PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism

Journal of Immunology

Volumn 194, Issue 5, 2015, Pages 2289-2299

  McKay, Jerome T ^a   Egan, Ryan P ^a   Yammani, Rama D ^a   Chen, Lieping ^b   Shin, Tahiro ^c   Yagita, Hideo ^d   Haas, Karen M ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Texas Health Science Center at San Antonio   (United States)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; MEMBRANE PROTEIN; PNEUMOCOCCUS VACCINE; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN B7 DC; UNCLASSIFIED DRUG; BACTERIAL POLYSACCHARIDE; BACTERIUM ANTIBODY; CD274 PROTEIN, MOUSE; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 LIGAND 2; PROGRAMMED DEATH 1 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE RESISTANCE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN PRODUCTION; IN VIVO STUDY; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; STREPTOCOCCUS PNEUMONIAE; ANIMAL; B LYMPHOCYTE; BIOSYNTHESIS; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMORAL IMMUNITY; IMMUNOLOGY; KNOCKOUT MOUSE; MICROBIOLOGY; MORTALITY; PNEUMOCOCCAL INFECTIONS; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, CD274; B-LYMPHOCYTES; GENE EXPRESSION REGULATION; IMMUNITY, HUMORAL; IMMUNIZATION; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; POLYSACCHARIDES, BACTERIAL; PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN; PROGRAMMED CELL DEATH 1 RECEPTOR; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; SURVIVAL ANALYSIS;

EID: 84924386362     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401673     Document Type: Article

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