Depth-dependent changes in collagen organization in the human peripapillary sclera

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Pijanka, Jacek K ^a   Spang, Martin T ^a   Sorensen, Thomas ^b   Liu, Jun ^c   Nguyen, Thao D ^d   Quigley, Harry A ^e   Boote, Craig ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b DIAMOND LIGHT SOURCE LTD   (United Kingdom)

^c Ohio State University   (United States)

^d Johns Hopkins University   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOTROPY; ARTICLE; CHOROID; COLLAGEN FIBRIL; COLLAGEN SYNTHESIS; CONTROLLED STUDY; EUROPEAN; GLAUCOMA; HUMAN; HUMAN TISSUE; INTRAOCULAR PRESSURE; MEMBRANE STRUCTURE; OPTIC NERVE; PERIPAPILLARY SCLERA; SCLERA; SMALL ANGLE SCATTERING; STROMA; TISSUE SECTION; WIDE ANGLE X RAY SCATTERING; X RAY CRYSTALLOGRAPHY; AGED; BIOLOGICAL MODEL; BIOMECHANICS; METABOLISM; MIDDLE AGED; OPTIC DISK; PATHOPHYSIOLOGY;

COLLAGEN;

AGED; ANISOTROPY; BIOMECHANICAL PHENOMENA; COLLAGEN; HUMANS; MIDDLE AGED; MODELS, BIOLOGICAL; OPTIC DISK; SCLERA;

EID: 84923862231     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118648     Document Type: Article

References (33)

1. Watson PG, Young RD. Scleral structure, organisation and disease. A review. Experimental Eye Research. 2004; 78(3):609-23. PMID: 15106941
2. Komai Y, Ushiki T. The three-dimensional organisation of collagen fibrils in the human cornea and sclera. Investigative Ophthalmology and Visual Science. 1991; 32(8):2244-58. PMID: 2071337
3. Kokott W. Das spaltlinienbild der sklera (Ein beitrag zum funktionellen bau der sklera) Klin Monbl Augenheilkd. 1934; 92:177-85.
4. Pijanka JK, Abass A, Sorensen T, Elsheikh A, Boote C. A wide-angle X-ray fibre diffraction method for quantifying collagen orientation across large tissue areas: application to the human eyeball coat. Journal of Applied Crystallography. 2013; 46:1481-9. doi: 10.1107/s0021889813022358 PMID: WOS:000324764500028.
5. Morrison JC, Lhernault NL, Jerdan JA, Quigley HA. Ultrastructural Location of Extracellular-Matrix Components in the Optic Nerve Head. Archives of Ophthalmology. 1989; 107(1):123-9. PMID: WOS: A1989R752500034.
6. Pijanka JK, Coudrillier B, Ziegler K, Sorensen T, Meek KM, Nguyen TD, et al. Quantitative mapping of collagen fiber orientation in non-glaucoma and glaucoma posterior human sclerae. Invest Ophthalmol Vis Sci. 2012; 53(9):5258-70. Epub 2012/07/13. doi: 10.1167/iovs.12-9705 PMID: 22786908; PubMed Central PMCID: PMC3416032.
7. Winkler M, Jester B, Nien-Shy C, Massei S, Minckler DS, Jester JV, et al. High resolution three-dimensional reconstruction of the collagenous matrix of the human optic nerve head. Brain Research Bulletin. 2010; 81(2-3):339-48. doi: 10.1016/j.brainresbull.2009.06.001 PMID: WOS:000274610500019.
8. Tektas OY, Lutjen-Drecoll E, Scholz M. Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG. Invest Ophthalmol Vis Sci. 2010; 51(10):5083-91. Epub 2010/05/21. doi: 10.1167/iovs.09-5101 PMID: 20484598.
9. Quigley HA, Brown A, Dorman-Pease ME. Alterations in elastin of the optic nerve head in human and experimental glaucoma. Br J Ophthalmol. 1991; 75(9):552-7. Epub 1991/09/01. PMID: 1911659.
10. Coudrillier B, Boote C, Quigley HA, Nguyen TD. Scleral anisotropy and its effects on the mechanical response of the optic nerve head. Biomech Model Mechanobiol. 2013; 12(5):941-63. Epub 2012/11/29. doi: 10.1007/s10237-012-0455-y PMID: 23188256; PubMed Central PMCID: PMC3615129.
11. Girard MJ, Downs JC, Burgoyne CF, Suh JK. Peripapillary and posterior scleral mechanics-part I: development of an anisotropic hyperelastic constitutive model. J Biomech Eng. 2009; 131(5):051011. Epub 2009/04/25. doi: 10.1115/1.3113682 PMID: 19388781.
12. Grytz R, Fazio MA, Girard MJ, Libertiaux V, Bruno L, Gardiner S, et al. Material properties of the posterior human sclera. J Mech Behav Biomed Mater. 2014; 29:602-17. Epub 2013/05/21. doi: 10.1016/j. jmbbm.2013.03.027 PMID: 23684352; PubMed Central PMCID: PMC3778040.
13. Yan D, McPheeters S, Johnson G, Utzinger U, Vande Geest JP. Microstructural differences in the human posterior sclera as a function of age and race. Invest Ophthalmol Vis Sci. 2011; 52(2):821-9. Epub 2010/11/06. doi: 10.1167/iovs.09-4651 PMID: 21051726; PubMed Central PMCID: PMC3262314.
14. Danford FL, Yan D, Dreier RA, Cahir TM, Girkin CA, Vande Geest JP. Differences in the region- and depth-dependent microstructural organization in normal versus glaucomatous human posterior sclerae. Invest Ophthalmol Vis Sci. 2013; 54(13):7922-32. Epub 2013/11/10. doi: 10.1167/iovs.13-12262 PMID: 24204041; PubMed Central PMCID: PMC3850668.
15. Girard MJ, Dahlmann-Noor A, Rayapureddi S, Bechara JA, Bertin BM, Jones H, et al. Quantitative mapping of scleral fiber orientation in normal rat eyes. Invest Ophthalmol Vis Sci. 2011; 52(13):9684-93. doi: 10.1167/iovs.11-7894 PMID: 22076988
16. Boote C, Dennis S, Huang Y, Meek K. Lamellar orientation in human cornea in relation to mechanical properties. Journal of Structural Biology. 2005; 149(1):1-6. PMID: 15629652
17. Boote C, Hayes S, Abahussin M, Meek KM. Mapping collagen organisation in the human cornea: left and right eyes are structurally distinct. Invest Ophthalmol Vis Sci. 2006; 47(3):901-8. PMID: 16505022
18. Meek KM, Boote C. The use of x-ray scattering techniques to quantify the orientation and distribution of collagen in the corneal stroma. Prog Retin Eye Res. 2009; 28(5):369-92. PMID: 19577657. doi: 10. 1016/j.preteyeres.2009.06.005
19. Ren R, Wang N, Li B, Li L, Gao F, Xu X, et al. Lamina cribrosa and peripapillary sclera histomorphometry in normal and advanced glaucomatous Chinese eyes with various axial length. Invest Ophthalmol Vis Sci. 2009; 50(5):2175-84. Epub 2009/04/24. doi: 10.1167/iovs.07-1429 PMID: 19387083.
20. Sigal IA, Flanagan JG, Tertinegg I, Ethier CR. 3D morphometry of the human optic nerve head. Exp Eye Res. 2010; 90(1):70-80. Epub 2009/09/24. doi: 10.1016/j.exer.2009.09.013 PMID: 19772858.
21. Wang L, Yang H, Kankipati L, Downs JC, Burgoyne CF, Girkin CA. Three-Dimesional Histomorphometric Reconstructions of Regional Variation of Lamina Cribrosa Insertion into the Neural Canal in Normal Human Eyes. ARVO Abstract. 2012; 53:2814.
22. Quigley HA, Addicks EM, Green WR, Maumenee AE. Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol. 1981; 99(4):635-49. Epub 1981/04/01. PMID: 6164357.
23. Coudrillier B, Tian J, Alexander S, Myers KM, Quigley HA, Nguyen TD. Mechanical response of the human posterior sclera: age and glaucoma related changes measured using inflation testing. Invest Ophthalmol Vis Sci. 2012; 53(4):1714-28. doi: 10.1167/iovs.11-8009 PMID: 22395883.
24. Quigley HA, Dorman-Pease ME, Brown AE. Quantitative study of collagen and elastin of the optic nerve head and sclera in human and experimental monkey glaucoma. Curr Eye Res. 1991; 10(9):877-88. PMID: 1790718.
25. Sigal IA, Flanagan JG, Lathrop KL, Tertinegg I, Bilonick R. Human lamina cribrosa insertion and age. Invest Ophthalmol Vis Sci. 2012; 53(11):6870-9. Epub 2012/09/08. doi: 10.1167/iovs.12-9890 PMID: 22956611; PubMed Central PMCID: PMC3466065.
26. Liu J, Tang J, Hart R, Roberts C, Weber P, Pan X. Through-thickness variation of human scleral strains in response to IOP elevation measured by ultrasound speckle tracking. ARVO Abstract. 2013; 54:77.
27. Morris HJ, Tang J, Cruz Perez B, Pan X, Hart RT, Weber PA, et al. Correlation between biomechanical responses of posterior sclera and IOP elevations during micro intraocular volume change. Invest Ophthalmol Vis Sci. 2013; 54(12):7215-22. Epub 2013/10/17. doi: 10.1167/iovs.13-12441 PMID: 24130185; PubMed Central PMCID: PMC3816617.
28. Tang J, Liu J. Ultrasonic measurement of scleral cross-sectional strains during elevations of intraocular pressure: method validation and initial results in posterior porcine sclera. J Biomech Eng. 2012; 134 (9):091007. Epub 2012/09/04. doi: 10.1115/1.4007365 PMID: 22938374.
29. Yamamoto S, Hashizume H, Hitomi J, Shigeno M, Sawaguchi S, Abe H, et al. The subfibrillar arrangement of corneal and scleral collagen fibrils as revealed by scanning electron and atomic force microscopy. Archives of Histology and Cytology. 2000; 63(2):127-35. PMID: 10885449
30. McBrien NA, Jobling AI, Gentle A. Biomechanics of the sclera in myopia: extracellular and cellular factors. Optom Vis Sci. 2009; 86(1):E23-30. doi: 10.1097/OPX.0b013e3181940669 PMID: 19104466
31. Rada JAS, Shelton S, Norton TT. The sclera and myopia. Experimental Eye Research. 2006; 82 (2):185-200. doi: 10.1016/j.exer.2005.08.009 PMID: WOS:000235260800002.
32. Lanir Y. Mechanisms of residual stress in soft tissues. J Biomech Eng. 2009; 131(4):044506. Epub 2009/03/12. doi: 10.1115/1.3049863 PMID: 19275448.
33. Kotecha A, Izadi S, Jeffery G. Age-related changes in the thickness of the human lamina cribrosa. Br J Ophthalmol. 2006; 90(12):1531-4. Epub 2006/09/01. doi: 10.1136/bjo.2006.100388 PMID: 16943226; PubMed Central PMCID: PMC1857539.