Malignant perivascular epithelioid cell tumour ("PEComa") of soft tissue: A unique case

American Journal of Surgical Pathology

Volumn 28, Issue 12, 2004, Pages 1655-1658

  Harris, Gavin C ^a   McCulloch, Thomas A ^b   Perks, Graeme ^b   Fisher, Cyril ^c  

^a CANTERBURY HEALTH LABORATORIES   (New Zealand)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^c ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

Clear cell myomelanocytic tumor; Malignant; Perivascular epithelioid cell; Soft tissue

Indexed keywords

ANTINEOPLASTIC AGENT;

AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; EPITHELIUM TUMOR; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INGUINAL REGION; LUNG METASTASIS; MALE; PERIVASCULAR EPITHELIOID CELL TUMOR; POSTOPERATIVE CARE; SOFT TISSUE CANCER; THORAX RADIOGRAPHY; TRANSPLANTATION; ULTRASTRUCTURE; VASCULAR DISEASE;

AGED; CARCINOMA; EPITHELIOID CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; SOFT TISSUE NEOPLASMS;

EID: 9444228250     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200412000-00017     Document Type: Article

References (19)

1. Bonetti F, Pea M, Martignoni G, et al. PEC and sugar. Am J Surg Pathol. 1992;16:307-308.
2. Bonetti F, Pea M, Martignoni G, et al. The perivascular epithelioid cell and related lesions. Adv Anat Pathol. 1997;4:343-358.
3. Carsillo T, Astrinidis A, Henske EP. Mutations in the tuberose sclerosis complex gene TSC2 are cause of sporadic pulmonary lymphangiomyomatosis. Proc Natl Acad Sci USA. 2000;23:6085-6090.
4. Chan J, Tsang W, Pau M, et al. Lymphangiomyomatosis and angiomyolipoma: closely related entities characterised by hamartomatous proliferation of HMB-45-positive smooth muscle. Histopathology. 1993;22:445-455.
5. Diment J, Colecchia M. Myomelanocytic tumour of the thigh [letter]. Am J Surg Pathol. 2003;27:1288.
6. El-Hashemite N, Zhang H, Henske EP, et al. Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma. Lancet. 2003;361:1348-1349.
7. Folpe AL, Goodman ZD, Ishak KG, et al. Clear cell myomelanocytic tumour of the falciform ligament/ligamentum teres: a novel member of the perivascular epithelioid clear cell family of tumours with a predilection for children and young adults. Am J Surg Pathol. 2000;24:1239-1246.
8. Folpe A, McKenney J, Zhiming L, et al. Clear cell myomelanocytic tumour of the thigh. Am J Surg Pathol. 2002;26:809-812.
9. Govender D, Sabaratnam R, Essa A. Clear cell 'sugar' tumour of the breast: another extrapulmonary site and review of the literature. Am J Surg Pathol. 2002;26:670-675.
10. Henske EP, Wessner LL, Golden J, et al. Loss of tuberin in both subependymal astrocytoma and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumours. Am J Pathol. 1997;151:1639-1647.
11. Johnson SR, Clelland CA, Ronan J, et al. The TSC2 product tuberin is expressed in lymphangiomyomatosis and angiomyolipoma. Histopathology. 2002;40:458-463.
12. Karbowniczek M, Yu J, Henske EP. Renal angiomyolipomas from patients with sporadic lymphangiomyomatosis contain both neoplastic and non-neoplastic vascular structures. Am J Pathol. 2003;162:491-500.
13. Pan C, Yang A, Chiang H. Malignant perivascular epithelioid cell tumour involving the prostate. Arch Pathol Lab Med. 2003;127:e96-e98.
14. Pan C, Yu I, Yang A, et al. Clear cell myomelanocytic tumour of the urinary bladder. Am J Surg Pathol. 2003;27:689-692.
15. Plank TL, Logginidou H, Klei-Szanto A, et al. The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas. Mod Pathol. 1999;12:539-545.
16. Ruco L, Pilozzi E, Wedard B, et al. Epithelioid lymphangioleiomyomatosis- like tumour of the uterus in a patient without tuberous sclerosis: a lesion mimicking epithelioid leiomyosarcoma. Histopathology. 1998;33:87-94.
17. Tazelaar H, Batts K, Srigley J. Primary extrapulmonary sugar tumour (PEST): a report of four cases. Mod Pathol. 2001;14:615-622.
18. Vang R, Kempson R. Perivascular epithelioid cell tumour ('PEComa') of the uterus. Am J Surg Pathol. 2002;26:1-13.
19. Yanai H, Matsuura H, Sonobe H, et al. Perivascular epithelioid tumour of the jejunum. Pathol Res Pract. 2003;199:47-50.