Inhibitory effects of kaempferol-3-O-rhamnoside on ovalbumin-induced lung inflammation in a mouse model of allergic asthma

International Immunopharmacology

Volumn 25, Issue 2, 2015, Pages 302-310

  Chung, Mi Ja ^a   Pandey, Ramesh Prasad ^b   Choi, Ji Won ^c   Sohng, Jae Kyung ^b   Choi, Doo Jin ^c   Park, Yong Il ^c  

^a Kwangju University   (South Korea)

^b SunMoon University   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Anti asthma; Anti inflammatory; Glycosylation; Kaempferol; Kaempferol 3 O rhamnoside

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; KAEMPFEROL; KAEMPFEROL 3 O RHAMNOSIDE; KAEMPFEROL DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ALLERGEN; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; CYTOKINE; GLYCOSIDE; KAEMPFEROL 3-O-RHAMNOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; OVALBUMIN;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL COUNT; CONTROLLED STUDY; EOSINOPHILIA; FEMALE; HISTOPATHOLOGY; INFLAMMATORY CELL; LUNG LAVAGE; MOUSE; NONHUMAN; OVALBUMIN-INDUCED AIRWAY INFLAMMATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; BLOOD; BRONCHOALVEOLAR LAVAGE FLUID; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY;

ALANINE TRANSAMINASE; ALLERGENS; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASPARTATE AMINOTRANSFERASES; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GLYCOSIDES; IMMUNOGLOBULIN E; KAEMPFEROLS; LUNG; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; OVALBUMIN; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES;

EID: 84923628333     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.01.031     Document Type: Article

References (27)

1. M.J. Chung, J.W. Park, and Y.I. Park Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice Int Immunopharmacol 12 2012 453 459
2. N. Berend, C.M. Salome, and G.G. King Mechanisms of airway hyperresponsivess in asthma Respirology 13 2008 624 631
3. D.W. Cockcroft, and B.E. Davis Mechanisms of airway hyperresponsiveness J Allergy Clin Immunol 118 2006 551 559
4. J.H. Gong, D.K. Shin, S.Y. Han, J.L. Kim, and Y.H. Kang Kaempferol suppresses eosinophil infiltration and airway inflammation in airway epithelial cells and in mice with allergic asthma J Nutr 142 2012 47 56
5. F.Y. Goh, N. Upton, S. Guan, C. Cheng, M.K. Shanmugam, and G. Sethi Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-kB Eur J Pharmacol 679 2012 109 116
6. J.J. Kim, H.W. Cho, H.R. Park, U. Jung, S.K. Jo, and S.T. Yee Preventative effect of an herbal preparation (HemoHIM) on development of airway inflammation in mice via modulation of Th1/2 cells differentiation PLoS One 2013 e68552
7. M.J. Chung, J.K. Sohng, D.J. Choi, and Y.I. Park Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells Life Sci 93 2013 401 408
8. J.P. Spencer Flavonoids: modulators of brain function? Br J Nutr 99 E Suppl 1 2008 ES60 ES77
9. W.W. Huang, Y.J. Chiu, M.J. Fan, H.F. Lu, H.F. Yeh, and K.H. Li Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells Mol Nutr Food Res 54 2010 1585 1595
10. M.Y. Mahat, N.M. Kulkarni, S.L. Vishwakarma, F.R. Khan, B.S. Thippeswamy, and V. Hebballi Modulation of the cyclooxygenase pathway via inhibition of nitric oxide production contributes to the anti-inflammatory activity of kaempferol Eur J Pharmacol 642 2010 169 176
11. M.J. Chung, A.Y. Kang, K.M. Lee, E.J. Oh, H.J. Jun, and S.Y. Kim Water-soluble genistin glycoside isoflavones up-regulate antioxidant metallothionein expression and scavenge free radicals J Agric Food Chem 54 2006 3819 3826
12. D. Bowles, E.K. Lim, B. Poppenberger, and F.E. Vaistij Glycosyltransferases of lipophilic small molecules Annu Rev Plant Biol 57 2006 567 597
13. V. Kren, and L. Martinkova Glycosides in medicine: the role of glycosidic residue in biological activity Curr Med Chem 8 2001 1303 1328
14. A.C. Weymouth-Wilson The role of carbohydrates in biologically active natural products Nat Prod Rep 14 1997 99 110
15. M.G. Sharoar, A. Thapa, M. Shahnawaz, V.S. Ramasamy, E.R. Woo, and S.Y. Shin Kaempferol-3-O-rhamnoside abrogates amyloid beta toxicity by modulating monomers and remodeling oligomers and fibrils to non-toxic aggregates J Biomed Sci 19 2012 104
16. A. Diantini, A. Subarnas, K. Lestari, E. Halimah, Y. Susilawati, and S. Supriyatna Kaempferol-3-O-rhamnoside isolated from the leaves of Schima wallichii Korth. inhibits MCF-7 breast cancer cell proliferation through activation of the caspase cascade pathway Oncol Lett 3 2012 1069 1072
17. D. Simkhada, H.C. Lee, and J.K. Sohng Genetic engineering approach for the production of rhamnosyl and allosyl flavonoids from Escherichia coli Biotechnol Bioeng 107 2010 154 162
18. L.V. Altman, G.H. Ayars, C. Baker, and D.L. Luchtel Cytokines and eosinophil-derived cationic proteins upregulate intercellular cell adhesion molecule-1 on human nasal epithelial cells J Allergy Clin Immunol 92 1993 527 536
19. M.Y. Lee, C.S. Seo, J.A. Lee, N.H. Lee, J.H. Kim, and H.K. Ha Anti-asthmatic effects of Angelica dahurica against ovalbumin-induced airway inflammation via upregulation of heme oxygenase-1 Food Chem Toxicol 49 2011 829 837
20. H. Hortensia Moreno-Macias, and I. Romieu Effects of antioxidant supplements and nutrients on patients with asthma and allergies J Allergy Clin Immunol 133 2014 1237 1244
21. R.P. Bowler, and J.D. Crapo Oxidative stress in allergic respiratory diseases J Allergy Clin Immunol 110 2002 349 356
22. Y. Bellik, L. Boukraâ, H.A. Alzahrani, B.A. Bakhotmah, F. Abdellah, and S.M. Hammoudi Molecular mechanism underlying anti-inflammatory and anti-allergic activities of phytochemicals Molecules 18 2013 322 353
23. Y.Z. Cai, M. Sun, J. Xing, Q. Luo, and H. Corke Structure-radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants Life Sci 25 2006 2872 2888
24. L.C. Hazlewood, L.G. Wood, P.M. Hansbro, and P.S. Foster Dietary lycopene supplementation suppresses Th2 responses and lung eosinophilia in a mouse model of allergic asthma J Nutr Biochem 22 2011 95 100
25. L. Wang, S. Gao, W. Xua, S. Zhao, J. Zhoua, and N. Wangd Allergic asthma accelerates atherosclerosis dependent on Th2 and Th17 in apolipoprotein E deficient mice J Mol Cell Cardiol 72 2014 20 27
26. S. Korn, I. Haasler, F. Fliedner, G. Becher, P. Strohner, and A. Staatz Monitoring free serum IgE in severe asthma patients treated with omalizumab Respir. Med. 106 2012 1494 1500
27. A. Diantini, A. Subarnas, K. Lestar, E. Halimah, Y. Susilawati, and Julaeha E. Supriyatna Kaempferol-3-O-rhamnoside isolated from the leaves of Schima wallichii Korth. inhibit MCF-7 breast cancer cell proliferation through activation of the caspase cascade pathway Oncol Lett 3 2012 1069 1072