Effect of basic and acidic additives on the separation of some basic drug enantiomers on polysaccharide-based chiral columns with acetonitrile as mobile phase

Chirality

Volumn 27, Issue 3, 2015, Pages 228-234

  Gogaladze, Khatuna ^a   Chankvetadze, Lali ^a   Tsintsadze, Maia ^b   Farkas, Tivadar ^c   Chankvetadze, Bezhan ^a  

^a TBILISI STATE UNIVERSITY   (Georgia)

^b GEORGIAN TECHNICAL UNIVERSITY   (Georgia)

^c Phenomenex   (United States)

Author keywords

Basic chiral drugs; Effect of minor additives; Enantiomer elution order; Polysaccharide based chiral selectors; Separation of enantiomers

Indexed keywords

ACEBUTOLOL; ACETONITRILE; ALPRENOLOL; AMYLOSE; ATENOLOL; BETAXOLOL; BISOPROLOL; BUNITROLOL; BUPRANOLOL; CARBAMIC ACID DERIVATIVE; CELIPROLOL; CELLULOSE; DRUG ADDITIVE; FORMIC ACID; ISOPRENALINE; MABUTEROL; METIPRANOLOL; METOPROLOL; NIFENALOL; OXPRENOLOL; PHENYLCARBAMIC ACID DERIVATIVE; POLYSACCHARIDE; SOTALOL; TOLIPROLOL; UNCLASSIFIED DRUG; ACETONITRILE DERIVATIVE;

ARTICLE; CHIRALITY; CONTROLLED STUDY; ELUTION; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR RECOGNITION; PHASE SEPARATION; PRIORITY JOURNAL; CHEMISTRY; PROCEDURES; STEREOISOMERISM;

ACETONITRILES; AMYLOSE; CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; STEREOISOMERISM;

EID: 84924061954     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.22417     Document Type: Article

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