia)

^al Breakthrough Breast Cancer Research Centre   (United Kingdom)

^am INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^an LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^ao UNIVERSITY OF HEIDELBERG   (Germany)

^ap GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^aq TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^ar UNIVERSITY OF TÜBINGEN   (Germany)

^as UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^at CANCER EPIDEMIOLOGY CENTRE   (Australia)

^au MONASH UNIVERSITY   (Australia)

^av UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^aw OSLO UNIVERSITY HOSPITAL   (Norway)

^ax UNIVERSITY OF OSLO   (Norway)

^ay AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^az UNIVERSITY OF SHEFFIELD   (United Kingdom)

^ba DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bb H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; HEPATOCYTE NUCLEAR FACTOR 1BETA; HNF1B PROTEIN, HUMAN;

ALLELE; ARTICLE; CANCER PATIENT; CANCER RISK; CAUCASIAN; CHROMATIN STRUCTURE; CLINICAL LABORATORY; COMPUTER MODEL; CONTROLLED STUDY; DNA METHYLATION; ENDOMETRIUM CANCER; ENDOMETRIUM TUMOR; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HAPLOTYPE; HEPATOCYTE NUCLEAR FACTOR 1 HOMEOBOX B GENE; HUMAN; HUMAN CELL; HUMAN GENOME; INTRON; MAJOR CLINICAL STUDY; MULTIPLE CANCER; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS MAPPING; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE; BIOLOGY; CASE CONTROL STUDY; CHROMOSOMAL MAPPING; GENE LOCUS; GENETIC DATABASE; GENETIC EPIGENESIS; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; METABOLISM; RISK FACTOR; TUMOR CELL LINE;

ALLELES; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CHROMOSOME MAPPING; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; ENDOMETRIAL NEOPLASMS; EPIGENESIS, GENETIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC LOCI; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RISK FACTORS; RNA, MESSENGER;

EID: 84924440664     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu552     Document Type: Article

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