Optimization of the liquid chromatography enantioseparation of chiral acidic compounds using cellulose tris(3-chloro-4-methylphenylcarbamate) as chiral selector and polar organic mobile phases

Journal of Chromatography A

Volumn 1234, Issue , 2012, Pages 56-63

  Dossou, K S S ^a   Farcas, E ^a   Servais, A C ^a   Chiap, P ^b   Chankvetadze, B ^c   Crommen, J ^a   Fillet, M ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c TBILISI STATE UNIVERSITY   (Georgia)

Author keywords

Chiral acidic compounds; Chlorinated cellulose based chiral stationary phases; Enantioseparation; Liquid chromatography; Optimization; Polar organic mobile phases

Indexed keywords

ACIDIC ADDITIVES; ACIDIC COMPOUNDS; BUTYLAMINES; CENTRAL COMPOSITE; CHIRAL SELECTOR; CHIRAL STATIONARY PHASIS; CHLORINATED CELLULOSE BASED CHIRAL STATIONARY PHASES; CONCENTRATION OF ACETIC ACID; DIETHYLAMINES; ENANTIORESOLUTION; ENANTIOSEPARATIONS; MOBILE PHASE; MODEL COMPOUND; NEUTRAL COMPOUNDS; ORGANIC MOBILE PHASIS; RAPID DEVELOPMENT; STATIONARY PHASE; TRIETHYLAMINES; TRIFLUOROACETIC ACIDS; ZWITTERIONIC DRUGS;

ACETIC ACID; ACETONITRILE; ADDITIVES; CELLULOSE; CHLORINE; DIAGNOSIS; DRUG PRODUCTS; FORMIC ACID; LEAD COMPOUNDS; LIQUID CHROMATOGRAPHY; OPTIMIZATION; ORGANIC SOLVENTS; PH;

CHLORINE COMPOUNDS;

2 PHENOXYPROPIONIC ACID; ACETIC ACID; ACETONITRILE; ACID; BUTYLAMINE; CARPROFEN; CELLULOSE DERIVATIVE; CELLULOSE TRIS(3 CHLORO 4 METHYLPHENYLCARBAMATE); CHLORTALIDONE; CLORAZEPATE; DIETHYLAMINE; FENOPROFEN; FLURBIPROFEN; FORMIC ACID; HEXOBARBITAL; HYDRATROPIC ACID; IBUPROFEN; INDOPROFEN; KETOPROFEN; KETOROLAC; LORAZEPAM; LORMETAZEPAM; OFLOXACIN; PROGLUMIDE; PROPIONIC ACID DERIVATIVE; TEMAZEPAM; TRIETHYLAMINE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; WARFARIN;

ARTICLE; CHEMICAL ANALYSIS; CHIRALITY; CONCENTRATION (PARAMETERS); ENANTIOSEPARATION; LIQUID CHROMATOGRAPHY; PHASE SEPARATION; POLAR ORGANIC MOBILE PHASE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE;

ACETATES; ACETONITRILES; AMINES; CELLULOSE; CHROMATOGRAPHY, LIQUID; HYDROGEN-ION CONCENTRATION; MULTIVARIATE ANALYSIS; PHARMACEUTICAL PREPARATIONS; PHENYLCARBAMATES; STEREOISOMERISM;

EID: 84858799352     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.01.072     Document Type: Article

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