Anti-proliferative effects of polyphenols from pomegranate rind (Punica granatum L.) on EJ bladder cancer cells via regulation of p53/miR-34a Axis

Phytotherapy Research

Volumn 29, Issue 3, 2015, Pages 415-422

  Zhou, Benhong ^a   Yi, Huilan ^a   Tan, Jun ^b   Wu, Yue ^a   Liu, Gang ^a   Qiu, Zhenpeng ^c  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

anti proliferative effects; miR 34a; p53; pomegranate rind

Indexed keywords

CASPASE 3; ELLAGIC ACID; HERMES ANTIGEN; MESSENGER RNA; MICRORNA 34A; MYC PROTEIN; PLACEBO; POLYPHENOL DERIVATIVE; POMEGRANATE EXTRACT; PROTEIN BCL 2; PROTEIN C JUN; PROTEIN P53; PUNICALAGIN A; PUNICALAGIN B; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MICRORNA; MIRN34 MICRORNA, HUMAN; POLYPHENOL; SMALL INTERFERING RNA; TP53 PROTEIN, HUMAN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER; BLADDER CANCER CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IC50; MOUSE MODEL; NONHUMAN; PHYTOCHEMISTRY; POMEGRANATE; PROTEIN EXPRESSION; PROTEIN RNA BINDING; PROTEIN TARGETING; QUANTITATIVE STUDY; RAT; REAL TIME POLYMERASE CHAIN REACTION; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; ANIMAL; BLADDER TUMOR; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; EPITHELIUM CELL; FRUIT; GENE EXPRESSION REGULATION; GENETICS; LYTHRACEAE; MALE; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

LYTHRACEAE; PUNICA GRANATUM;

ANIMALS; ANTIGENS, CD44; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; EPITHELIAL CELLS; FRUIT; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MALE; MICE, NUDE; MICRORNAS; POLYPHENOLS; PROTO-ONCOGENE PROTEINS C-MYC; PUNICACEAE; RATS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER NEOPLASMS;

EID: 84924298273     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5267     Document Type: Article

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