Physicians need to take the lead in deprescribing

Internal Medicine Journal

Volumn 45, Issue 3, 2015, Pages 352-356

  Scott, I A ^a,b   Le Couteur, D G ^c,d  

^a PRINCESS ALEXANDRA HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c ANZAC Research Institute   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Deprescribing; Harm; Medicine; Older patient; Polypharmacy

Indexed keywords

ARTICLE; AWARENESS; CLINICAL PRACTICE; COMMUNICATION SKILL; DEPRESCRIBING; DRUG COST; GENERAL PRACTITIONER; GERIATRIC CARE; HIGH RISK POPULATION; HUMAN; INAPPROPRIATE PRESCRIBING; MEDICAL EDUCATION; MEDICAL RECORD; PATIENT CARE; PHYSICIAN; POLYPHARMACY; POSTMARKETING SURVEILLANCE; PRACTICE GUIDELINE; PRESCRIPTION; PRIORITY JOURNAL; PROFESSIONAL DEVELOPMENT; PROFESSIONAL KNOWLEDGE; SELF CONCEPT; SYSTEMATIC REVIEW; TERMINAL CARE; WITHDRAWAL SYNDROME; DEPRESCRIPTION; HEALTH SERVICE; LEADERSHIP; PHYSICIAN ATTITUDE; PREVENTION AND CONTROL; STANDARDS; TRENDS;

DEPRESCRIPTIONS; DRUG PRESCRIPTIONS; HEALTH SERVICES NEEDS AND DEMAND; HUMANS; INAPPROPRIATE PRESCRIBING; LEADERSHIP; PHYSICIAN'S ROLE; POLYPHARMACY;

EID: 84923766126     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/imj.12693     Document Type: Article

References (35)

1. Glasziou P, Moynihan R, Richards T, Godlee F. Too much medicine; too little care. BMJ 2013; 347: f4247.
2. Wise J. Polypharmacy: a necessary evil. BMJ 2013; 347: f7033.
3. Barry PJ, Gallagher P, Ryan C, O'Mahony D. START (screening tool to alert doctors to the right treatment) - an evidence-based screening tool to detect prescribing omissions in elderly patients. Age Ageing 2007; 36: 632-638.
4. Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007; 5: 345-351.
5. Huang AR, Mallet L, Rochefort CM, Eguale T, Buckeridge DL, Tamblyn R. Medication related falls in the elderly: causative factors and preventive strategies. Drugs Aging 2012; 29: 359-376.
6. Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med 2011; 365: 2002-2012.
7. Jyrkka J, Enlund H, Korhonen MJ, Sulkava R, Hartikainen S. Polypharmacy status as an indicator of mortality in an elderly population. Drugs Aging 2009; 26: 1039-1048.
8. Kalisch LM, Caughey GE, Barratt JD, Ramsay EN, Killer G, Gilbert AL etal. Prevalence of preventable medication-related hospitalizations in Australia: an opportunity to reduce harm. Int J Qual Health Care 2012; 24: 239-249.
9. Miller GC, Britth HC, Valenti L. Adverse drug events in general practice patients in Australia. Med J Aust 2006; 184: 321-324.
10. Stafford AC, Alswayan MS, Tenni PC. Inappropriate prescribing in older residents of Australian care homes. J Clin Pharmacol Ther 2011; 36: 33-44.
11. Somers M, Rose E, Simmonds D, Whitelaw C, Calver J, Beer C. Quality use of medicines in residential aged care. Aust Fam Physician 2010; 39: 413-416.
12. Roughead EE, Anderson B, Gilbert AL. Potentially inappropriate prescribing among Australian veterans and war widows/widowers. Intern Med J 2007; 37: 402-405.
13. Finch AJ, McKean M, Pillans P, Scott IA Pilot study of a drug minimisation guide applied to older patients in hospital. Proceedings of the Australian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Melbourne, 2013.
14. Lindsay J, Dooley M, Martin J, Fay M, Kearney A, Barras M. Reducing potentially inappropriate medications in palliative cancer patients: evidence to support deprescribing approaches. Support Care Cancer 2014; 22: 1113-1119.
15. Australian Commission on Safety and Quality in Health Care. Literature Review: Medication Safety in Australia. Sydney: ACSQHC; 2013.
16. Alldred DP. Deprescribing: a brave new word? Int J Pharm Pract 2014; 22: 2-3.
17. Betteridge TM, Frampton CM, Jardine DL. Polypharmacy - we make it worse! A cross-sectional study from an acute admissions unit. Intern Med J 2012; 42: 208-211.
18. Klopotowska JE, Wierenga PC, Smorenburg SM, Stuijt CC, Arisz L, Kuks PF etal. Recognition of adverse drug events in older hospitalized medical patients. Eur J Clin Pharmacol 2013; 69: 75-85.
19. Anderson K, Freeman C, Stowasser D, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open 2014; 4: e006544.
20. Zulman DM, Sussman JB, Chen X, Cigolle CT, Blaum CS, Hayward RA. Examining the evidence: a systematic review of the inclusion and analysis of older adults in randomized controlled trials. J Gen Intern Med 2011; 26: 783-790.
21. Vitry AI, Zhang Y. Quality of Australian clinical guidelines and relevance to the care of older people with multiple comorbid conditions. Med J Aust 2008; 189: 360-365.
22. Sachs GA. Improving prescribing practices late in life. A task for all clinicians, not just nursing home physicians. JAMA Intern Med 2014; 174: 1771-1772.
23. Robertson J, Treloar CJ, Sprogis A, Henry DA. The influence of specialists on prescribing by GPs. A qualitative study. Aust Fam Physician 2003; 32: 573-576.
24. Iyer S, Naganathan V, McLachlan AJ, Le Couteur DG. Medication withdrawal trials in people aged 65 years and older: a systematic review. Drugs Aging 2008; 25: 1021-1031.
25. Gnjidic D, Le Couteur DG, Kouladjian L, Hilmer SN. Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes. Clin Geriatr Med 2012; 28: 237-253.
26. Declercq T, Petrovic M, Azermai M, Vander Stichele R, De Sutter AI, van Driel ML etal. Withdrawal versus continuation of chronic antipsychotic medicines for behavioural and psychological symptoms in older people with dementia. Cochrane Database Syst Rev 2013; (3): CD007726.
27. Gallagher PF, O'Connor MN, O'Mahony D. Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria. Clin Pharmacol Ther 2011; 89: 845-854.
28. Scott IA, Gray LC, Martin JH, Mitchell CA. Minimizing inappropriate medicines in older populations: a 10-step conceptual framework. Am J Med 2012; 125: 529-537.
29. Hilmer SN, Gnjidic D, Le Couteur DG. Thinking through the medication list. Appropriate prescribing and deprescribing in robust and frail older patients. Aust Fam Phys 2012; 41: 924-928.
30. Reeve E, Shakib S, Hendrix I, Roberts MS, Wiese MD. Review of deprescribing processes and development of an evidence based, patient-centred deprescribing process. Br J Clin Pharmacol 2014; 78: 738-747.
31. Garfinkel D, Mangin D. Feasibility study of a systematic approach for discontinuation of multiple medicines in older adults: addressing polypharmacy. Arch Intern Med 2010; 170: 1648-1654.
32. Scott IA, Gray LC, Martin JH, Mitchell CA. Effects of a drug minimization guide on prescribing intentions in elderly persons with polypharmacy. Drugs Aging 2012; 29: 659-667.
33. NPS MedicineWise. Older, wiser, safer. MedicineWise news. 2013 [cited 2014 Sep 12]. Available from URL: http://www.nps.org.au/publications/health-professional/medicinewise-news/2013/older-wiser-safer
34. Best Practice Advocacy Centre for New Zealand. A practical guide to stopping medicines in older people. 2010; [cited 2014 Jul 11]. Available from URL: http://www.bpac.org.nz/magazine/2010/april/stopGuide.asp
35. Phillipe Pinel - the Father of Modern Psychiatry. Treatise on insanity, 1806. [cited 2014 Sep 19]. Available from URL: http://geniusrevive.com/en/geniuses.html?pid=82&sid=267:philippe-pinel-the-father-of-modern-psychiatry