Relationship Between Blood Lead Levels and Hematological Indices in Pregnant Women

Women and Health

Volumn 55, Issue 1, 2015, Pages 90-102

  La Llave León, Osmel ^a   Lugo Soto, Rodrigo ^b   Aguilar Durán, Marisela ^a   Estrada Martínez, Sergio ^a   Salas Pacheco, José Manuel ^a   Sandoval Carrillo, Ada ^a   Castellanos Juárez, Francisco Xavier ^a   Barraza Salas, Marcel ^a   Vázquez Alanís, Fernando ^c   García Vargas, Gonzalo ^a  

^a UNIVERSIDAD JUÁREZ DEL ESTADO DE DURANGO   (Mexico)

^b Hospital de El Salto Secretaría de Salud de Durango   (Mexico)

^c Hospital General de Durango   (Mexico)

Author keywords

blood lead; pregnancy; pregnancy hematological indices

Indexed keywords

HEMOGLOBIN; LEAD;

ADOLESCENT; ADULT; BLOOD; CHEMISTRY; ERYTHROCYTE; FEMALE; HEMATOCRIT; HUMAN; MEAN CORPUSCULAR VOLUME; PHYSIOLOGY; PREGNANCY; YOUNG ADULT;

ADOLESCENT; ADULT; ERYTHROCYTE INDICES; ERYTHROCYTES; FEMALE; HEMATOCRIT; HEMOGLOBINS; HUMANS; LEAD; PREGNANCY; PREGNANCY TRIMESTERS; YOUNG ADULT;

EID: 84923593545     PISSN: 03630242     EISSN: 15410331     Source Type: Journal    
DOI: 10.1080/03630242.2014.972019     Document Type: Article

References (37)

1. Ahamed, M., S. Singh, J. R. Behari, A. Kumar, and M. K. J. Siddiqui. 2007. Interaction of lead with some essential trace metals in the blood of anemic children from Lucknow, India. Clin Chim Acta 377:92–7. doi:10.1016/j.cca.2006.08.032
2. Anetor, J. I., T. S. Akingbola, F. A. A. Adeniyi, and G. A. L. Taylor. 2005. Decreased total and ionized calcium levels and haematological indices in occupational lead exposure as evidence of the endocrine disruptive effect of lead. Indian J Occu Env Med 9:15–21. doi:10.4103/0019-5278.16036
3. Borja-Aburto, V. H., I. Hertz-Picciotto, M. Rojas-Lopez, P. Farias, C. Rios, and J. Blanco. 1999. Blood lead levels measured prospectively and risk of spontaneous abortion. Am J Epidemiol 150:590–7. doi:10.1093/oxfordjournals.aje.a010057
4. EPA (Environmental Protection Agency). 2004. Hazard identification. Washington, DC. http://www.epa.gov/lead/rach2.pdf (accessed June 19, 2013).
5. Feng, J., B. A. Witthuhn, T. Matsuda, F. Kohlhuber, I. M. Kerr, and J. N. Ihle. 1997. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop. Mol Cell Biol 17(5):2497–501.
6. Fernández, C., J. Sergio, and J. Sordo. 2006. An overview of the historical importance, occurrence, isolation, properties and applications of lead. In Lead: Chemistry, analytical aspects, environmental impact and health effects, ed. J. S. Casas and J. Sordo, 1–40. Galicia, Spain: Universidad de Santiago de Compostela.
7. Fontana, V., R. Baldi, M. Franchini, P. Gridelli, R. Neri, F. Palmieri, 2004. Adverse haematological outcome and environmental lead poisoning. J Expos Anal Env Epidemiol 14:188–93. doi:10.1038/sj.jea.7500318
8. Froom, P., E. Kristal-Boneh, J. Benbassat, R. Ashkanazi, and J. Ribak. 1999. Lead exposure in battery-factory workers is not associated with anemia. J Occu Env Med 41:120–3. doi:10.1097/00043764-199902000-00007
9. Guerra-Tamayo, J. L., L. Hernández-Cadena, M. Téllez-Rojo, A. Mercado-García, M. Solano-González, M. Hernández-Avila, and H. Hu. 2003. Exposición al plomo y su relación con el tiempo requerido para embarazo. Salud Pública de México 45:189–95. doi:10.1590/S0036-36342003000800004
10. Hegazy, A., M. Zaher, M. Abd El-Hafez, A. Morsy, and R. Saleh. 2010. Relation between anemia and blood levels of lead, copper, zinc and iron among children. BMC Res Notes 3:133. doi:10.1186/1756-0500-3-133
11. Hipkins, K. L., and M. J. Kosnett. 2006. Lead poisoning. In Occupational medicine secrets, ed. R. Bowlerand and J. Cone, 60–70. Philadelphia, PA: Hanley & Belfus.
12. Horsawad, V., P. Pongpaew, R. Tungtrongchitr, B. Phonrat, N. Vudhivai, S. Chanjanakitskul, 1999. Lead exposure, urinary delta-aminolevulinic acid concentrations and haematological parameters of road sweepers working in congested areas of Bangkok. Jf Nutr Env Med 9:109–14. doi:10.1080/13590849961708
13. Hu, H., M. M. Téllez-Rojo, D. Bellinger, D. Smith, A. S. Ettinger, H. Lamadrid-Figueroa, 2006. Fetal lead exposure at each stage of pregnancy as a predictor of infant mental development. Env Health Perspec 114:1730–5.
14. Jacob, B., B. Ritz, J. Heinrich, B. Hoelscher, and H.-E. Wichmann. 2000. The effect of low-level blood lead on hematologic parameters in children. Env Res 82:150–9. doi:10.1006/enrs.1999.4011
15. Jain, N. B., F. Laden, U. Guller, A. Shankar, S. Kazani, and E. Garshick. 2005. Relation between blood lead levels and childhood anemia in India. Am J Epidemiol 161:968–73. doi:10.1093/aje/kwi126
16. Jusko, T. A., C. R. Henderson, B. Lanphear, D. Cory-Slechta, P. Parsons, and R. Candfield. 2008. Blood lead concentrations < 10 μg/dL and child intelligence at 6 years of age. Env Health Perspec 116:243–8.
17. Karita, K., E. Yano, M. Dakeishi, T. Iwata, and K. Murata. 2005. Benchmark dose of lead inducing anemia at the workplace. Risk Anal 25:957–62. doi:10.1111/j.1539-6924.2005.00652.x
18. Keramati, M. R., M. H. Sadeghian, and M. Mood. 2010. Correlation between iron deficiency and lead intoxication in the workers of a car battery plant. Int J Hematol Oncol 3:169–75.
19. Kianoush, S., M. Balali-Mood, S. R. Mousavi, M. T. Shakeri, B. Dadpour, V. Moradi, and M. Sadeghi. 2013. Clinical, toxicological, biochemical, and hematologic parameters in lead exposed workers of a car battery industry. Iran J Med Sci 38(1):30–7.
20. Kim, H.-S., S.-S. Lee, Y. Hwangbo, K.-D. Ahn, and B.-K. Lee. 2003. Cross-sectional study of blood lead effects on iron status in Korean lead workers. Nutrition 19:571–6. doi:10.1016/S0899-9007(03)00035-2
21. Kordas, K., P. Lopez, J. L. Rosado, G. García-Vargas, J. Alatorre, D. Ronquillo, 2004. Blood lead, anemia, and short stature are independently associated with cognitive performance in Mexican school children. J Nutr 134:363–71.
22. Kosnett, M. J., R. P. Wedeen, S. J. Rothenberg, K. L. Hipkins, B. L. Materna, B. S. Schwartz, 2007. Recommendations for medical management of adult lead exposure. Env Health Perspec 115:463–71. doi:10.1289/ehp.9784
23. La-Llave-León, O., S. Estrada-Martínez, J. M. Salas-Pacheco, R. Peña-Elósegui, J. Duarte-Sustaita, J.-L. Candelas-Rangel, and G. García Vargas. 2011. Blood lead levels and risk factors in pregnant women from Durango, Mexico. Arch Env Occu Health 66(2):107–13. doi:10.1080/19338244.2010.511311
24. Lanphear, B. P., R. Hornung, M. Ho, C. R. Howard, S. Eberly, and K. Knauf. 2002. Environmental lead exposure during early childhood. J Pediatr 140:40–7. doi:10.1067/mpd.2002.120513
25. Latorre, F. G., M. Hernández-Avila, J. T. Orozco, C. A. A. Medina, A. Aro, E. Palazuelos, and H. Hu. 2003. Relationship of blood and bone lead to menopause and bone mineral density among middle-age women in Mexico City. Env Health Perspec 111:631–6. doi:10.1289/ehp.5149
26. Minkina, T. M. 2010. Heavy metal compound in soil. Transformation upon soil pollution and ecological significance. New York, NY: Nova Science.
27. Mostafa, G. A., H. H. El-Shahawi, and A. Mokhtar. 2009. Blood lead levels in Egyptian children from high and low lead-polluted areas: Impact on cognitive function. Acta Neur Scandinavica 120:30–7. doi:10.1111/j.1600-0404.2009.01155.x
28. Queirolo, E., A. Ettinger, R. Stoltzfus, and K. Kordas. 2010. Association of anemia, child and family characteristics with elevated blood lead concentrations in preschool children from Montevideo, Uruguay. Arch Env Occu Health 65:94–100. doi:10.1080/19338240903390313
29. Rahman, A., B. J. Brew, and G. J. Guillemin. 2011. Lead dysregulates serine/threonine protein phosphatases in human neurons. Neurochem Res 36(2):195–204. doi:10.1007/s11064-010-0300-6
30. Rogival, D., J. Scheirs, W. De Coen, R. Verhagen, and R. Blust. 2006. Metal blood levels and hematological characteristics in wood mice (Apodemus Sylvaticus L.) along a metal pollution gradient. Env Toxicol Chem 25:149. doi:10.1897/04-659R1.1
31. Sanborn, M. D., D. Cole, A. Abelsohn, M. Camppbell, and E. Weir. 2002. Identifying and managing adverse environmental health effects: 3. Lead exposure. Can Med Assoc J 166(10):1287–92.
32. Shah, F., T. Kazi, H. Afridi, J. Baig, S. Khan, N. Kolachi, 2010. Environmental exposure of lead and iron deficit anemia in children age ranged 1–5 years: A cross sectional study. Sci Total Env 408:5325–30. doi:10.1016/j.scitotenv.2010.07.091
33. Stoleski, S., J. Karadzinska-Bilimovska, E. Stikova, S. Risteska-Kuc, D. Mijakoski, and J. Minov. 2008. Adverse effect in workers exposed to inorganic lead. Arch Ind Hygiene Toxicol 59:19–29.
34. Tozun, M., A. Unzal, and B. Sirmagul. 2009. The lead exposure among lead workers: An epidemiological study from West Turkey. Iran J Publ Health 38:65–78.
35. Vigeh, M., K. Yokoyama, M. Mazaheri, S. Beheshti, S. Ghazizadeh, T. Sakai, 2004. Relationship between increased blood lead and pregnancy hypertension in women without occupational lead exposure in Tehran, Iran. Arch Env Health 59:70–5. doi:10.3200/AEOH.59.2.70-75
36. Yánez, C., M. L. Di Bernardo, M. Y. García, N. Ríos, J. Rincón, N. Rodríguez, 2008. Assessment of some hematological and biochemical parameters as biomarkers of occupational exposure to lead, in Mérida, Venezuela. Retel 14:13–23.
37. Yazbeck, C., O. Thiebaugeorges, T. Moreau, V. Goua, G. Debotte, J. Sahuquillo, 2009. Maternal blood lead levels and the risk of pregnancy-induced hypertension: The EDEN cohort study. Env Health Perspec 117:1526–30. doi:10.1289/ehp.0800488