Unravelling adverse reactions to NSAIDs using systems biology

Trends in Pharmacological Sciences

Volumn 36, Issue 3, 2015, Pages 172-180

  Perkins, James R ^a   Sanak, Marek ^b   Canto, Gabriela ^c   Blanca, Miguel ^a   Cornejo García, José Antonio ^a,b  

^a HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c HOSPITAL UNIVERSITARIO INFANTA LEONOR   (Spain)

Author keywords

adverse drug reactions; functional genomics; high throughput data.; hypersensitivity drug reaction; nonsteroidal anti inflammatory drugs (NSAIDs); NSAIDs hypersensitivity; systems biology

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT;

ADVERSE DRUG REACTION; ANTINEOPLASTIC ACTIVITY; ASTHMA; CANCER GROWTH; DRUG HYPERSENSITIVITY; DRUG MECHANISM; DRUG METABOLISM; EPIGENETICS; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HYPERSENSITIVITY; LIPIDOMICS; NONHUMAN; NSAID EXACERBATED RESPIRATORY DISEASE; NSAID INDUCED URTICARIA ANGIOEDEMA; POLLEN ALLERGY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMS BIOLOGY; GENETICS; METABOLISM;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG HYPERSENSITIVITY; HUMANS; PROTEIN INTERACTION MAPS; SYSTEMS BIOLOGY;

EID: 84923933595     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2014.12.003     Document Type: Review

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