Th17 inflammation model of oropharyngeal candidiasis in immunodeficient mice

Journal of Visualized Experiments

Volumn , Issue 96, 2015, Pages

  Bhaskaran, Natarajan ^a   Weinberg, Aaron ^a   Pandiyan, Pushpa ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Candida; Issue 96; Medicine; Mouse model; Oral infection and immunopathology; Oral inflammation; Treg; Th17

Indexed keywords

ADOPTIVE TRANSFER; ANIMAL; CANDIDA ALBICANS; CANDIDIASIS, ORAL; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; INFLAMMATION; MOUSE; PATHOLOGY; PROCEDURES; TH17 CELL; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; CANDIDA ALBICANS; CANDIDIASIS, ORAL; IMMUNOCOMPROMISED HOST; INFLAMMATION; MICE; MICE, TRANSGENIC; TH17 CELLS;

EID: 84923596902     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/52538     Document Type: Article

References (31)

1. Allam, J. P., et al. IL-23-producing CD68(+) macrophage-like cells predominate within an IL-17-polarized infiltrate in chronic periodontitis lesions. Journal of Clinical Periodontology. 38, (10), 879-886 (2011).
2. Loesche, W. J. Periodontal disease: link to cardiovascular disease. Compendium Of Continuing Education In Dentistry. 21, (6), 463-466 (2000).
3. Sfyroeras, G. S., Roussas, N., Saleptsis, V. G., Argyriou, C., Giannoukas, A. D. Association between periodontal disease and stroke. Journal Of Vascular Surgery. 55, (4), 1178-1184 (2012).
4. Huppler, A. R., Bishu, S., Gaffen, S. L. Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy. Arthritis Research & Therapy. 14, (4), 217 (2012).
5. Sitheeque, M. A., Samaranayake, L. P. Chronic hyperplastic candidosis/candidiasis (candidal leukoplakia). Critical Reviews In. Oral Biology And Medicine : An Official Publication Of The American Association Of Oral Biologists. 14, (4), 253-267 (2003).
6. Canabarro, A., et al. Association of subgingival colonization of Candida albicans and other yeasts with severity of chronic periodontitis. Journal Of Periodontal Research. 48, (4), 428-432 (2013).
7. Urzua, B., et al. Yeast diversity in the oral microbiota of subjects with periodontitis: Candida albicans and Candida dubliniensis colonize the periodontal pockets. Medical Mycology. 46, (8), 783-793 (2008).
8. Ergun, S., et al. Oral status and Candida colonization in patients with Sjogren's Syndrome. Medicina Oral, Patologia Oral Y Cirugia Bucal. 15, (2), e310-e315 (2010).
9. Hernandez, Y. L., Daniels, T. E. Oral candidiasis in Sjogren's syndrome: prevalence, clinical correlations, and treatment. Oral Surgery, Oral Medicine, And Oral Pathology. 68, (3), 324-329 (1989).
10. Gall, F., et al. Candida spp. in oral cancer and oral precancerous lesions. The New Microbiologica. 36, (3), 283-288 (2013).
11. Grady, J. F., Reade, P. C. Candida albicans as a promoter of oral mucosal neoplasia. Carcinogenesis. 13, (5), 783-786 (1992).
12. Dwivedi, P. P., Mallya, S., Dongari-Bagtzoglou, A. A novel immunocompetent murine model for Candida albicans-promoted oral epithelial dysplasia. Medical Mycology. 47, (2), 157-167 (2009).
13. Cheng, S. C., Joosten, L. A., Kullberg, B. J., Netea, M. G. Interplay between Candida albicans and the mammalian innate host defense. Infection and Immunity. 80, (4), 1304-1313 (2012).
14. Marodi, L., Johnston, R. B. Invasive Candida species disease in infants and children: occurrence, risk factors, management, and innate host defense mechanisms. Current Opinion In Pediatrics. 19, (6), 693-697 (2007).
15. Kumamoto, C. A. Inflammation and gastrointestinal Candida colonization. Current Opinion In. Microbiology. 14, (4), 386-391 (2011).
16. Kraneveld, E. A., et al. The relation between oral Candida load and bacterial microbiome profiles in Dutch older adults. PloS One. 7, (8), e42770 (2012).
17. Hernandez-Santos, N., et al. Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections. Mucosal Immunology. 6, (5), 900-910 (2013).
18. Hasina, R., et al. ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis. Cancer Prevention Research. 2, (4), 385-393 (2009).
19. Pandiyan, P., et al. CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model. Immunity. 34, (3), 422-434 (2011).
20. Pandiyan, P., et al. The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes. J Immunol. 189, (9), 4237-4246 (2012).
21. Pandiyan, P., Lenardo, M. J. The control of CD4+CD25+Foxp3+ regulatory T cell survival. Biology Direct. 3, (6), (2008).
22. Pandiyan, P., Zheng, L., Ishihara, S., Reed, J., Lenardo, M. J. CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells. Nat Immunol. 8, (12), 1353-1362 (2007).
23. Conti, H. R., Huppler, A. R., Whibley, N., Gaffen, S. L., et al. Animal models for candidiasis. Current Protocols In Immunology. Coligan, J. E., et al. 105, 11-19 (2014).
24. Conti, H. R., et al. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med. 206, (2), 299-311 (2009).
25. Kamai, Y., et al. New model of oropharyngeal candidiasis in mice. Antimicrobial Agents And Chemotherapy. 45, (11), 3195-3197 (2001).
26. Pandiyan, P., Bhaskaran, N., Zhang, Y., Weinberg, A. Isolation of T cells from mouse oral tissues. Biological Procedures Online. 16, (1), 4 (2014).
27. Gladiator, A., Wangler, N., Trautwein-Weidner, K., LeibundGut-Landmann, S. Cutting edge: IL-17-secreting innate lymphoid cells are essential for host defense against fungal infection. J Immunol. 190, (2), 521-525 (2013).
28. Leppkes, M., Roulis, M., Neurath, M. F., Kollias, G., Becker, C. Pleiotropic functions of TNF-alpha in the regulation of the intestinal epithelial response to inflammation. International Immunology. 26, (9), 509-515 (2014).
29. Bishu, S., et al. The adaptor CARD9 is required for adaptive but not innate immunity to oral mucosal Candida albicans infections. Infection and Immunity. 82, (3), 1173-1180 (2014).
30. Quintin, J., et al. Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice. Eur J Immunol. 44, (8), 2405-2414 (2014).
31. Ramirez-Garcia, A., et al. Candida albicans and cancer: Can this yeast induce cancer development or progression. Critical Reviews In Microbiology. 1-13 (2014).