Probing phase transitions in simvastatin with terahertz time-domain spectroscopy

Molecular Pharmaceutics

Volumn 12, Issue 3, 2015, Pages 810-815

  Tan, Nicholas Y ^a   Zeitler, J Axel ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

disordered crystal; phase transition; simvastatin; spectroscopy; terahertz

Indexed keywords

SIMVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ABSORPTION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG POLYMORPHISM; DRUG STRUCTURE; HEATING; HYDROGEN BOND; MOTION; PHASE TRANSITION; PRIORITY JOURNAL; SPECTRUM; TEMPERATURE DEPENDENCE; TERAHERTZ RADIATION; TERAHERTZ SPECTROSCOPY; VIBRATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; HUMAN; MOLECULAR DYNAMICS; PHARMACEUTICS; TEMPERATURE;

BIOPHARMACEUTICS; HUMANS; HYDROGEN BONDING; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MOTION; PHASE TRANSITION; SIMVASTATIN; TEMPERATURE; TERAHERTZ SPECTROSCOPY; VIBRATION;

EID: 84923925128     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500649q     Document Type: Article

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