The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB

Retrovirology

Volumn 12, Issue 1, 2015, Pages

  Liu, Zhenlong ^a,e   Pan, Qinghua ^a   Liang, Zhibin ^a,b   Qiao, Wentao ^b   Cen, Shan ^c   Liang, Chen ^a,d  

^a MCGILL UNIVERSITY   (Canada)

^b NANKAI UNIVERSITY   (China)

^c INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

CypA; HIV; MxB; Transmitted founder virus

Indexed keywords

ANTIVIRUS AGENT; CYCLOPHILIN A; MYXOVIRUS RESISTANCE PROTEIN B; UNCLASSIFIED DRUG; GAG PROTEIN; MUTANT PROTEIN; MX2 PROTEIN, HUMAN; MYXOVIRUS RESISTANCE PROTEIN; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG SENSITIVITY; FOUNDER EFFECT; GENETIC DATABASE; GENETIC TRANSFECTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOID CELL LINE; MOLECULAR INTERACTION; NONHUMAN; PHENOTYPIC VARIATION; PM1 CELL LINE; PROTEIN DEPLETION; PROTEIN EXPRESSION; SUPT1 CELL LINE; VIRUS CAPSID; VIRUS MUTATION; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS STRAIN; GENETIC SELECTION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNE EVASION; IMMUNOLOGY; METABOLISM; MISSENSE MUTATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE; ORTHOMYXOVIRIDAE;

CYCLOPHILIN A; HIV CORE PROTEIN P24; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE EVASION; MUTANT PROTEINS; MUTATION, MISSENSE; MYXOVIRUS RESISTANCE PROTEINS; PROTEIN BINDING; SELECTION, GENETIC;

EID: 84924266757     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/s12977-014-0129-1     Document Type: Article

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