Malignant perivascular epithelioid cell tumor ('PEComa'): A case report and literature review of cutaneous/subcutaneous presentations

Journal of Cutaneous Pathology

Volumn 35, Issue 5, 2008, Pages 499-503

  Calder, Kenneth B ^a   Schlauder, Scott ^a   Morgan, Michael B ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CALPONIN; CANCER ANTIBODY; CD45 ANTIGEN; CELL MARKER; DESMIN; FLUORESCENT DYE; HMB 45 ANTIGEN; MELAN A; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PROTEIN NKIC3; PROTEIN S 100; UNCLASSIFIED DRUG;

AGED; ARTICLE; CASE REPORT; CERVICAL LYMPH NODE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE COURSE; EPITHELIOID CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MALE; PATHOLOGICAL ANATOMY; PERIVASCULAR EPITHELIOID CELL TUMOR; SCALP TUMOR; SKIN CANCER;

AGED; DIAGNOSIS, DIFFERENTIAL; EPITHELIOID CELLS; HUMANS; LYMPH NODES; MALE; MELANOMA; NEOPLASMS, CONNECTIVE AND SOFT TISSUE; SCALP; SKIN NEOPLASMS; SMOOTH MUSCLE TUMOR; TUMOR MARKERS, BIOLOGICAL;

EID: 42049087247     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2007.00842.x     Document Type: Article

References (33)

1. Mentzel T, Reißhauer S, Rütten A, et al. Cutaneous clear cell myomelanocytic tumor: a new member of the growing family of perivascular epithelioid cell tumours (PEComas). Clinicopathological and immunohistochemical analysis of seven cases. Histopathology 2005 46 : 498.
2. Bonetti F, Pea M, Martignoni G, et al. PEC and sugar. Am J Surg Pathol 1992 16 : 307.
3. Pea M, Bonetti F, Zamboni G, et al. Clear cell tumor and angiomyolipoma. Am J Surg Pathol 1991 15 : 199.
4. Pea M, Bonetti F, Zamboni G, et al. Melanocyte-marker HMB-45 is regularly expressed in angiomyolipoma of the kidney. Pathology 1991 23 : 185.
5. Weeks DA, Malott RL, Arnesen M, et al. Hepatic angiomyolipoma with striated granules and positivity with melanoma-specific antibody (HMB-45): a report of two cases. Ultrastruct Pathol 1991 15 : 563.
6. Gaffey MJ, Mills SE, Zarbo RJ, et al. Clear cell tumor of the lung. Immunohistochemical and ultrastructural evidence of melanogenesis. Am J Surg Pathol 1991 15 : 644.
7. Gal AA, Koss MN, Hochholzer L, et al. An immunohistochemical study of benign clear cell ('sugar') tumor of the lung. Arch Pathol Lab Med 1991 115 : 1034.
8. Bonetti F, Pea M, Martignoni G, et al. Cellular heterogeneity in lymphangiomyomatosis of the lung. Hum Pathol 1991 22 : 727.
9. Folpe AL, Mentzel T, Lehr H, et al. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin. Am J Surg Pathol. 2005 29 : 1558.
10. de Saint Aubain Somerhausen N, Gomez Galdon M, Bouffioux B, et al. Clear cell 'sugar' tumor (PEComa) of the skin: a case report. J Cutan Pathol 2005 32 : 441.
11. Tazelaar HD, Batts KP, Srigley JR. Primary extrapulmonary sugar tumor (PEST): a report of four cases. Mod Pathol 2001 14 : 615.
12. Liebow AA, Castleman B. Benign clear cell ('sugar') tumors of the lung. Am J Pathol 1963 43 : 13.
13. Zamboni G, Pea M, Martignoni G, et al. Clear cell 'sugar' tumor of the pancreas. A novel member of the family of lesions characterized by the presence of perivascular epithelioid cells. Am J Surg Pathol 1996 20 : 722.
14. Pan CC, Yang AH, Chiang H. Malignant perivascular epithelioid cell tumor involving the prostate. Arch Pathol Lab Med 2003 127 : E96.
15. Vang R, Kempson RL. Perivascular cell tumor ('PEComa') of the uterus: a subset of HMB-45 positive epithelioid mesenchymal neoplasms with an uncertain relationship to pure smooth muscle tumors. Am J Surg Pathol 2002 26 : 1.
16. Pan CC, Yu IT, Yang AH, Chiang H. Clear cell myomelanocytic tumor of the urinary bladder. Am J Surg Pathol 2003 27 : 689.
17. Bonetti F, Martignoni G, Colato C, et al. Abdominopelvic sarcoma of perivascular epithelioid cells. Report of four cases in young women, one with tuberous sclerosis. Mod Pathol 2001 14 : 563.
18. Insabato L, De Rosa G, Terraciano LM, et al. Primary monotypic epithelioid angiomyolipoma of bone. Histopathology 2002 40 : 286.
19. Folpe AL, McKenney JK, Li Z, et al. Clear cell myomelanocytic tumor of the thigh: report of a unique case. Am J Surg Pathol 2002 26 : 809.
20. Crowson AN, Taylor JR, Magro CM. Cutaneous clear cell myomelanocytic tumor-perivascular epithelioid cell tumor: first reported case. Mod Pathol 2003 16 : 400.
21. Harris GC, McCulloch TA, Perks G, et al. Malignant perivascular epithelioid cell tumour ('PEComa') of soft tissue: a unique case. Am J Surg Pathol 2004 28 : 1655.
22. Folpe AL. Neoplasms with perivascular epithelioid differentiation (PEComas). In Fletcher CDM, Unni KK, Mertens F, eds. WHO classification of tumours. Tumours of soft tissue and bone. Lyon, IARS Press : 221 222.
23. Carlson JA, Dickersin GR, Sober AJ, Barnhill RL. Desmoplastic neurotropic melanoma. A clinicopathologic analysis of 28 cases. Cancer 1995 75 : 478.
24. Riccioni L, Di Tommaso L, Collina G. Actin-rich desmoplastic malignant melanoma: report of three cases. Am J Dermatopathol 1999 21 : 537.
25. Hornick JL, Fletches CD. Myoepithelial tumors of soft tissue: a clinicopathologic and immunohistochemical study of 101 cases with evaluation of prognostic parameters. Am J Surg Pathol 2003 9 : 1183.
26. Hayhurst C, Mcmurtrie A, Brydon HL. Cutaneous meningioma of the scalp. Acta Neurochir (Wien) 2004 146 : 1383.
27. Mederos LJ, Michie SA, Johnson DE, et al. An immunoperoxidase study of renal cell carcinomas: correlation with nuclear grade, cell type, and histologic pattern. Hum Pathol 1988 19 : 980.
28. Kim MK, Kim S. Immunohistochemical profile of common epithelial neoplasms arising in the kidney. Appl Immunohistochem Mol Morphol 2002 10 : 332.
29. Gaffey MJ, Traweek S, Mills SE, et al. Cytokeratin expression in adrenocortical neoplasia: an immunohistochemical and biochemical study with implications for differential diagnosis of adrenocortical, hepatocellular, and renal cell carcinoma. Hum Pathol 1992 23 : 144.
30. Lin F, Yang W, Betten M, et al. Expression of S-100 protein in renal cell neoplasms. Hum Pathol 2006 37 : 462.
31. Zimmer LA, Gillman G, Barnes L. Postauricular epithelioid sarcoma. Otolaryngol Head Neck Surg 2004 131 : 1022.
32. Zeppa P, Errico ME, Palombini L. Epithelioid sarcoma: report of two cases diagnosed by fine-needle aspiration biopsy with immunocytochemical correlation. Diagn Cytopathol 1999 21 : 405.
33. Fisher C. Epithelioid sarcoma: the spectrum of ultrastructural differentiation in seven immunohistochemically defined cases. Hum Pathol 1988 19 : 265.