Clinical, toxicological, biochemical, and hematologic parameters in lead exposed workers of a car battery industry

Iranian Journal of Medical Sciences

Volumn 38, Issue 1, 2013, Pages 30-37

  Kianoush, Sina ^a   Balali Mood, Mahdi ^a   Mousavi, Seyed Reza ^a   Shakeri, Mohammad Taghi ^b   Dadpour, Bita ^a   Moradi, Valiollah ^a   Sadeghi, Mahmoud ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Biochemical markers; Hematologic tests; Lead poisoning; Occupational exposure

Indexed keywords

CHOLESTEROL; CREATININE; GLUCOSE; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN; LEAD; LOW DENSITY LIPOPROTEIN; NITROGEN; TRIACYLGLYCEROL; UREA; URIC ACID;

ABDOMINAL PAIN; ABDOMINAL TENDERNESS; ADULT; AGITATION; ANHEDONIA; ANOREXIA; ARTHRALGIA; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BATTERY INDUSTRY; BREATHING RATE; CHOLESTEROL BLOOD LEVEL; CONCENTRATION LOSS; CONJUNCTIVA DISEASE; CREATININE BLOOD LEVEL; DENTAL CARIES; ERYTHROCYTE COUNT; EXCITABILITY; FATIGUE; GLUCOSE BLOOD LEVEL; HAND PARESTHESIA; HEADACHE; HEART RATE; HEMATOCRIT; HUMAN; HYPERREFLEXIA; HYPERTENSION; HYPOREFLEXIA; INDUSTRIAL WORKER; INSOMNIA; LEAD BLOOD LEVEL; LEAD POISONING; LIBIDO DISORDER; LIMB WEAKNESS; LIPOPROTEIN BLOOD LEVEL; LONG TERM EXPOSURE; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALAISE; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEMORY DISORDER; MOOD DISORDER; MUSCLE ATROPHY; MYALGIA; NAUSEA; NEUTROPHIL COUNT; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL HEALTH; QUESTIONNAIRE; SOMNOLENCE; TOOTH DISCOLORATION; TOXICITY TESTING; TREMOR; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL; URINALYSIS; VISUAL IMPAIRMENT;

EID: 84875536203     PISSN: 02530716     EISSN: 17353688     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Staudinger KC, Roth VS. Occupational lead poisoning. Am Fam Physician. 1998;57:719-26. PubMed PMID: 9490995.
2. Hettmansberger TL, Mycyk MB. Lead poisoning presents a difficult diagnosis. Am Fam Physician. 2002;66:1839-40. PubMed PMID: 12469959.
3. Centers for Disease Control and Prevention (CDC). Adult blood lead epidemiology and surveillance--United States, 2002. MMWR Morb Mortal Wkly Rep. 2004;53:578-82. PubMed PMID: 15241299.
4. Hernberg S. Lead poisoning in a historical perspective. Am J Ind Med. 2000;38:244-54. doi: 10.1002/1097-0274(200009)38:3<244::AID-AJIM3>3.0.CO;2-F. PubMed PMID: 10940962.
5. Bellinger DC. Lead. Pediatrics. 2004;113:1016-22. PubMed PMID: 15060194.
6. Patrick L. Lead toxicity, a review of the literature. Part 1: Exposure, evaluation, and treatment. Altern Med Rev. 2006;11:2-22. PubMed PMID: 16597190.
7. Kosnett MJ, Wedeen RP, Rothenberg SJ, Hipkins KL, Materna BL, Schwartz BS, et al. Recommendations for medical management of adult lead exposure. Environ Health Perspect. 2007;115:463-71. doi: 10.1289/ehp.9784. PubMed PMID: 17431500; PubMed Central PMCID: PMC1849937.
8. Pearce JM. Burton's line in lead poisoning. Eur Neurol. 2007;57:118-9. doi: 10.1159/000098100. PubMed PMID: 17179719.
9. Malekirad AA, Oryan S, Fani A, Babapor V, Hashemi M, Baeeri M, et al. Study on clinical and biochemical toxicity biomarkers in a zinc-lead mine workers. Toxicol Ind Health. 2010;26:331-7. doi: 10.1177/0748233710365697. PubMed PMID: 20371635.
10. Marcus AH. Multicompartment kinetic model for lead. III. Lead in blood plasma and erythrocytes. Environ Res. 1985;36:473-89. PubMed PMID: 3979365.
11. Macklin R. The Declaration of Helsinki: another revision. Indian J Med Ethics. 2009;6:2-4. PubMed PMID: 19241946.
12. Karimooy HN, Mood MB, Hosseini M, Shadmanfar S. Effects of occupational lead exposure on renal and nervous system of workers of traditional tile factories in Mashhad (northeast of Iran). Toxicol Ind Health. 2010;26:633-8. doi: 10.1177/0748233710377774. PubMed PMID: 20630982.
13. Balali-Mood M, Shademanfar S, Rastegar Moghadam J, Afshari R, Namaei Ghassemi M, Allah Nemati H, et al. Occupational lead poisoning in workers of traditional tile factories in Mashhad, Northeast of Iran. Int J Occup Environ Med. 2010;1:29-38. PubMed PMID: 23022779.
14. Porru S, Alessio L. The use of chelating agents in occupational lead poisoning. Occup Med (Lond). 1996;46:41-8. doi: 10.1093/occmed/46.1.41. PubMed PMID: 8672793
15. Baker EL Jr, Landrigan PJ, Barbour AG, Cox DH, Folland DS, Ligo RN, et al. Occupational lead poisoning in the United States: clinical and biochemical findings related to blood lead levels. Br J Ind Med. 1979;36:314-22. doi: 10.1136/oem.36.4.314. PubMed PMID: 508643.
16. Weisser B, Mengden T, Düsing R, Vetter H, Vetter W. Normal values of blood pressure self-measurement in view of the 1999 World Health Organization-International Society of Hypertension guidelines. Am J Hypertens. 2000;13:940-3. doi: 10.1016/S0895-7061(00)00259-4. PubMed PMID: 10950404.
17. Wirtz A, Lombardi DA, Willetts JL, Folkard S, Christiani DC. Gender differences in the effect of weekly working hours on occupational injury risk in the United States working population. Scand J Work Environ Health. 2012;38:349-57. doi: 10.5271/sjweh.3295. PubMed PMID: 22466526.
18. Nolan CV, Shaikh ZA. Lead nephrotoxicity and associated disorders: biochemical mechanisms. Toxicology. 1992;73:127-46. doi: 10.1016/0300-483X(92)90097-X. PubMed PMID: 1319092.
19. Den Hond E, Nawrot T, Staessen JA. The relationship between blood pressure and blood lead in NHANES III. National Health and Nutritional Examination Survey. J Hum Hypertens. 2002;16:563-8. PubMed PMID: 12149662.
20. Dolenc P, Staessen JA, Lauwerys RR, Amery A. Short report: low-level lead exposure does not increase the blood pressure in the general population. Cadmibel Study Group. J Hypertens. 1993;11:589-93. PubMed PMID: 8390532.
21. Thanapop C, Geater AF, Robson MG, Phakthongsuk P, Viroonudomphol D. Exposure to lead of boatyard workers in southern Thailand. J Occup Health. 2007;49:345-52. doi: 10.1539/joh.49.345. PubMed PMID: 17951965.
22. Lanphear BP, Byrd RS, Auinger P, Schaffer SJ. Community characteristics associated with elevated blood lead levels in children. Pediatrics. 1998;101:264-71. doi: 10.1542/ peds.101.2.264. PubMed PMID: 9445502.
23. Albalak R, Noonan G, Buchanan S, Flanders WD, Gotway-Crawford C, Kim D, et al. Blood lead levels and risk factors for lead poisoning among children in Jakarta, Indonesia. Sci Total Environ. 2003;301:75-85. doi: 10.1016/ S0048-9697(02)00297-8. PubMed PMID: 12493187.
24. Gulson BL, Cameron MA, Smith AJ, Mizon KJ, Korsch MJ, Vimpani G, et al. Blood lead-urine lead relationships in adults and children. Environ Res. 1998;78:152-60. doi: 10.1006/ enrs.1997.3810. PubMed PMID: 9719619
25. Crinnion WJ. The benefits of pre-and post-challenge urine heavy metal testing: Part 1. Altern Med Rev. 2009;14:3-8. PubMed PMID: 19364190.
26. Adekunle IM, Ogundele JA, Oguntoke O, Akinloye OA. Assessment of blood and urine lead levels of some pregnant women residing in Lagos, Nigeria. Environ Monit Assess. 2010;170:467-74. doi: 10.1007/s10661-009-1247-4. PubMed PMID: 19915952.
27. Moreira Mde F, Neves EB. [Use of urine lead level as an exposure indicator and its relationship to blood lead]. Cad Saude Publica. 2008;24:2151-9. PubMed PMID: 18813691. Portuguese.
28. Katavolos P, Staempfli S, Sears W, Gancz AY, Smith DA, Bienzle D. The effect of lead poisoning on hematologic and biochemical values in trumpeter swans and Canada geese. Vet Clin Pathol. 2007;36:341-7. doi: 10.1111/j.1939-165X.2007.tb00438.x. PubMed PMID: 18041699.
29. Shah SL. Hematological parameters in tench Tinca tinca after short term exposure to lead. J Appl Toxicol. 2006;26:223-8. PubMed PMID: 16389660.
30. Shah SL, Altindag A. Hematological parameters of tench (Tinca tinca L.) after acute and chronic exposure to lethal and sublethal mercury treatments. Bull Environ Contam Toxicol. 2004;73:911-8. doi: 10.1007/s00128-004-0513-y. PubMed PMID: 15669737.
31. Akinloye O, Ogunleye K, Oguntibeju OO. Cadmium, lead, arsenic and selenium levels in patients with type 2 diabetes mellitus. Afr J Biotechnol. 2010;9:5189-95.
32. March GL, John TM, McKeown BA, Seleo L, George JC. The effects of lead poisoning on various plasma constituents in the Canada goose. J Wildl Dis. 1976;12:14-9. PubMed PMID: 1255908.
33. Alasia DD, Emem-Chioma PC, Wokoma FS. Occupational and environmental lead exposure in Port Harcourt, Nigeria: analysis of its association with renal function indices. Niger J Med. 2010;19:407-14. doi: 10.4314/ njm.v19i4.61965. PubMed PMID: 21526629.
34. Roshan VD, Assali M, Moghaddam AH, Hosseinzadeh M, Myers J. Exercise training and antioxidants: effects on rat heart tissue exposed to lead acetate. Int J Toxicol. 2011;30:190-6. doi: 10.1177/1091581810392809. PubMed PMID: 21378372.
35. Ademuyiwa O, Ugbaja RN, Idumebor F, Adebawo O. Plasma lipid profiles and risk of cardiovascular disease in occupational lead exposure in Abeokuta, Nigeria. Lipids Health Dis. 2005;4:19. PubMed PMID: 16191200; PubMed Central PMCID: PMC1253530
36. Ito Y, Niiya Y, Kurita H, Shima S, Sarai S. Serum lipid peroxide level and blood superoxide dismutase activity in workers with occupational exposure to lead. Int Arch Occup Environ Health. 1985;56:119-27. doi: 10.1007/ BF00379383. PubMed PMID: 4055067.
37. Kasperczyk S, Birkner E, Kasperczyk A, Kasperczyk J. Lipids, lipid peroxidation and 7-ketocholesterol in workers exposed to lead. Hum Exp Toxicol. 2005;24:287-95. doi: 10.1191/0960327105ht528oa. PubMed PMID: 16004195.
38. Gonick HC. Nephrotoxicity of cadmium & lead. Indian J Med Res. 2008;128:335-52. PubMed PMID: 19106433.