Hepatitis C virus attenuates mitochondrial lipid β-oxidation by downregulating mitochondrial trifunctional-protein expression

Journal of Virology

Volumn 89, Issue 8, 2015, Pages 4092-4101

  Amako, Yutaka ^a,b   Munakata, Tsubasa ^b   Kohara, Michinori ^b   Siddiqui, Aleem ^c   Peers, Chris ^a   Harris, Mark ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; MESSENGER RNA; MITOCHONDRIAL TRIFUNCTIONAL PROTEIN; LUCIFERASE; SMALL INTERFERING RNA;

ARTICLE; CATALYSIS; CELL LINE; CELL METABOLISM; CONTROLLED STUDY; DOWN REGULATION; ENERGY YIELD; FATTY ACID OXIDATION; GENE EXPRESSION; HEPATITIS C; HEPATITIS C VIRUS; HOMEOSTASIS; HUH7.5 CELL LINE; HUMAN; HUMAN CELL; INNATE IMMUNITY; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; HEPACIVIRUS; HOST PATHOGEN INTERACTION; LIPID METABOLISM; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

HEPATITIS C VIRUS;

BLOTTING, WESTERN; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEPACIVIRUS; HEPATITIS C; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON-ALPHA; LIPID METABOLISM; LUCIFERASES; MITOCHONDRIAL TRIFUNCTIONAL PROTEIN; OXIDATION-REDUCTION; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84923875260     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01653-14     Document Type: Article

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