Zingerone silences quorum sensing and attenuates virulence of Pseudomonas aeruginosa

Fitoterapia

Volumn 102, Issue , 2015, Pages 84-95

  Kumar, Lokender ^a   Chhibber, Sanjay ^a   Kumar, Rajnish ^b   Kumar, Manoj ^b   Harjai, Kusum ^a  

^a PANJAB UNIVERSITY   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Antibiotic resistance; Biofilm formation; Phytochemical; Quorum sensing; Virulence; Zingerone

Indexed keywords

ELASTASE; HEMOLYSIN; PLANT MEDICINAL PRODUCT; PROTEINASE; PYOCYANINE; RHAMNOLIPID; VANILLIN; VIRULENCE FACTOR; ZINGERONE; ANTIINFECTIVE AGENT; GUAIACOL;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOFILM; CHEMICAL STRUCTURE; COMPUTER MODEL; EXTRACTION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUANTITATIVE ASSAY; QUORUM SENSING; TWITCHING MOTILITY; ANALOGS AND DERIVATIVES; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; PATHOGENICITY; VIRULENCE;

PSEUDOMONAS AERUGINOSA;

ANTI-BACTERIAL AGENTS; BIOFILMS; GUAIACOL; MICROBIAL SENSITIVITY TESTS; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; VIRULENCE;

EID: 84923928617     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2015.02.002     Document Type: Article

References (47)

1. H. Zhu, R. Bandara, T.C.R. Conibear, S.J. Thuruthyil, S.A. Rice, and S. Kjelleberg Pseudomonas aeruginosa with LasI quorum-sensing deficiency during corneal infection Invest Ophthalmol Vis Sci 45 2004 1897 1903
2. E.A.M. Tron, H.L. Wilke, S.R. Petermann, and L. Rust Pseudomonas aeruginosa from canine otitis externa exhibit a quorum sensing deficiency Vet Microbiol 99 2004 121 129
3. J.S. Friedstat, M.E. Moore, J.M. Weber, S.P. Fagan, and J. Goverman Selection of appropriate empiric gram-negative coverage in a multinational pediatric burn hospital J Burn Care Res 34 2013 203 210
4. I.A.S.V. Packiavathy, S. Priya, S.K. Pandian, and A.V. Ravi Inhibition of biofilm development of uropathogens by curcumin - an anti-quorum sensing agent from Curcuma longa Food Chem 148 2014 453 460
5. D.J. Smith, I.L. Lamont, G.J. Anderson, and D.W. Reid Targeting iron uptake to control Pseudomonas aeruginosa infections in cystic fibrosis Eur Respir J 42 2013 1723 1736
6. M.R. Filbin, S.A. Arias, C.A. Camargo Jr., A. Barche, and D.J. Pallin Sepsis visits and antibiotic utilization in U.S. emergency departments Crit Care Med 42 2014 528 535
7. I. Thaipisuttikul, L.E. Hittle, R. Chandra, D. Zangari, C.L. Dixon, and T.A. Garrett A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A Mol Microbiol 91 2014 158 174
8. G. Bonfiglio, Y. Laksai, L. Franchino, G. Amicosante, and G. Nicoletti Mechanisms of β-lactam resistance amongst Pseudomonas aeruginosa isolated in an Italian survey J Antimicrob Chemother 42 1998 697 702
9. S. Lanini, S. D'Arezzo, V. Puro, L. Martini, F. Imperi, and P. Piselli Molecular epidemiology of a Pseudomonas aeruginosa hospital outbreak driven by a contaminated disinfectant-soap dispenser PLoS One 6 2011
10. D.G. Davies, M.R. Parsek, J.P. Pearson, B.H. Iglewski, J.W. Costerton, and E.P. Greenberg The involvement of cell-to-cell signals in the development of a bacterial biofilm Science 280 1998 295 298
11. W.L. Ng, and B.L. Bassler Bacterial quorum-sensing network architectures 2009 197 222
12. C.M. Waters, and B.L. Bassler Quorum sensing: cell-to-cell communication in bacteria 2005 319 346
13. T.B. Rasmussen, and M. Givskov Quorum-sensing inhibitors as anti-pathogenic drugs Int J Med Microbiol 296 2006 149 161
14. R. Kumar, S. Chhibber, and K. Harjai Quorum sensing is necessary for the virulence of Pseudomonas aeruginosa during urinary tract infection Kidney Int 76 2009 286 292
15. R.J. Ulevitch, and P.S. Tobias Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin Annu Rev Immunol 13 1995 437 457
16. A. MacGowan, and E. Macnaughton Antibiotic resistance Medicine (U K) 41 2013 642 648
17. E.C. Pesci, J.P. Pearson, P.C. Seed, and B.H. Iglewski Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa J Bacteriol 179 1997 3127 3132
18. Y. Xu, K. Duan, and L. Shen Quorum sensing in Pseudomonas aeruginosa J Pure Appl Microbiol 7 2013 2003 2015
19. V.E. Wagner, D. Bushnell, L. Passador, A.I. Brooks, and B.H. Iglewski Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment J Bacteriol 185 2003 2080 2095
20. J.J. Lazenby, P.E. Griffin, J. Kyd, C.B. Whitchurch, and M.A. Cooley A quadruple knockout of lasIR and rhlIR of Pseudomonas aeruginosa PAO1 that retains wild-type twitching motility has equivalent infectivity and persistence to PAO1 in a mouse model of lung infection PLoS One 8 2013
21. V. Naik, and G. Mahajan Quorum sensing: a non-conventional target for antibiotic discovery Nat Prod Commun 8 2013 1455 1458
22. M. Henkel, A. Schmidberger, C. Kühnert, J. Beuker, T. Bernard, and T. Schwartz Kinetic modeling of the time course of N-butyryl-homoserine lactone concentration during batch cultivations of Pseudomonas aeruginosa PAO1 Appl Microbiol Biotechnol 2013 1 10
23. P.C. Shih, and C.T. Huang Effects of quorum-sensing deficiency on Pseudomonas aeruginosa biofilm formation and antibiotic resistance J Antimicrob Chemother 49 2002 309 314
24. A. Annapoorani, V. Umamageswaran, R. Parameswari, S.K. Pandian, and A.V. Ravi Computational discovery of putative quorum sensing inhibitors against LasR and RhlR receptor proteins of Pseudomonas aeruginosa J Comput Aided Mol Des 26 2012 1067 1077
25. D.A. Vattem, K. Mihalik, S.H. Crixell, and R.J.C. McLean Dietary phytochemicals as quorum sensing inhibitors Fitoterapia 78 2007 302 310
26. E. Tjendraputra, V.H. Tran, D. Liu-Brennan, B.D. Roufogalis, and C.C. Duke Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells Bioorg Chem 29 2001 156 163
27. L. Kumar, S. Chhibber, and K. Harjai Zingerone inhibit biofilm formation and improve antibiofilm efficacy of ciprofloxacin against Pseudomonas aeruginosa PAO1 Fitoterapia 90 2013 73 78
28. H. Sies, and H. Masumoto Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite Adv Pharmacol (San Diego, Calif) 38 1997 229 246
29. L. Kumar, S. Chhibber, and K. Harjai Structural alterations in Pseudomonas aeruginosa by zingerone contribute to enhanced susceptibility to antibiotics, serum and phagocytes Life Sci 117 2014 24 32
30. J.H. Choo, Y. Rukayadi, and J.K. Hwang Inhibition of bacterial quorum sensing by vanilla extract Lett Appl Microbiol 42 2006 637 641
31. R. Kumar, S. Chhibber, V. Gupta, and K. Harjai Screening & profiling of quorum sensing signal molecules in Pseudomonas aeruginosa isolates from catheterized urinary tract infection patients Indian J Med Res 134 2011 208 213
32. A. Bala, R. Kumar, and K. Harjai Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections J Med Microbiol 60 2011 300 306
33. A. Bala, R.K. Gupta, S. Chhibber, and K. Harjai Detection and quantification of quinolone signalling molecule: a third quorum sensing molecule of Pseudomonas aeruginosa by high performance-thin layer chromatography J Chromatogr B Analyt Technol Biomed Life Sci 930 2013 30 35
34. V. Huerta, K. Mihalik, S.H. Crixell, and D.A. Vattem Herbs, spices and medicinal plants used in Hispanic traditional medicine can decrease quorum sensing dependent virulence in Pseudomonas aeruginosa Int J Appl Res Nat Prod 1 2008 9 15
35. P.G. Lankisch, and W. Vogt Direct haemolytic activity of phospholipase A, Biochimica et Biophysica Acta (BBA)/lipids and lipid Metabolism 270 1972 241 247
36. P. Visca, G. Colotti, L. Serino, D. Verzili, N. Orsi, and E. Chiancone Metal regulation of siderophore synthesis in Pseudomonas aeruginosa and functional effects of siderophore-metal complexes Appl Environ Microbiol 58 1992 2886 2893
37. H. Zhu, S.J. Thuruthyil, and M.D.P. Willcox Determination of quorum-sensing signal molecules and virulence factors of Pseudomonas aeruginosa isolates from contact lens-induced microbial keratitis J Med Microbiol 51 2002 1063 1070
38. M. Kelsey Pseudomonas in augmented care: should we worry? J Antimicrob Chemother 68 2013 2697 2700
39. A.R. Hauser Pseudomonas aeruginosa virulence and antimicrobial resistance: two sides of the same coin? Crit Care Med 42 2014 201 202
40. I. Blus-Kadosh, A. Zilka, G. Yerushalmi, and E. Banin The effect of pstS and phoB on quorum sensing and swarming motility in Pseudomonas aeruginosa PLoS One 8 2013
41. M. Klausen, A. Heydorn, P. Ragas, L. Lambertsen, A. Aaes-Jørgensen, and S. Molin Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants Mol Microbiol 48 2003 1511 1524
42. Q. Guo, W. Kong, S. Jin, L. Chen, Y. Xu, and K. Duan PqsR-dependent and PqsR-independent regulation of motility and biofilm formation by PQS in Pseudomonas aeruginosa PAO1 J Basic Microbiol 54 2014 633 643
43. J. Manos, H. Hu, B.R. Rose, C.E. Wainwright, I.B. Zablotska, and J. Cheney Virulence factor expression patterns in Pseudomonas aeruginosa strains from infants with cystic fibrosis Eur J Clin Microbiol Infect Dis 32 2013 1583 1592
44. B. Rada, and T.L. Leto Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections Trends Microbiol 21 2013 73 81
45. G.J. Pacheco, R.S. Reis, A.C.L.B. Fernandes, S.L.G. Da Rocha, M.D. Pereira, and J. Perales Rhamnolipid production: effect of oxidative stress on virulence factors and proteome of Pseudomonas aeruginosa PA1 Appl Microbiol Biotechnol 95 2012 1519 1529
46. M.K. Kim, S.W. Chung, D.H. Kim, J.M. Kim, E.K. Lee, and J.Y. Kim Modulation of age-related NF-κB activation by dietary zingerone via MAPK pathway Exp Gerontol 45 2010 419 426
47. B.N. Rao, P.R. Archana, B.K. Aithal, and B.S.S. Rao Protective effect of zingerone, a dietary compound against radiation induced genetic damage and apoptosis in human lymphocytes Eur J Pharmacol 657 2011 59 66