Astragaloside IV prevents lipopolysaccharide-induced injury in H9C2 cardiomyocytes

Chinese Journal of Natural Medicines

Volumn 13, Issue 2, 2015, Pages 127-132

  Wang, Shi Guang ^a,b   Xu, Yan ^b   Xie, Hao ^c   Wang, Wei ^d   Chen, Xiao Hu ^e  

^a ANHUI UNIVERSITY OF CHINESE MEDICINE   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

^d HEFEI NORMAL UNIVERSITY   (China)

^e THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Astragaloside IV; H9C2 Cardiomyocytes; Lipopolysaccharide

Indexed keywords

ASTRAGALOSIDE IV; CREATINE KINASE; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MALONALDEHYDE; MESSENGER RNA; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; ASTRAGALOSIDE A; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SAPONIN; TRITERPENE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE CELL; HEART PROTECTION; LIPID PEROXIDATION; MTT ASSAY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; APOPTOSIS; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; RAT;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; DRUGS, CHINESE HERBAL; LIPOPOLYSACCHARIDES; MYOCYTES, CARDIAC; NF-KAPPA B; RATS; SAPONINS; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84924295540     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(15)60016-4     Document Type: Article

References (30)

1. Chirico G, Loda C Laboratory aid to the diagnosis and therapy of infection in the neonate [J]. Pediatr Rep 2011, 3(1):e1.
2. Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care [J]. Crit Care Med 2001, 29(7):1303-1310.
3. Hotchkiss RS, Karl IE The pathophysiology and treatment of sepsis [J]. N Engl J Med 2003, 348(2):138-150.
4. Beuchée A, Carrault G, Bansard JY, et al. Uncorrelated randomness of the heart rate is associated with sepsis in sick premature infants [J]. Neonatology 2009, 96(2):109-114.
5. Ramana KV, Willis MS, White MD, et al. Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition [J]. Circulation 2006, 114(17):1838-1846.
6. Chen X, Peng LH, Li N, et al. The healing and anti-scar effects of astragaloside IV on the wound repair in vitro and in vivo [J]. J Ethnopharmacol 2012, 139(3):721-727.
7. Ren S, Zhang H, Mu Y, et al. Pharmacological effects of Astragaloside IV: a literature review [J]. J Tradit Chin Med 2013, 33(3):413-416.
8. Tohda C, Tamura T, Matsuyama S, et al. Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus [J]. Br J Pharmacol 2006, 149(5):532-541.
9. Zhang Y, Zhu H, Huang C, et al. Astragaloside IV exerts antiviral effects against coxsackievirus B3 by upregulating interferon-gamma [J]. J Cardiovasc Pharmacol 2006, 47(2):190-195.
10. Cao Q, Kaur C, Wu CY, et al. Nuclear factor-kappa β regulates Notch signaling in production of proinflammatory cytokines and nitric oxide in murine BV-2 microglial cells [J]. Neuroscience 2011, 192:140-154.
11. He ZQ, Findlay JA Constituents of Astragalus membranaceus [J]. J Nat Prod 1991, 54(3):810-815.
12. Li W, Fitzloff JF Determination of astragaloside IV in Radix astragali (Astragalus membranaceus var. monghulicus) using high-performance liquid chromatography with evaporative light-scattering detection [J]. J Chromatogr Sci 2001, 39(11):459-462.
13. Hu JY, Han J, Chu ZG, et al. Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels [J]. Clin Exp Pharmacol Physiol 2009, 36(4):351-357.
14. Li ZP, Cao Q Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats [J]. Acta Pharmacol Sin 2002, 23(10):898-904.
15. Li L, Tao HY, Chen JB Anti-apoptosis effect of astragaloside on adriamycin induced rat's cardiotoxicity [J]. Chin J Integr Med 2006, 26(11):1011-1014.
16. John E, Pais P, Furtado N, et al. Early effects of lipopolysaccharide on cytokine release, hemodynamic and renal function in newborn piglets [J]. Neonatology 2007, 93(2):106-112.
17. Milstein JM, Milano E, Goetzman BW, et al. Role of nitric oxide in cardiovascular responses to endotoxemia in neonatal lambs [J]. Neonatology 1999, 75(3):187-198.
18. Fink MP, Heard SO Laboratory models of sepsis and septic shock [J]. J Surg Res 1990, 49(2):186-196.
19. Comstock KL, Krown KA, Page MT, et al. LPS-induced TNF-α release from and apoptosis in rat cardiomyocytes: Obligatory role for CD14 in mediating the LPS response [J]. J Mol Cell Cardiol 1998, 30(12):2761-2775.
20. Koch L, Fritzsching B, Frommhold D, et al. Lipopolysaccharide-induced expression of Th1/Th2 cytokines in whole neonatal cord and adult blood: role of nuclear factor-kappa B and p38 MAPK [J]. Neonatology 2010, 99(2):140-145.
21. Cain BS, Meldrum DR, Dinarello CA, et al. Tumor necrosis factor-alpha and interleukin-1 beta synergistically depress human myocardial function[J]. Crit Care Med 1999, 27(7):1309-1318.
22. Kumar A, Thota V, Dee L, et al. Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum [J]. J Exp Med 1996, 183(3):949-958.
23. Finkel T, Holbrook NJ Oxidants, oxidative stress and the biology of ageing [J]. Nature 2000, 408(6809):239-247.
24. Takano H, Zou Y, Hasegawa H, et al. Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases [J]. Anioxid Redox Sign 2003, 5(6):789-794.
25. Lim KH, Ko D, Kim JH Cardioprotective potential of Korean Red Ginseng extract on isoproterenol-induced cardiac injury in rats [J]. J Gins Res 2013, 37(3):273.
26. Batra S, Kumar R, Kapoor AK, et al. Alterations in antioxidant status during neonatal sepsis [J]. Ann Trop Paediatr 2000, 20(1):27-33.
27. Demirbilek S, Ersoy MÖ, Demirbilek S, et al. Effects of polyenylphosphatidylcholine on cytokines, nitrite/nitrate levels, antioxidant activity and lipid peroxidation in rats with sepsis [J]. Intensive Care Med 2004, 30(10):1974-1978.
28. Abraham E NF-[kappa] B activation [J]. Crit Care Med 2000, 28(4):N100-N104.
29. Baldwin AS Series introduction: the transcription factor NF-κB and human disease [J]. J Clin Invest 2001, 107(1):3-6.
30. Rogler G, Brand K, Vogl D, et al. Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa [J]. Gastroenterology 1998, 115(2):357-369.