Developing neuroimaging phenotypes of the default mode network in PTSD: Integrating the resting state, working memory, and structural connectivity

Journal of Visualized Experiments

Volumn , Issue 89, 2014, Pages

  Philip, Noah S ^a   Carpenter, S Louisa ^a   Sweet, Lawrence H ^b  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Default mode network; Diffusion tensor imaging; Functional connectivity; Functional magnetic resonance imaging; Issue 89; Medicine; Neuroimaging; Posttraumatic stress disorder; Structural connectivity

Indexed keywords

EID: 84924165032     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/51651     Document Type: Article

References (46)

1. Raichle, M. E. et al. A default mode of brain function. Proc Natl Acad Sci U S A. 98, 676-682, (2001).
2. Fransson, P. How default is the default mode of brain function? Further evidence from intrinsic BOLD signal fluctuations. Neuropsychologia. 44, 2836-2845, doi:10.1016/j.neuropsychologia.2006.06.017, (2006).
3. Fransson, P., & Marrelec, G. The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis. Neuroimage. 42, 1178-1184, doi:10.1016/j.neuroimage.2008.05.059, (2008).
4. Conrad, C. D. et al. Chronic glucocorticoids increase hippocampal vulnerability to neurotoxicity under conditions that produce CA3 dendritic retraction but fail to impair spatial recognition memory. J Neurosci. 27, 8278-8285, doi:10.1523/JNEUROSCI.2121-07.2007, (2007).
5. Patel, R. et al. Disruptive effects of glucocorticoids on glutathione peroxidase biochemistry in hippocampal cultures. J Neurochem. 82, 118-125, doi:10.1046/j.1471-4159.2002.00948.x, (2002).
6. Bluhm, R. L. et al. Alterations in default network connectivity in posttraumatic stress disorder related to early-life trauma. J Psychiatry Neurosci. 34, 187-194, (2009).
7. Lanius, R. A. et al. Default mode network connectivity as a predictor of post-traumatic stress disorder symptom severity in acutely traumatized subjects. Acta Psychiatr Scand. 121, 33-40, doi:10.1111/j.1600-0447.2009.01391.x, (2010).
8. Sripada, R. K. et al. Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks. Psychosom Med. 74, 904-911, doi:10.1097/PSY.0b013e318273bf33, (2012).
9. Greicius, M. D. et al. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A. 100, 253-258, doi:10.1073/pnas.0135058100, (2003).
10. Fox, M. D., & Greicius, M. Clinical applications of resting state functional connectivity. Front Syst Neurosci. 4, 19, doi:10.3389/fnsys.2010.00019, (2010).
11. Sweet, L. H. et al. Effects of nicotine withdrawal on verbal working memory and associated brain response. Psychiatry Res. 183, 69-74, doi:10.1016/j.pscychresns.2010.04.014, (2010).
12. Samuelson, K. W. et al. Neuropsychological functioning in posttraumatic stress disorder and alcohol abuse. Neuropsychology. 20, 716-726, doi:10.1037/0894-4105.20.6.716, (2006).
13. Vasterling, J. J. et al. Attention and memory dysfunction in posttraumatic stress disorder. Neuropsychology. 12, 125-133, doi:10.1037//0894-4105.12.1.125, (1998).
14. Yehuda, R. et al. Learning and memory in combat veterans with posttraumatic stress disorder. Am J Psychiatry. 152, 137-139, (1995).
15. Moores, K. A. et al. Abnormal recruitment of working memory updating networks during maintenance of trauma-neutral information in post-traumatic stress disorder. Psychiatry Res. 163, 156-170, doi:10.1016/j.pscychresns.2007.08.011, (2008).
16. Rougemont-Bucking, A. et al. Altered processing of contextual information during fear extinction in PTSD: an fMRI study. CNS Neurosci Ther. 17, 227-236, doi:10.1111/j.1755-5949.2010.00152.x, (2011).
17. Peres, J. F. et al. Police officers under attack: resilience implications of an fMRI study. J Psychiatr Res. 45, 727-734, doi:10.1016/j.jpsychires.2010.11.004, (2011).
18. Philip, N. S. et al. Early life stress is associated with greater default network deactivation during working memory in healthy controls: a preliminary report. Brain Imaging Behav. 7, 204-212, doi:10.1007/s11682-012-9216-x, (2013).
19. Sweet, L. H. et al. Imaging phonological similarity effects on verbal working memory. Neuropsychologia. 46, 1114-1123, doi:10.1016/j.neuropsychologia.2007.10.022, (2008).
20. Abe, O. et al. Voxel-based diffusion tensor analysis reveals aberrant anterior cingulum integrity in posttraumatic stress disorder due to terrorism. Psychiatry Res. 146, 231-242, doi:10.1016/j.pscychresns.2006.01.004, (2006).
21. Kim, S. J. et al. Asymmetrically altered integrity of cingulum bundle in posttraumatic stress disorder. Neuropsychobiology. 54, 120-125, doi:10.1159/000098262, (2006).
22. Vogt, B. A. et al. Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regions. Cereb Cortex. 2, 435-443, doi:10.1093/cercor/2.6.435-a, (1992).
23. Philip, N. S. et al. Decreased default network connectivity is associated with early life stress in medication-free healthy adults. Eur Neuropsychopharmacol. 23, 24-32, doi:10.1016/j.euroneuro.2012.10.008, (2013).
24. First, M. B., Spitzer, R.L., Gibbon, M., Williams, J.B.W. Structured Clinical Interview for Axis I DSM-IV Disorders. (1994).
25. Blake, D. D. et al. The development of a clinician-administered PTSD scale. J Trauma Stress. 8, 75-90, doi:10.1007/BF02105408, (1995).
26. Folstein, M. F. et al. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 12, 189-198, (1975).
27. Wolfe, J. W., Kimerling, R., Brown, P.J., Chrestman, K.R., & Levin, K. Psychometric review of The Life Stressor Checklist-Revised. Sidran Press, (1996).
28. Bernstein, D. P., & Fink, L. Childhood trauma questionnaire: a retrospective self-report. Pearson Education, Inc., (1998).
29. Cohen, S. et al. A global measure of perceived stress. J Health Soc Behav. 24, 385-396, doi:10.2307/2136404, (1983).
30. Rush, A. J. et al. The 16-item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): A psychometric evaluation in patients with chronic major depression. Biol Psychiatry. 54, 573-583, doi:10.1016/S0006-3223(02)01866-8, (2003).
31. Reynolds, R. AFNI program: afni_proc.py., http://afni.nimh.nih.gov/pub/dist/doc/program_help/afni_proc.py.html, (2006).
32. Posner, J. et al. Antidepressants normalize the default mode network in patients with dysthymia. JAMA Psychiatry. 70, 373-382, doi:10.1001/jamapsychiatry.2013.455, (2013).
33. Murphy, K. et al. The impact of global signal regression on resting state correlations: are anti-correlated networks introduced? Neuroimage. 44, 893-905, doi:10.1016/j.neuroimage.2008.09.036, (2009).
34. Saad, Z. S. et al. Trouble at rest: how correlation patterns and group differences become distorted after global signal regression. Brain Connect. 2, 25-32, (2012).
35. Shirer, W. R. et al. Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cereb Cortex. 22, 158-165, doi:10.1089/brain.2012.0080, (2012).
36. Fisher, R. A. Frequency distribution of the values of the correlation coefficient in samples of an indefinitely large population. Biometrika. 10, 507-521, (1915).
37. Cox, R. W. AFNI program: 3dClustSim., http://afni.nimh.nih.gov/pub/dist/doc/program_help/3dClustSim.html, (2010).
38. Smith, S. M. et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage. 31, 1487-1505, (2006).
39. Mori, S., Wakana, S., Nagae-Poetscher, L.M., & van Zijl, P.C.M. MRI Atlas of Human White Matter. Elsevier (2005).
40. Catani, M., & Thiebaut de Schotten, M. A diffusion tensor imaging tractography atlas for virtual in vivo dissections. Cortex. 44, 1105-1132, doi:10.1016/j.cortex.2008.05.004, (2008).
41. Sweet, L. H. et al. Default network response to a working memory challenge after withdrawal of continuous positive airway pressure treatment for obstructive sleep apnea. Brain Imaging Behav. 4, 155-163, doi:10.1007/s11682-010-9095-y, (2010).
42. Cole, D. M. et al. Advances and pitfalls in the analysis and interpretation of resting-state FMRI data. Front Syst Neurosci. 4, 8, doi:10.3389/fnsys.2010.00008, (2012).
43. Power, J. D. et al. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage. 59, 2142-2154, doi:10.1016/j.neuroimage.2011.10.018, (2012).
44. Satterthwaite, T. D. et al. Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth. Neuroimage. 60, 623-632, doi:10.1016/j.neuroimage.2011.12.063, (2012).
45. Van Dijk, K. R. et al. The influence of head motion on intrinsic functional connectivity MRI. Neuroimage. 59, 431-438, doi:10.1016/j.neuroimage.2011.07.044, (2012).
46. Philip, N. S. et al. Regional homogeneity and resting state functional connectivity: associations with exposure to early life stress. Psychiatry Res. 214, 247-53, doi:10.1016/j.pscychresns.2013.07.013, (2013).