Over-expression of telomere binding factors (TRF1 & TRF2) in renal cell carcinoma and their inhibition by using SiRNA induce apoptosis, reduce cell proliferation and migration invitro

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Pal, Deeksha ^a   Sharma, Ujjawal ^a   Singh, Shrawan Kumar ^a   Kakkar, Nandita ^a   Prasad, Rajendra ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SMALL INTERFERING RNA; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2;

ADULT; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG TARGETING; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PROTEIN EXPRESSION; RENAL CELL CARCINOMA CELL LINE; UPREGULATION; AGED; ANTAGONISTS AND INHIBITORS; CELL MOTION; G1 PHASE CELL CYCLE CHECKPOINT; GENETICS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TUMOR; METABOLISM; PATHOLOGY; S PHASE CELL CYCLE CHECKPOINT; TUMOR CELL LINE;

ADULT; AGED; APOPTOSIS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; RNA, SMALL INTERFERING; S PHASE CELL CYCLE CHECKPOINTS; TELOMERIC REPEAT BINDING PROTEIN 1; TELOMERIC REPEAT BINDING PROTEIN 2; UP-REGULATION;

EID: 84923875913     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115651     Document Type: Article

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