The effect of reverse remodeling on long-term survival in mildly symptomatic patients with heart failure receiving cardiac resynchronization therapy: Results of the REVERSE study

Heart Rhythm

Volumn 12, Issue 3, 2015, Pages 524-530

  Gold, Michael R ^a   Daubert, Claude ^b   Abraham, William T ^c   Ghio, Stefano ^d   St John Sutton, Martin ^e   Hudnall, John Harrison ^f   Cerkvenik, Jeffrey ^f   Linde, Cecilia ^g  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RENNES UNIVERSITY HOSPITAL   (France)

^c OHIO STATE UNIVERSITY   (United States)

^d FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^e HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^f MEDTRONIC INC   (United States)

^g KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cardiac resynchronizationtherapy; Defibrillator; Heartfailure; Implantable cardioverter defibrillator; Remodeling

Indexed keywords

ADULT; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; FOLLOW UP; HEART DEATH; HEART FAILURE; HEART LEFT BUNDLE BRANCH BLOCK; HEART LEFT VENTRICLE EJECTION FRACTION; HEART VENTRICLE REMODELING; HUMAN; ISCHEMIC HEART DISEASE; LEFT VENTRICULAR END SYSTOLIC VOLUME INDEX; LONG TERM SURVIVAL; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC DYSFUNCTION; AGED; CLINICAL TRIAL; DIAGNOSTIC IMAGING; DOUBLE BLIND PROCEDURE; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; MORTALITY; MULTICENTER STUDY; PATHOPHYSIOLOGY; PROCEDURES; STATISTICS AND NUMERICAL DATA; SURVIVOR; TREATMENT OUTCOME;

AGED; CARDIAC RESYNCHRONIZATION THERAPY; DOUBLE-BLIND METHOD; ECHOCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; STROKE VOLUME; SURVIVORS; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84924070990     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2014.11.014     Document Type: Article

References (38)

1. S. Cazeau, C. Leclercq, T. Lavergne, S. Walker, C. Varma, C. Linde, S. Garrigue, L. Kappenberger, G.A. Haywood, M. Santini, C. Bailleul, and J.C. Daubert Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay N Engl J Med 344 2001 873 880
2. W.T. Abraham, W.G. Fisher, A.L. Smith MIRACLE Study Group Multicenter InSync Randomized Clinical Evaluation. Cardiac resynchronization in chronic heart failure N Engl J Med 346 2002 1845 1853
3. C. Linde, C. Leclercq, and S. Rex Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in cardiomyopathy (MUSTIC) study J Am Coll Cardiol 40 2002 111 118
4. S.L. Higgins, J.D. Hummel, I.K. Niazi, M.C. Giudici, S.J. Worley, L.A. Saxon, J.P. Boehmer, M.B. Higginbotham, T. De Marco, E. Foster, and P.G. Yong Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias J Am Coll Cardiol 42 2003 1454 1459
5. J.B. Young, W.T. Abraham, A.L. Smith, A.R. Leon, R. Lieberman, B. Wilkoff, R.C. Canby, J.S. Schroeder, L.B. Liem, S. Hall, and K. Wheelan Multicenter InSync ICD Randomized Clinical Evaluation (MIRACLE ICD) Trial Investigators. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial JAMA 289 2003 2685 2694
6. M.R. Bristow, L.A. Saxon, J. Boehmer, S. Krueger, D.A. Kass, T. De Marco, P. Carson, L. DiCarlo, D. DeMets, B.G. White, D.W. DeVries, and A.M. Feldman Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure N Engl J Med 350 2004 2140 2150
7. J.G. Cleland, J.C. Daubert, E. Erdmann, N. Freemantle, D. Gras, L. Kappenberger, and L. Tavazzi Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators. The effect of cardiac resynchronization on morbidity and mortality in heart failure N Engl J Med 352 2005 1539 1549
8. J.G. Cleland, J.C. Daubert, E. Erdmann, N. Freemantle, D. Gras, L. Kappenberger, and L. Tavazzi Longer-term effects of cardiac resynchronization therapy on mortality in heart failure [the CArdiac REsynchronization-Heart Failure (CARE-HF) trial extension phase] Eur Heart J 27 2006 1928 1932
9. C. Linde, W.T. Abraham, M.R. Gold St, M. John Sutton, S. Ghio, and C. Daubert REVERSE (REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction) Study Group. Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients with left ventricular dysfunction and previous heart failure symptoms J Am Coll Cardiol 52 2008 1834 1843
10. A.J. Moss, W.J. Hall, and D.S. Cannom Cardiac-resynchronization therapy for the prevention of heart-failure events N Engl J Med 361 2009 1329 1338
11. A.S. Tang, G.A. Wells, and M. Talajic Cardiac-resynchronization therapy for mild-to-moderate heart failure N Engl J Med 363 2010 2385 2395
12. M.A. Konstam, M.W. Kronenberg, M.F. Rousseau, J.E. Udelson, J. Melin, D. Stewart, N. Dolan, T.R. Edens, S. Ahn, and D. Kinen Effects of the angiotensin converting enzyme inhibitor, enalapril, on the long-term progression of left ventricular dilatation in patients with asymptomatic systolic dysfunction Circulation 88 1993 2277 2283
13. M.A. Konstam, R.D. Patten, and I. Thomas Effects of losartan and captopril on left ventricular volumes in elderly patients with heart failure: results of the ELITE ventricular function substudy Am Heart J 139 2000 1081 1087
14. B. Pitt, P.A. Poole-Wilson, R. Segal, F.A. Martinez, K. Dickstein, A.J. Camm, M.A. Konstam, G. Riegger, G.H. Klinger, J. Neaton, D. Sharma, and B. Thiyagarajan Randomised trial of losartan versus captopril on mortality in patients with symptomatic heart failure: the Losartan Heart Failure Survival Study ELITE II Lancet 355 2000 1582 1587
15. M.R. Bristow, E.M. Gilbert, W.T. Abraham, K.F. Adams, M.B. Fowler, R.E. Hershberger, S.H. Kubo, K.A. Narahara, H. Ingersoll, S. Krueger, S. Young, and N. Shusterman MOCHA Investigators. Carvedilol produces dose related improvements in left ventricular function and survival in subjects with chronic heart failure Circulation 94 1996 2807 2816
16. W.S. Colucci, T.J. Kolias, K.F. Adams, W.F. Armstrong, J.K. Ghali, S.S. Gottlieb, B. Greenberg, M.I. Klibaner, M.L. Kukin, J.E. Sugg REVERT Study Group Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the REversal of VEntricular Remodeling with Toprol-XL (REVERT) trial Circulation 116 2007 49 56
17. J.C. Tardif, E.O. O'Meara, M. Komajda, M. Böhm, J.S. Borer, I. Ford, L. Tavazzi, and K. Swedberg SHIFT Investigators. Effects of selective heart rate reduction with ivabradine on left ventricular remodeling and function: results from the SHIFT echocardiography substudy Eur Heart J 32 2011 2507 2515
18. D.G. Kramer, T.A. Trikalinos, D.M. Kent, G.V. Antonopoulos, M.A. Konstam, and J.E. Udelson Quantitative evaluation of drug and device effects on ventricular remodeling as predictors of therapeutic effects on mortality in patients with heart failure and reduced ejection fraction J Am Coll Cardiol 56 2010 392 406
19. M.R. Gold, C. Linde, W.T. Abraham, A. Gardiwal, and J.C. Daubert The impact of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in mild heart failure Heart Rhythm 8 2011 679 684
20. A. Barsheshet, P.J. Wang, A.J. Moss, S.D. Solomon, A. Al-Ahmad, S. McNitt, E. Foster, D.T. Huang, H.U. Klein, W. Zareba, M. Eldar, and I. Goldenberg Reverse remodeling and the risk of ventricular tachyarrhythmias in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy) J Am Coll Cardiol 57 2011 2416 2423
21. C. Linde, M. Gold, W.T. Abraham, J.C. Daubert for the REVERSE Study Group Rationale and design of a randomized controlled trial to assess the safety and efficacy of cardiac resynchronization therapy in patients with asymptomatic left ventricular dysfunction with previous symptoms or mild heart failure - the REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) study Am Heart J 151 2006 288 294
22. J.C. Daubert, M.R. Gold, W.T. Abraham, S. Ghio, C. Hassager, G. Goode, T. Szili-Török, C. Linde REVERSE Study Group Prevention of disease progression by cardiac resynchronization therapy in patients with asymptomatic or mildly symptomatic left ventricular dysfunction: insights from the European cohort of the REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) trial J Am Coll Cardiol 54 2009 1837 1846
23. G. Gregoratos, J. Abrams, A.E. Epstein, R.A. Freedman, D.L. Hayes, M.A. Hlatky, R.E. Kerber, G.V. Naccarelli, M.H. Schoenfeld, M.J. Silka, and S.L. Winters ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pacemakers and antiarrhythmia devices: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines) J Am Coll Cardiol 40 2002 1703 1719
24. S.G. Priori, E. Aliot, and C. Blomstrom-Lundqvist Update of the guidelines on sudden cardiac death of the European Society of Cardiology Eur Heart J 24 2003 13 15
25. M. Packer Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure J Card Fail 7 2001 176 182
26. R.M. Lang, M. Bierig, and R.B. Devereux Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology J Am Soc Echocardiogr 18 2005 1440 1463
27. C. Linde, M.R. Gold, W.T. Abraham St, M. John Sutton, S. Ghio, J. Cerkvenik, C. Daubert REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction Study Group Long-term impact of cardiac resynchronization therapy in mild heart failure: five year results from the REsynchronization reverses Remodeling in Systolic left vEntricular dysfunction (REVERSE) study Eur Heart J 34 2013 2592 2599
28. A.E. Epstein, J.P. DiMarco, and K.A. Ellenbogen 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society J Am Coll Cardiol 61 2013 e6 e75
29. The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure N Engl J Med 325 1991 293 302
30. M.F. Rousseau, M.A. Konstam, C.R. Benedict, J. Donckier, L. Galanti, J. Melin, D. Kinan, S. Ahn, J.M. Ketelslegers, and H. Pouleur Progression of left ventricular dysfunction secondary to coronary artery disease, sustained neurohormonal activation and effects of ibopamine therapy during long-term therapy with angiotensin-converting enzyme inhibitor Am J Cardiol 73 1994 488 493
31. C.M. Linde, M. Gold, W.T. Abraham, J.C. Daubert on behalf of the REVERSE Study Group Baseline characteristics of patients randomised in REsynchronization reverses Remodeling in Systolic left vEntricular dysfunction (REVERSE) study Congest Heart Fail 14 2008 66 74
32. C. Ypenburg, R.J. van Bommel, C.J. Borleffs, G.B. Bleeker, E. Boersma, M.J. Schalij, and J.J. Bax Long-term prognosis after cardiac resynchronization therapy is related to the extent of left ventricular reverse remodeling at midterm follow-up J Am Coll Cardiol 53 2009 483 490
33. C.M. Yu, G.B. Bleeker, J.W. Fung, M.J. Schalij, Q. Zhang, E.E. van der Wall, Y.S. Chan, S.L. Kong, and J.J. Bax Left ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy Circulation 112 2005 1580 1586
34. S.D. Solomon, E. Foster, M. Bourgoun, A. Shah, E. Viloria, M.W. Brown, W.J. Hall, M.A. Pfeffer, and A.J. Moss MADIT-CRT Investigators. Effect of cardiac resynchronization therapy on reverse remodeling and relation to outcome: Multicenter Automatic Defibrillator Implantation Trial: Cardiac Resynchronization Therapy Circulation 122 2010 985 992
35. M.S.J. Sutton, S. Ghio, T. Plappert, L. Tavazzi, L. Scelsi, C. Daubert, W.T. Abraham, M.R. Gold, C. Hassager, J.M. Herre, and C. Linde REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) Study Group. Cardiac resynchronization induces major structural and functional reverse remodeling in patients with New York Heart Association class I/II heart failure Circulation 120 2009 1858 1865
36. I. Goldenberg, A.J. Moss, and W. Hall Predictors of response to cardiac resynchronization therapy in the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT) Circulation 124 2011 1527 1536
37. M.R. Gold, C. Thebault, C. Linde, W.T. Abraham, B. Gerritse, S. Ghio St, M. John Sutton, and J.C. Daubert Effect of QRS duration and morphology on cardiac resynchronization therapy outcomes in mild heart failure: results from the Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) study Circulation 126 2012 822 829
38. M.R. Gold, J.C. Daubert, W.T. Abraham, C. Hassager, J.L. Dinerman, J.H. Hudnall, J. Cerkvenik, and C. Linde Implantable defibrillators improve survival in patients with mildly symptomatic heart failure receiving cardiac resynchronization therapy: analysis of the long-term follow-up of Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) Circ Arrhythm Electrophysiol 6 2013 1163 1168