Cutaneous PEComa: A rare entity to consider in an unusual site

American Journal of Dermatopathology

Volumn 36, Issue 12, 2014, Pages e198-e201

  Ieremia, Eleni ^a   Robson, Alistair ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

clear cell; cutaneous; neoplasm; PEComa

Indexed keywords

MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOCLONAL ANTIBODY HMB 45;

ADULT; ARTICLE; CASE REPORT; CHROMATIN; COLLAGEN FIBER; CUTANEOUS PERIVASCULAR EPITHELIOID CELL TUMOR; GIANT CELL; HISTIOCYTOMA; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PERIVASCULAR EPITHELIOID CELL TUMOR; PRIORITY JOURNAL; SKIN DISEASE; CHEMISTRY; PATHOLOGY; SKIN TUMOR;

ADULT; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PERIVASCULAR EPITHELIOID CELL NEOPLASMS; SKIN NEOPLASMS;

EID: 84924086579     PISSN: 01931091     EISSN: 15330311     Source Type: Journal    
DOI: 10.1097/DAD.0000000000000041     Document Type: Article

References (20)

1. Bonetti F, Pea M, Martignoni G, et al. Clear cell ('sugar') tumour of the lung is a lesion strictly related to angiomyolipoma-the concept of a family of lesions characterised by the presence of the perivascular epithelioid cells (PEC). Pathology. 1994;26:230
2. Zamboni G, Pea M, Martignon G, et al. Clear cell sugar tumour of the pancreas. A novel member of the family of lesions characterised by the presence of perivascular epithelioid cells. Am J Surg Pathol. 1996;20:722
3. de Saint Aubain Somerhausen N, Galdon MG, Bouffioux B, et al. Clear cell 'sugar' tumour (PEComa) of the skin: a case report. J Cutan Pathol. 2005;32:441-444
4. Bandhlish A, Leon Barnes E, Rabban JT, et al. Perivascular epithelioid cell tumors (PEComas) of the head and neck: report of three cases and review of the literature. Head Neck Pathol. 2011;5:233-240
5. Martignoni G, Pea M, Reghellin D, et al. PEComas: the past, the present and the future. Virchows Arch. 2008;452:119-132
6. Ghazali N, Cascarini L, Norris P, et al. Perivascular epithelioid cell tumour (PEComa) of the cheek. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:e26-e31
7. Chaplin A, Corand DM, Tatlidil C, et al. Primary cutaneous PEComa. Am J Dermatopathol. 2010;32:310-312
8. Fisher C. Unusual myoid, perivascular and postradiation lesions, with emphasis on atypical vascular lesion, postradiation cutaneous angiosarcoma, myoepithelial tumours, myopericytoma and perivascular epithelioid cell tumour. Semin Diagn Pathol. 2013;30:73-84
9. Tan J, Peach AH, Merchant W. PEComas of the skin: more common in the lower limb?. Two case reports. Histopathology. 2007;51:135-136
10. Walsh SN, Sangueza OP. PEComas: a review with emphasis on cutaneous lesions. Semin Diagn Pathol. 2009;26:123-130
11. Beer TW. Cutaneous angiomyolipomas are HMB45 negative, not associated with tuberous sclerosis and should be considered as angioleiomyomas with fat. Am J Dermatopathol. 2005;27:418-421
12. Mikoshiba Y, Murat H, Ashida A, et al. Case of cutaneous angiomyolipoma in the ear. J Dermatol. 2012;39:808-809
13. Liegl B, Hornick JL, Fletcher CD. Primary cutaneous PEComa: distinctive clear cell lesions of skin. Am J Surg Pathol. 2008;32:608-614
14. Mentzel T, Reisshauer S, Rutten A, et al. Cutaneous clear cell myomelanocytic tumour: a new member of the growing family of perivascular epithelioid cell tumours (PEComas). Clinicopathological and immunohistochemical analysis of seven cases. Histopathology. 2005;46:498-504
15. Pusiol T, Morichetti D, Zorzi MG, et al. HMB-45 negative clear cell perivascular epithelioid cell tumour of the skin. Acta Dermatovenerol Croat. 2012;20:27-29
16. Folpe AL, Mentzel T, Lehr HA, et al. Perivascular epithelioid cell neoplasm soft tissue and gynaecologic origin: a clinicpathologic study of 26 cases and review of literature. Am J Surg Pathol. 2005;29:1558-1575
17. Llamas-Velasco M, Mentzel T, Requena L, et al. Cutaneous PEComa does not harbour TFE3 gene fusions: immunohistochemical and molecular study of 17 cases. Histopathology. 2013;63:122-129
18. Hantschke M, Mentzel T, Rutten A, et al. Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical and molecular analysis of 12 cases emphasizing its distinction from dermal melanoma. Am J Surg Pathol. 2010;34:216-222
19. Calder KB, Schlauder S, Morgan MB. Malignant perivascular epithelioid tumor (PEComa): a case report and literature review of cutaneous/subcutaneous presentations. J Cutan Pathol. 2008;35:499-503
20. Harris GC, McCulloch T, Perks G, et al. Malignant perivascular epithelioid cell tumour (PEComa) of soft tissue. A unique case. Am J Surg Pathol. 2004;28:1655-1658