Selective hydrogenation of indolizines: An expeditious approach to derive tetrahydroindolizines and indolizidines from Morita-Baylis-Hillman adducts

Journal of Organic Chemistry

Volumn 80, Issue 5, 2015, Pages 2529-2538

  Teodoro, Bruno V M ^a   Correia, José Tiago M ^a   Coelho, Fernando ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

RATE CONSTANTS;

FUNCTIONALIZED; HIGH YIELD; INDOLIZIDINES; INDOLIZINES; LOW PRESSURES; MORITA-BAYLIS-HILLMAN ADDUCTS; SELECTIVE HYDROGENATION; STRAIGHTFORWARD STRATEGY;

HYDROGENATION;

1H,2H,3H CYCLOPENTA[B]INDOLIZIN 1 ONE; 2 [HYDROXY(PYRIDIN 2 YL)METHYL]CYCLOPENT 2 EN 1 ONE; 2 [HYDROXY(PYRIDIN 2 YL)METHYL]PROP 2 ENENITRILE; BUTYL 2 [HYDROXY(PYRIDIN 2 YL)METHYL]PROP 2 ENOATE; BUTYL 5,6,7,8 TETRAHYDROINDOLIZINE 2 CARBOXYLATE; BUTYL INDOLIZINE 2 CARBOXYLATE; ETHYL 2 [HYDROXY(PYRIDIN 2 YL)METHYL]PROP 2 ENOATE; ETHYL 5,6,7,8 TETRAHYDROINDOLIZINE 2 CARBOXYLATE; ETHYL INDOLIZINE 2 CARBOXYLATE; INDOLIZIDINE DERIVATIVE; INDOLIZINE 2 CARBONITRILE; INDOLIZINE DERIVATIVE; METHYL 2 [(6 BROMOPYRIDIN 2 YL)(HYDROXY)METHYL]PROP 2 ENOATE; METHYL 2 [HYDROXY(4 ETHYLPYRIDIN 2 YL)METHYL]PROP 2 ENOATE; METHYL 2 [HYDROXY(4 METHYLPYRIDIN 2 YL)METHYL]PROP 2 ENOATE; METHYL 2 [HYDROXY(5 METHYLPYRIDIN 2 YL)METHYL]PROP 2 ENOATE; METHYL 2 [HYDROXY(6 METHYLPYRIDIN 2 YL)METHYL]PROP 2 ENOATE; METHYL 2 [HYDROXY(PYRIDIN 2 YL)METHYL]PROP 2 ENOATE; METHYL 2 [HYDROXY(QUINOLIN 2 YL)METHYL]PROP 2 ENOATE; METHYL 5 BROMOINDOLIZINE 2 CARBOXYLATE; METHYL 5 METHYLINDOLIZINE 2 CARBOXYLATE; METHYL 5,6,7,8 TETRAHYDROINDOLIZINE 2 CARBOXYLATE; METHYL 6 METHYLINDOLIZINE 2 CARBOXYLATE; METHYL 7 ETHYLINDOLIZINE 2 CARBOXYLATE; METHYL 7 METHYLINDOLIZINE 2 CARBOXYLATE; METHYL INDOLIZINE 2 CARBOXYLATE; METHYL PYRROLO[1,2 A]QUINOLINE 2 CARBOXYLATE; TERT BUTYL 2 [HYDROXY(PYRIDIN 2 YL)METHYL]PROP 2 ENOATE; TERT BUTYL INDOLIZINE 2 CARBOXYLATE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DIASTEREOISOMER; DRUG SYNTHESIS; HYDROGENATION; MORITA BAYLIS HILLMAN ADDUCTS; ROOM TEMPERATURE; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; HYDROGENATION; INDOLIZIDINES; INDOLIZINES; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 84924311343     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo502471q     Document Type: Article

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