Engineering of a hybrid polymer-lipid nanocarrier for the nasal delivery of tenofovir disoproxil fumarate: Physicochemical, molecular, microstructural, and stability evaluation

European Journal of Pharmaceutical Sciences

Volumn 71, Issue , 2015, Pages 99-111

  Pokharkar, Varsha B ^a   Jolly, Mallika R ^a   Kumbhar, Dipak D ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

Amorphous; Crystallization behavior; H bonding; Hybrid nanocarrier; Shear thinning; Tenofovir disoproxil fumarate

Indexed keywords

LAURIC ACID; POLYACRYLIC ACID; TENOFOVIR DISOPROXIL; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DRUG CARRIER; LIPID; NANOPARTICLE; POLYMER; RNA DIRECTED DNA POLYMERASE INHIBITOR; TENOFOVIR;

ANIMAL TISSUE; ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; EMULSION; EX VIVO STUDY; FACTORIAL DESIGN; HISTOPATHOLOGY; HYDROGEN BOND; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR INTERACTION; MOLECULAR PROBE; NANOENCAPSULATION; NONHUMAN; NOSE MUCOSA; PARTICLE SIZE; PHYSICAL CHEMISTRY; POWDER; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SURFACE PROPERTY; THERMAL ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; ANATOMY AND HISTOLOGY; CHEMISTRY; DRUG EFFECTS; FLOW KINETICS; INTRANASAL DRUG ADMINISTRATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POWDER DIFFRACTION; SCANNING ELECTRON MICROSCOPY;

ADMINISTRATION, INTRANASAL; ANTI-HIV AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; DRUG LIBERATION; DRUG STABILITY; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NASAL MUCOSA; POLYMERS; POWDER DIFFRACTION; REVERSE TRANSCRIPTASE INHIBITORS; RHEOLOGY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TENOFOVIR; X-RAY DIFFRACTION;

EID: 84924250260     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.02.009     Document Type: Article

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