Metabolic process engineering of Clostridium tyrobutyricum Δack-adhE2 for enhanced n-butanol production from glucose: Effects of methyl viologen on NADH availability, flux distribution, and fermentation kinetics

Biotechnology and Bioengineering

Volumn 112, Issue 4, 2015, Pages 705-715

  Du, Yinming ^a   Jiang, Wenyan ^a   Yu, Mingrui ^b   Tang, I Ching ^b   Yang, Shang Tian ^a  

^a The Ohio State University   (United States)

^b Bioprocessing Innovative Company   (United States)

Author keywords

Artificial electron carrier; Clostridium tyrobutyricum; Metabolic flux analysis; Methyl viologen; N butanol

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CLOSTRIDIUM; ELECTRONS; GLUCOSE; METABOLISM; VOLATILE FATTY ACIDS;

CLOSTRIDIUM TYROBUTYRICUM; ELECTRON CARRIER; METABOLIC FLUX ANALYSIS; METHYL VIOLOGEN; N-BUTANOL;

FERMENTATION;

ACETIC ACID; ALCOHOL; BUTANOL; BUTYRIC ACID; FERREDOXIN; GLUCOSE; HYDROGEN; PARAQUAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; ACETIC ACID DERIVATIVE; BUTYRIC ACID DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE;

ARTICLE; BIOSYNTHESIS; CLOSTRIDIUM TYROBUTYRICUM; CONTROLLED STUDY; FED BATCH FERMENTATION; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; NONHUMAN; PH; BIOTECHNOLOGY; ENZYMOLOGY; FERMENTATION; GENE EXPRESSION; GENETICS; METABOLISM; PROCEDURES;

CLOSTRIDIUM TYROBUTYRICUM;

1-BUTANOL; ACETATES; BIOTECHNOLOGY; BUTYRATES; CLOSTRIDIUM TYROBUTYRICUM; FERMENTATION; GENE EXPRESSION; GLUCOSE; HYDROGEN; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS; NAD; OXIDOREDUCTASES; PARAQUAT;

EID: 84924042410     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25489     Document Type: Article

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