Identification of an association between genomic hypomethylation of fcgr2a and susceptibility to Kawasaki disease and intravenous immunoglobulin resistance by DNA methylation array

Arthritis and Rheumatology

Volumn 67, Issue 3, 2015, Pages 828-836

  Kuo, Ho Chang ^a,b   Chang, Jen Chieh ^a   Kuo, Hsing Chun ^a,b   Yu, Hong Ren ^a   Wang, Chih Lu ^c   Lee, Chiu Ping ^a   Huang, Li Tong ^a   Yang, Kuender D ^d  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c Po Jen Hospital   (Taiwan)

^d CHANG BING SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; MESSENGER RNA; FC RECEPTOR; FCGR2A PROTEIN, HUMAN;

ARTICLE; ASSAY; BREAST IMPLANT; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DNA METHYLATION; DNA SCREENING; FCGR2A GENE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOMICS; HUMAN; HUMANMETHYLATION27 BEADCHIP ASSAY; MUCOCUTANEOUS LYMPH NODE SYNDROME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PYROSEQUENCING; REPORTER GENE; VALIDATION STUDY; CHILD; CULTURE TECHNIQUE; DISEASE PREDISPOSITION; DNA MICROARRAY; DRUG RESISTANCE; FEMALE; GENETIC PREDISPOSITION; GENETICS; INFANT; MALE; PRESCHOOL CHILD; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

CELL CULTURE TECHNIQUES; CHILD; CHILD, PRESCHOOL; DISEASE SUSCEPTIBILITY; DNA METHYLATION; DRUG RESISTANCE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; INFANT; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, IGG;

EID: 84923547724     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38976     Document Type: Article

References (36)

1. Kawasaki T, Kosaki F, Okawa S, Shigematsu I, Yanagawa H,. A new infantile acute febrile mucocutaneous lymph node syndrome (MLNS) prevailing in Japan. Pediatrics 1974; 54: 271-6.
2. Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 2004; 110: 2747-71.
3. Wang CL, Wu YT, Liu CA, Kuo HC, Yang KD,. Kawasaki disease: infection, immunity and genetics. Pediatr Infect Dis J 2005; 24: 998-1004.
4. Burns JC, Glode MP,. Kawasaki syndrome. Lancet 2004; 364: 533-44.
5. Kuo HC, Liang CD, Wang CL, Yu HR, Hwang KP, Yang KD,. Serum albumin level predicts initial intravenous immunoglobulin treatment failure in Kawasaki disease. Acta Paediatr 2010; 99: 1578-83.
6. Kuo HC, Yang KD, Chang WC, Ger LP, Hsieh KS,. Kawasaki disease: an update on diagnosis and treatment. Pediatr Neonatol 2012; 53: 4-11.
7. Nakamura Y, Yashiro M, Uehara R, Sadakane A, Tsuboi S, Aoyama Y, et al. Epidemiologic features of Kawasaki disease in Japan: results of the 2009-2010 nationwide survey. J Epidemiol 2012; 22: 216-21.
8. Huang WC, Huang LM, Chang IS, Chang LY, Chiang BL, Chen PJ, et al, and the Kawasaki Disease Research Group. Epidemiologic features of Kawasaki disease in Taiwan, 2003-2006. Pediatrics 2009; 123: e401-5.
9. Park YW, Han JW, Hong YM, Ma JS, Cha SH, Kwon TC, et al. Epidemiological features of Kawasaki disease in Korea, 2006-2008. Pediatr Int 2011; 53: 36-9.
10. Onouchi Y, Onoue S, Tamari M, Wakui K, Fukushima Y, Yashiro M, et al. CD40 ligand gene and Kawasaki disease. Eur J Hum Genet 2004; 12: 1062-8.
11. Onouchi Y, Gunji T, Burns JC, Shimizu C, Newburger JW, Yashiro M, et al. ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. Nat Genet 2008; 40: 35-42.
12. Kuo HC, Yang KD, Juo SH, Liang CD, Chen WC, Wang YS, et al. ITPKC single nucleotide polymorphism associated with the Kawasaki disease in a Taiwanese population. PLoS One 2011; 6: e17370.
13. Kuo HC, Chang WC,. Genetic polymorphisms in Kawasaki disease. Acta Pharmacol Sin 2011; 32: 1193-8.
14. Kuo HC, Hsu YW, Wu CM, Chen SH, Hung KS, Chang WP, et al. A replication study for association of ITPKC and CASP3 two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease. PLoS One 2013; 8: e69685.
15. Burgner D, Davila S, Breunis WB, Ng SB, Li Y, Bonnard C, et al. A genome-wide association study identifies novel and functionally related susceptibility loci for Kawasaki disease. PLoS Genet 2009; 5: e1000319.
16. Khor CC, Davila S, Breunis WB, Lee YC, Shimizu C, Wright VJ, et al, Hong Kong-Shanghai Kawasaki Disease Genetics Consortium, Korean Kawasaki Disease Genetics Consortium, Taiwan Kawasaki Disease Genetics Consortium, International Kawasaki Disease Genetics Consortium, US Kawasaki Disease Genetics Consortium, Blue Mountains Eye Study. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet 2011; 43: 1241-6.
17. Lee YC, Kuo HC, Chang JS, Chang LY, Huang LM, Chen MR, et al. Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nat Genet 2012; 44: 522-5.
18. Onouchi Y, Ozaki K, Burns JC, Shimizu C, Terai M, Hamada H, et al, Japan Kawasaki Disease Genome Consortium, US Kawasaki Disease Genetics Consortium. A genome-wide association study identifies three new risk loci for Kawasaki disease. Nat Genet 2012; 44: 517-21.
19. Kuo HC, Yang KD, Liang CD, Bong CN, Yu HR, Wang L, et al. The relationship of eosinophilia to intravenous immunoglobulin treatment failure in Kawasaki disease. Pediatr Allergy Immunol 2007; 18: 354-9.
20. Steemers FJ, Chang W, Lee G, Barker DL, Shen R, Gunderson KL,. Whole-genome genotyping with the single-base extension assay. Nat Methods 2006; 3: 31-3.
21. Colella S, Shen L, Baggerly KA, Issa JP, Krahe R,. Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. Biotechniques 2003; 35: 146-150.
22. Chiu YW, Lin TH, Huang WS, Teng CY, Liou YS, Kuo WH, et al. Baicalein inhibits the migration and invasive properties of human hepatoma cells. Toxicol Appl Pharmacol 2011; 255: 316-26.
23. Han W, Shi M, Spivack SD,. Site-specific methylated reporter constructs for functional analysis of DNA methylation. Epigenetics 2013; 8: 1176-87.
24. Huang WS, Chin CC, Chen CN, Kuo YH, Chen TC, Yu HR, et al. Stromal cell-derived factor-1/CXC receptor 4 and β1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells. J Cell Physiol 2012; 227: 1114-22.
25. Brusov OS, Fomenko AM, Katasonov AB,. Human plasma inhibitors of platelet serotonin uptake and imipramine receptor binding: extraction and heterogeneity. Biol Psychiatry 1985; 20: 235-44.
26. Liu Y, Gao X, Masuda E, Redecha PB, Blank MC, Pricop L,. Regulated expression of FcγR in human dendritic cells controls cross-presentation of antigen-antibody complexes. J Immunol 2006; 177: 8440-7.
27. Ryu J, Lee CW, Shin JA, Park CS, Kim JJ, Park SJ, et al. FcγRIIa mediates c-reactive protein-induced inflammatory responses of human vascular smooth muscle cells by activating NADPH oxidase 4. Cardiovasc Res 2007; 75: 555-65.
28. Tan Sardjono C, Mottram PL, Hogarth PM,. The role of FcγRIIa as an inflammatory mediator in rheumatoid arthritis and systemic lupus erythematosus. Immunol Cell Biol 2003; 81: 374-81.
29. Hogarth PM,. Fc receptors are major mediators of antibody based inflammation in autoimmunity. Curr Opin Immunol 2002; 14: 798-802.
30. Van der Pol W, van de Winkel JG,. IgG receptor polymorphisms: risk factors for disease. Immunogenetics 1998; 48: 222-32.
31. Chang JC, Wang L, Chen RF, Liu CA,. Perinatal gene-gene and gene-environment interactions on igE production and asthma development. Clin Dev Immunol 2012; 2012: 270869.
32. Heard E, Disteche CM,. Dosage compensation in mammals: fine-tuning the expression of the X chromosome. Genes Dev 2006; 20: 1848-67.
33. Puck JM, Krauss CM, Puck SM, Buckley RH, Conley ME,. Prenatal test for X-linked severe combined immunodeficiency by analysis of maternal X-chromosome inactivation and linkage analysis. N Engl J Med 1990; 322: 1063-6.
34. Kuo HC, Chang WC, Yang KD, Yu HR, Wang CL, Ho SC, et al. Kawasaki disease and subsequent risk of allergic diseases: a population-based matched cohort study. BMC Pediatr 2013; 13: 38.
35. Woon PY, Chang WC, Liang CC, Hsu CH, Klahan S, Huang YH, et al. Increased risk of atopic dermatitis in preschool children with Kawasaki disease: a population-based study in Taiwan. Evid Based Complement Alternat Med 2013; 2013: 605123.
36. Bock C,. Analysing and interpreting DNA methylation data. Nat Rev Genet 2012; 13: 705-19.