Toll-like receptor activation in basophils contributes to the development of IgG4-related disease

Journal of Gastroenterology

Volumn 48, Issue 2, 2013, Pages 247-253

  Watanabe, Tomohiro ^a   Yamashita, Kouhei ^a   Sakurai, Toshiharu ^b   Kudo, Masatoshi ^b   Shiokawa, Masahiro ^a   Uza, Norimitsu ^a   Kodama, Yuzo ^a   Uchida, Kazushige ^c   Okazaki, Kazuichi ^c   Chiba, Tsutomu ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Kindai University   (Japan)

^c KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Basophil; IgG4 related disease; TLR

Indexed keywords

B CELL ACTIVATING FACTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G4; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 8; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; THYMIC STROMAL LYMPHOPOIETIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; IMMUNOGLOBULIN G; LIGAND; TNFSF13B PROTEIN, HUMAN;

ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNE PANCREATITIS; B LYMPHOCYTE; BASOPHIL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOGLOBULIN G4 RELATED DISEASE; IMMUNOGLOBULIN PRODUCTION; INNATE IMMUNITY; MEDIATOR RELEASE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; AUTOIMMUNE DISEASE; BIOSYNTHESIS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION;

AUTOIMMUNE DISEASES; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTES; BASOPHILS; HUMANS; IMMUNITY, INNATE; IMMUNOGLOBULIN G; INTERLEUKIN-13; LIGANDS; LYMPHOCYTE ACTIVATION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

MLCS; MLOWN;

EID: 84878393728     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-012-0626-8     Document Type: Article

References (16)

1. Okazaki K, Kawa S, Kamisawa T, et al. Japanese clinical guidelines for autoimmune pancreatitis. Pancreas. 2009;38: 849-66.
2. Masaki Y, Dong L, Kurose N, et al. Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis. 2009;68: 1310-5.
3. Ravi K, Chari ST, Vege SS, et al. Inflammatory bowel disease in the setting of autoimmune pancreatitis. Inflamm Bowel Dis. 2009;15: 1326-30.
4. Strober W, Murray PJ, Kitani A, et al. Signalling pathways and molecular interactions of NOD1 and NOD2. Nat Rev Immunol. 2006;6: 9-20.
5. Watanabe T, Yamashita K, Fujikawa S, et al. Activation of Tolllike receptors and NOD-like receptors is involved in enhanced IgG4 responses in autoimmune pancreatitis. Arthritis Rheum. 2012;64: 914-24.
6. Jeannin P, Lecoanet S, Delneste Y, et al. IgE versus IgG4 production can be differentially regulated by IL-10. J Immunol. 1998;160: 3555-61.
7. Sokol CL, Medzhitov R. Role of basophils in the initiation of Th2 responses. Curr Opin Immunol. 2010;22: 73-7.
8. Paul WE, Zhu J. How are T(H)2-type immune responses initiated and amplified? Nat Rev Immunol. 2010;10: 225-35.
9. Chen K, Xu W, Wilson M, et al. Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. Nat Immunol. 2009;10: 889-98.
10. Phillips C, Coward WR, Pritchard DI, et al. Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mites. J Leukoc Biol. 2003;73: 165-71.
11. Bieneman AP, Chichester KL, Chen YH, et al. Toll-like receptor 2 ligands activate human basophils for both IgE-dependent and IgE-independent secretion. J Allergy Clin Immunol. 2005;115: 295-301.
12. Yamanishi H, Kumagi T, Yokota T, et al. Clinical significance of B cell-activating factor in autoimmune pancreatitis. Pancreas. 2011;40: 840-5.
13. Siracusa MC, Saenz SA, Hill DA, et al. TSLP promotes interleukin- 3-independent basophil haematopoiesis and type 2 inflammation. Nature. 2011;477: 229-33.
14. Watanabe T, Katsukura H, Shirai Y, et al. Helper CD4? T cells for IgE response to a dietary antigen develop in the liver. J Allergy Clin Immunol. 2003;111: 1375-85.
15. Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest. 2007;117: 514-21.
16. Sah RP, Chari ST, Pannala R, et al. Differences in clinical profile and relapse rate of type 1 versus type 2 autoimmune pancreatitis. Gastroenterology 2010;139:140-8 (quiz e12-3).