On the effect of basic and acidic additives on the separation of the enantiomers of some basic drugs with polysaccharide-based chiral selectors and polar organic mobile phases

Journal of Chromatography A

Volumn 1317, Issue , 2013, Pages 167-174

  Mosiashvili, L ^a   Chankvetadze, L ^a   Farkas, T ^b   Chankvetadze, B ^a  

^a TBILISI STATE UNIVERSITY   (Georgia)

^b PHENOMENEX INC   (United States)

Author keywords

Basic chiral drugs; Chiral HPLC; Enantioseparations; Polysaccharide based chiral stationary phases; The role of minor additives

Indexed keywords

CHIRAL DRUGS; CHIRAL HPLC; CHIRAL RECOGNITION MECHANISMS; ENANTIOSEPARATIONS; POLAR ORGANIC MOBILE PHASIS; POLYSACCHARIDE-BASED CHIRAL STATIONARY PHASIS; SEPARATION OF ENANTIOMERS; SEPARATION SELECTIVITY;

ENANTIOMERS; SEPARATION;

ADDITIVES;

2 PROPANOL; ACETONITRILE; ACID; BASE; CARAZOLOL; CARVEDILOL; CELLULOSE; DIETHYLAMINE; FORMIC ACID; ORGANIC COMPOUND; PINDOLOL; POLYSACCHARIDE; PROPRANOLOL; TRAMADOL; TRIFLUOROACETIC ACID; ACETIC ACID DERIVATIVE; ACETONITRILE DERIVATIVE; AMYLOSE; DRUG;

ANALYTICAL PARAMETERS; ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG STRUCTURE; ENANTIOSEPARATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; CHEMISTRY; DEVICES; ISOLATION AND PURIFICATION; PH; STEREOISOMERISM;

ACETATES; ACETONITRILES; AMYLOSE; CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; PHARMACEUTICAL PREPARATIONS; STEREOISOMERISM;

EID: 84887159777     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.08.029     Document Type: Article

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