In vivo anticancer activity of rhomboidal Pt(II) metallacycles

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 52, 2014, Pages 18448-18453

  Grishagin, Ivan V ^a   Pollock, J Bryant ^b   Kushal, Swati ^a   Cook, Timothy R ^b,c   Stang, Peter J ^b   Olenyuk, Bogdan Z ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cell culture; Fluorescence; Supramolecular coordination complexes; Tumor growth; Xenografts

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; PLATINUM COMPLEX; RHODAMINE 6G; RHOMBOIDAL PLATINUM(II) COMPLEX; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ORGANOMETALLIC COMPOUND; PLATINUM;

ADENOCARCINOMA IN SITU; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; BRIGHT FIELD MICROSCOPY; CANCER INHIBITION; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; ENERGY ABSORPTION; FEMALE; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTUM YIELD; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; UTERINE CERVIX CARCINOMA; ANIMAL; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; METABOLISM; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; HELA CELLS; HUMANS; MICE; NEOPLASMS, EXPERIMENTAL; ORGANOMETALLIC COMPOUNDS; PLATINUM; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84924299920     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1418712111     Document Type: Article

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