-
1
-
-
30844464790
-
The measurement and clinical relevance of brain atrophy in multiple sclerosis
-
Bermel RA, Bakshi R. The measurement and clinical relevance of brain atrophy in multiple sclerosis. Lancet Neurol 2006;5:158-170
-
(2006)
Lancet Neurol
, vol.5
, pp. 158-170
-
-
Bermel, R.A.1
Bakshi, R.2
-
2
-
-
77953335345
-
Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes
-
De Stefano N, Giorgio A, Battaglini M, et al. Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes. Neurology 2010;74:1868-1876
-
(2010)
Neurology
, vol.74
, pp. 1868-1876
-
-
De Stefano, N.1
Giorgio, A.2
Battaglini, M.3
-
3
-
-
84885413852
-
Evolution of cortical and thalamus atrophy and disability progression in early relapsing-remitting MS during 5 years
-
Zivadinov R, Bergsland N, Dolezal O, et al. Evolution of cortical and thalamus atrophy and disability progression in early relapsing-remitting MS during 5 years. Am J Neuroradiol 2013;34:1931-1939
-
(2013)
Am J Neuroradiol
, vol.34
, pp. 1931-1939
-
-
Zivadinov, R.1
Bergsland, N.2
Dolezal, O.3
-
4
-
-
0034700989
-
Progressive cerebral atrophy in MS: A serial study using registered, volumetric MRI
-
Fox NC, Jenkins R, Leary SM, et al. Progressive cerebral atrophy in MS: a serial study using registered, volumetric MRI. Neurology 2000;54:807-812
-
(2000)
Neurology
, vol.54
, pp. 807-812
-
-
Fox, N.C.1
Jenkins, R.2
Leary, S.M.3
-
5
-
-
0033544320
-
Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group
-
Rudick RA, Fisher E, Lee JC, Simon J, Jacobs L. Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group. Neurology 1999;53:1698-1704
-
(1999)
Neurology
, vol.53
, pp. 1698-1704
-
-
Rudick, R.A.1
Fisher, E.2
Lee, J.C.3
Simon, J.4
Jacobs, L.5
-
6
-
-
38349081521
-
Brain volume decline in aging: Evidence for a relation between socioeconomic status, preclinical Alzheimer disease, and reserve
-
Fotenos AF, Mintun MA, Snyder AZ, Morris JC, Buckner RL. Brain volume decline in aging: evidence for a relation between socioeconomic status, preclinical Alzheimer disease, and reserve. Arch Neurol 2008;65: 113-120
-
(2008)
Arch Neurol
, vol.65
, pp. 113-120
-
-
Fotenos, A.F.1
Mintun, M.A.2
Snyder, A.Z.3
Morris, J.C.4
Buckner, R.L.5
-
7
-
-
84908326865
-
Brain atrophy and disability progression in multiple sclerosis patients: A 10-year follow-up study
-
Jacobsen C, Hagemeier J, Myhr KM, et al. Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study. J Neurol Neurosurg Psychiatry 2014;85:1109-1115
-
(2014)
J Neurol Neurosurg Psychiatry
, vol.85
, pp. 1109-1115
-
-
Jacobsen, C.1
Hagemeier, J.2
Myhr, K.M.3
-
8
-
-
0036342788
-
Measurement of atrophy in multiple sclerosis: Pathological basis, methodological aspects and clinical relevance
-
Miller DH, Barkhof F, Frank JA, Parker GJ, Thompson AJ. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain 2002;125:1676-1695
-
(2002)
Brain
, vol.125
, pp. 1676-1695
-
-
Miller, D.H.1
Barkhof, F.2
Frank, J.A.3
Parker, G.J.4
Thompson, A.J.5
-
9
-
-
2942647959
-
Central nervous system atrophy and clinical status in multiple sclerosis
-
Zivadinov R, Bakshi R. Central nervous system atrophy and clinical status in multiple sclerosis. J Neuroimaging 2004;14:27S-35S
-
(2004)
J Neuroimaging
, vol.14
, pp. 27S-35S
-
-
Zivadinov, R.1
Bakshi, R.2
-
10
-
-
0037069230
-
Eight-year followup study of brain atrophy in patients with MS
-
Fisher E, Rudick RA, Simon JH, et al. Eight-year followup study of brain atrophy in patients with MS. Neurology 2002;59:1412-1420
-
(2002)
Neurology
, vol.59
, pp. 1412-1420
-
-
Fisher, E.1
Rudick, R.A.2
Simon, J.H.3
-
11
-
-
84894038191
-
Treatment effect on brain atrophy correlates with treatment effect on disability in multiple sclerosis
-
Sormani MP, Arnold DL, De Stefano N. Treatment effect on brain atrophy correlates with treatment effect on disability in multiple sclerosis. Ann Neurol 2014;75: 43-49
-
(2014)
Ann Neurol
, vol.75
, pp. 43-49
-
-
Sormani, M.P.1
Arnold, D.L.2
De Stefano, N.3
-
12
-
-
84879774740
-
Preventing brain atrophy should be the gold standard of effective therapy in MS (after the first year of treatment): Yes
-
Rudick RA, Fisher E. Preventing brain atrophy should be the gold standard of effective therapy in MS (after the first year of treatment): yes. Mult Scler 2013;19:1003-1004
-
(2013)
Mult Scler
, vol.19
, pp. 1003-1004
-
-
Rudick, R.A.1
Fisher, E.2
-
13
-
-
84863344656
-
Association between pathological and MRI findings in multiple sclerosis
-
Filippi M, Rocca MA, Barkhof F, et al. Association between pathological and MRI findings in multiple sclerosis. Lancet Neurol 2012;11:349-360
-
(2012)
Lancet Neurol
, vol.11
, pp. 349-360
-
-
Filippi, M.1
Rocca, M.A.2
Barkhof, F.3
-
14
-
-
76149093586
-
A placebocontrolled trial of oral fingolimod in relapsing multiple sclerosis
-
Kappos L, Radue EW, O'Connor P, et al. A placebocontrolled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med 2010;362:387-401
-
(2010)
N Engl J Med
, vol.362
, pp. 387-401
-
-
Kappos, L.1
Radue, E.W.2
O'connor, P.3
-
15
-
-
84901197534
-
Efficacy and safety of fingolimod in patients with relapsing-remitting multiple sclerosis: Results from the 24-month phase 3 double-blind, randomised, placebo-controlled study (FREEDOMS II)
-
Calabresi PA, Radue EW, Goodin D, et al. Efficacy and safety of fingolimod in patients with relapsing-remitting multiple sclerosis: results from the 24-month phase 3 double-blind, randomised, placebo-controlled study (FREEDOMS II). Lancet Neurol 2014;13:545-556
-
(2014)
Lancet Neurol
, vol.13
, pp. 545-556
-
-
Calabresi, P.A.1
Radue, E.W.2
Goodin, D.3
-
16
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen JA, Barkhof F, Comi G, et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 2010;362:402-415
-
(2010)
N Engl J Med
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
-
17
-
-
79956024142
-
Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: A randomised extension of the TRANSFORMS Study
-
Khatri B, Barkhof F, Comi G, et al. Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS Study. Lancet Neurol 2011;10:520-529
-
(2011)
Lancet Neurol
, vol.10
, pp. 520-529
-
-
Khatri, B.1
Barkhof, F.2
Comi, G.3
-
18
-
-
84894272443
-
Switching therapy to fingolimod improves clinical and MRI outcomes: Subgroup analysis from the fingolimod phase III FREEDOMS extension (up to 4 years) study
-
P619
-
Kappos L, Radue EW, O'Connor P, et al. Switching therapy to fingolimod improves clinical and MRI outcomes: subgroup analysis from the fingolimod phase III FREEDOMS extension (up to 4 years) study. Mult Scler 2013; 19(11 suppl):74-558. P619
-
(2013)
Mult Scler
, vol.19
, Issue.11
, pp. 74-558
-
-
Kappos, L.1
Radue, E.W.2
O'connor, P.3
-
19
-
-
84938374065
-
Long-term efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis: Results from the phase 3 FREEDOMS II extension study
-
P1092
-
Reder AT, Jeffery D, Goodin D, et al. Long-term efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis: results from the phase 3 FREEDOMS II extension study. Mult Scler 2013;19(11 suppl):74-558. P1092
-
(2013)
Mult Scler
, vol.19
, Issue.11
, pp. 74-558
-
-
Reder, A.T.1
Jeffery, D.2
Goodin, D.3
-
20
-
-
84964594016
-
International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use: Ich harmonised tripartite guideline
-
International Conference on Harmonisation. Accessed January 17
-
International Conference on Harmonisation. International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use: ICH Harmonised Tripartite Guideline. Guideline for Good Clinical Practice. Available at: http://www.ich.org/ fileadmin/Public-Web-Site/ICH-Products/Guidelines/ Efficacy/E6/E6-R1-Guideline.pdf. Accessed January 17, 2014
-
(2014)
Guideline for Good Clinical Practice
-
-
-
22
-
-
0036742197
-
Accurate, robust, and automated longitudinal and cross-sectional brain change analysis
-
Smith SM, Zhang Y, Jenkinson M, et al. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 2002;17:479-489
-
(2002)
Neuroimage
, vol.17
, pp. 479-489
-
-
Smith, S.M.1
Zhang, Y.2
Jenkinson, M.3
-
23
-
-
84908265861
-
The influence of patient demographics, disease characteristics and treatment on brain volume loss in Trial Assessing Injectable Interferon vs FTY720 Oral in Relapsing-Remitting Multiple Sclerosis (TRANSFORMS), a phase 3 study of fingolimod in multiple sclerosis
-
Barkhof F, de Jong R, Sfikas N, et al. The influence of patient demographics, disease characteristics and treatment on brain volume loss in Trial Assessing Injectable Interferon vs FTY720 Oral in Relapsing-Remitting Multiple Sclerosis (TRANSFORMS), a phase 3 study of fingolimod in multiple sclerosis. Mult Scler 2014;20:1704-1713
-
(2014)
Mult Scler
, vol.20
, pp. 1704-1713
-
-
Barkhof, F.1
De Jong, R.2
Sfikas, N.3
-
24
-
-
0036161001
-
Brain atrophy in clinically early relapsing-remitting multiple sclerosis
-
Chard DT, Griffin CM, Parker GJ, Kapoor R, Thompson AJ, Miller DH. Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain 2002; 125:327-337
-
(2002)
Brain
, vol.125
, pp. 327-337
-
-
Chard, D.T.1
Griffin, C.M.2
Parker, G.J.3
Kapoor, R.4
Thompson, A.J.5
Miller, D.H.6
-
25
-
-
84860389100
-
Grey matter volume in a large cohort of MS patients: Relation to MRI parameters and disability
-
Roosendaal SD, Bendfeldt K, Vrenken H, et al. Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability. Mult Scler 2011;17:1098-1106
-
(2011)
Mult Scler
, vol.17
, pp. 1098-1106
-
-
Roosendaal, S.D.1
Bendfeldt, K.2
Vrenken, H.3
-
26
-
-
20444385866
-
The relationship between whole brain volume and disability in multiple sclerosis: A comparison of normalized gray vs. White matter with misclassification correction
-
Sanfilipo MP, Benedict RH, Sharma J, Weinstock-Guttman B, Bakshi R. The relationship between whole brain volume and disability in multiple sclerosis: a comparison of normalized gray vs. white matter with misclassification correction. Neuroimage 2005;26:1068-1077
-
(2005)
Neuroimage
, vol.26
, pp. 1068-1077
-
-
Sanfilipo, M.P.1
Benedict, R.H.2
Sharma, J.3
Weinstock-Guttman, B.4
Bakshi, R.5
-
27
-
-
0037426402
-
Evidence of early cortical atrophy in MS: Relevance to white matter changes and disability
-
De Stefano N, Matthews PM, Filippi M, et al. Evidence of early cortical atrophy in MS: relevance to white matter changes and disability. Neurology 2003;60:1157-1162
-
(2003)
Neurology
, vol.60
, pp. 1157-1162
-
-
De Stefano, N.1
Matthews, P.M.2
Filippi, M.3
-
28
-
-
10944230117
-
The relationship between inflammation and atrophy in clinically isolated syndromes suggestive of multiple sclerosis: A monthly MRI study after triple-dose gadolinium-DTPA
-
Paolillo A, Piattella MC, Pantano P, et al. The relationship between inflammation and atrophy in clinically isolated syndromes suggestive of multiple sclerosis: a monthly MRI study after triple-dose gadolinium-DTPA. J Neurol 2004;251:432-439
-
(2004)
J Neurol
, vol.251
, pp. 432-439
-
-
Paolillo, A.1
Piattella, M.C.2
Pantano, P.3
-
30
-
-
84855452907
-
Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI
-
Kitzler HH, Su J, Zeineh M, et al. Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI. Neuroimage 2012; 59:2670-2677
-
(2012)
Neuroimage
, vol.59
, pp. 2670-2677
-
-
Kitzler, H.H.1
Su, J.2
Zeineh, M.3
-
31
-
-
67349255354
-
Gray matter atrophy correlates with MS disability progression measured with MSFC but not EDSS
-
Rudick RA, Lee JC, Nakamura K, Fisher E. Gray matter atrophy correlates with MS disability progression measured with MSFC but not EDSS. J Neurol Sci 2009;282: 106-111
-
(2009)
J Neurol Sci
, vol.282
, pp. 106-111
-
-
Rudick, R.A.1
Lee, J.C.2
Nakamura, K.3
Fisher, E.4
-
32
-
-
33644887189
-
Disability progression in multiple sclerosis is slower than previously reported
-
Tremlett H, Paty D, Devonshire V. Disability progression in multiple sclerosis is slower than previously reported. Neurology 2006;66:172-177
-
(2006)
Neurology
, vol.66
, pp. 172-177
-
-
Tremlett, H.1
Paty, D.2
Devonshire, V.3
-
33
-
-
84896835232
-
Clinical relevance of brain volume measures in multiple sclerosis
-
De Stefano N, Airas L, Grigoriadis N, et al. Clinical relevance of brain volume measures in multiple sclerosis. CNS Drugs 2014;28:147-156.
-
(2014)
CNS Drugs
, vol.28
, pp. 147-156
-
-
De Stefano, N.1
Airas, L.2
Grigoriadis, N.3
|