메뉴 건너뛰기




Volumn 19, Issue 3, 2015, Pages 535-543

ASPP2 enhances Oxaliplatin (L-OHP)-induced colorectal cancer cell apoptosis in a p53-independent manner by inhibiting cell autophagy

Author keywords

Apoptosis; ASPP2; Autophagy; Colorectal cancer; P53

Indexed keywords

MUS;

EID: 84923448408     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12435     Document Type: Article
Times cited : (33)

References (32)
  • 1
    • 0034665461 scopus 로고    scopus 로고
    • p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage
    • Chao C, Saito S, Kang J, et al. p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage. EMBO J. 2000; 19: 4967-75.
    • (2000) EMBO J , vol.19 , pp. 4967-4975
    • Chao, C.1    Saito, S.2    Kang, J.3
  • 2
    • 0033821977 scopus 로고    scopus 로고
    • A transactivation-deficient mouse model provides insights into Trp53 regulation and function
    • Jimenez GS, Nister M, Stommel JM, et al. A transactivation-deficient mouse model provides insights into Trp53 regulation and function. Nat Genet. 2000; 26: 37-43.
    • (2000) Nat Genet , vol.26 , pp. 37-43
    • Jimenez, G.S.1    Nister, M.2    Stommel, J.M.3
  • 3
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer. 2002; 2: 594-604.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 5
    • 0024536654 scopus 로고
    • Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
    • Baker SJ, Fearon ER, Nigro JM, et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science. 1989; 244: 217-21.
    • (1989) Science , vol.244 , pp. 217-221
    • Baker, S.J.1    Fearon, E.R.2    Nigro, J.M.3
  • 6
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker SJ, Markowitz S, Fearon ER, et al. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science. 1990; 249: 912-5.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3
  • 7
    • 57049114832 scopus 로고    scopus 로고
    • The genetics of the p53 pathway, apoptosis and cancer therapy
    • Vazquez A, Bond EE, Levine AJ, et al. The genetics of the p53 pathway, apoptosis and cancer therapy. Nat Rev Drug Discov. 2008; 7: 979-87.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 979-987
    • Vazquez, A.1    Bond, E.E.2    Levine, A.J.3
  • 8
    • 0025634118 scopus 로고
    • p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis
    • Baker SJ, Preisinger AC, Jessup JM, et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 1990; 50: 7717-22.
    • (1990) Cancer Res , vol.50 , pp. 7717-7722
    • Baker, S.J.1    Preisinger, A.C.2    Jessup, J.M.3
  • 9
    • 0025761562 scopus 로고
    • p53 expression in colorectal tumors
    • Purdie CA, O'Grady J, Piris J, et al. p53 expression in colorectal tumors. Am J Pathol. 1991; 138: 807-13.
    • (1991) Am J Pathol , vol.138 , pp. 807-813
    • Purdie, C.A.1    O'Grady, J.2    Piris, J.3
  • 10
    • 33846551682 scopus 로고    scopus 로고
    • ASPP: a new family of oncogenes and tumour suppressor genes
    • Sullivan A, Lu X. ASPP: a new family of oncogenes and tumour suppressor genes. Br J Cancer. 2007; 96: 196-200.
    • (2007) Br J Cancer , vol.96 , pp. 196-200
    • Sullivan, A.1    Lu, X.2
  • 11
    • 1842854235 scopus 로고    scopus 로고
    • Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome
    • Lossos IS, Natkunam Y, Levy R, et al. Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome. Leuk Lymphoma. 2002; 43: 2309-17.
    • (2002) Leuk Lymphoma , vol.43 , pp. 2309-2317
    • Lossos, I.S.1    Natkunam, Y.2    Levy, R.3
  • 12
    • 29344451417 scopus 로고    scopus 로고
    • Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes
    • Cobleigh MA, Tabesh B, Bitterman P, et al. Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes. Clin Cancer Res. 2005; 11: 8623-31.
    • (2005) Clin Cancer Res , vol.11 , pp. 8623-8631
    • Cobleigh, M.A.1    Tabesh, B.2    Bitterman, P.3
  • 13
    • 33646578801 scopus 로고    scopus 로고
    • ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth
    • Vives V, Su J, Zhong S, et al. ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth. Genes Dev. 2006; 20: 1262-7.
    • (2006) Genes Dev , vol.20 , pp. 1262-1267
    • Vives, V.1    Su, J.2    Zhong, S.3
  • 14
    • 33645729664 scopus 로고    scopus 로고
    • The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells
    • Chen D, Yu Z, Zhu Z, et al. The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells. Cancer Res. 2006; 66: 3485-94.
    • (2006) Cancer Res , vol.66 , pp. 3485-3494
    • Chen, D.1    Yu, Z.2    Zhu, Z.3
  • 15
    • 84865191462 scopus 로고    scopus 로고
    • Autophagic activity dictates the cellular response to oncogenic RAS
    • Wang Y, Wang XD, Lapi E, et al. Autophagic activity dictates the cellular response to oncogenic RAS. Proc Natl Acad Sci U S A. 2012; 109: 13325-30.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 13325-13330
    • Wang, Y.1    Wang, X.D.2    Lapi, E.3
  • 16
    • 63149117341 scopus 로고    scopus 로고
    • Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds
    • Kampa KM, Acoba JD, Chen D, et al. Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds. Proc Natl Acad Sci U S A. 2009; 106: 4390-5.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4390-4395
    • Kampa, K.M.1    Acoba, J.D.2    Chen, D.3
  • 17
    • 79953693902 scopus 로고    scopus 로고
    • Role of p53 in Cell Death and Human Cancers
    • Ozaki T, Nakagawara A. Role of p53 in Cell Death and Human Cancers. Cancers (Basel). 2011; 3: 994-1013.
    • (2011) Cancers (Basel) , vol.3 , pp. 994-1013
    • Ozaki, T.1    Nakagawara, A.2
  • 18
    • 84874949078 scopus 로고    scopus 로고
    • ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells
    • Wang Y, Godin-Heymann N, Dan Wang X, et al. ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells. Cell Death Differ. 2013; 20: 525-34.
    • (2013) Cell Death Differ , vol.20 , pp. 525-534
    • Wang, Y.1    Godin-Heymann, N.2    Dan Wang, X.3
  • 19
    • 17944379798 scopus 로고    scopus 로고
    • ASPP proteins specifically stimulate the apoptotic function of p53
    • Samuels-Lev Y, O'Connor DJ, Bergamaschi D, et al. ASPP proteins specifically stimulate the apoptotic function of p53. Mol Cell. 2001; 8: 781-94.
    • (2001) Mol Cell , vol.8 , pp. 781-794
    • Samuels-Lev, Y.1    O'Connor, D.J.2    Bergamaschi, D.3
  • 20
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 21
    • 9944240863 scopus 로고    scopus 로고
    • Splicing DNA-damage responses to tumour cell death
    • Crighton D, Ryan KM. Splicing DNA-damage responses to tumour cell death. Biochim Biophys Acta. 2004; 1705: 3-15.
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 3-15
    • Crighton, D.1    Ryan, K.M.2
  • 22
    • 0037220165 scopus 로고    scopus 로고
    • The UMD-p53 database: new mutations and analysis tools
    • Beroud C, Soussi T. The UMD-p53 database: new mutations and analysis tools. Hum Mutat. 2003; 21: 176-81.
    • (2003) Hum Mutat , vol.21 , pp. 176-181
    • Beroud, C.1    Soussi, T.2
  • 23
    • 79957994581 scopus 로고    scopus 로고
    • Mitochondrial dysfunction impairs tumor suppressor p53 expression/function
    • Compton S, Kim C, Griner NB, et al. Mitochondrial dysfunction impairs tumor suppressor p53 expression/function. J Biol Chem. 2011; 286: 20297-312.
    • (2011) J Biol Chem , vol.286 , pp. 20297-20312
    • Compton, S.1    Kim, C.2    Griner, N.B.3
  • 24
    • 0026669469 scopus 로고
    • p53 function and dysfunction
    • Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell. 1992; 70: 523-6.
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 26
    • 15244362062 scopus 로고    scopus 로고
    • P53 abnormalities and outcomes in colorectal cancer: a systematic review
    • Munro AJ, Lain S, Lane DP. P53 abnormalities and outcomes in colorectal cancer: a systematic review. Br J Cancer. 2005; 92: 434-44.
    • (2005) Br J Cancer , vol.92 , pp. 434-444
    • Munro, A.J.1    Lain, S.2    Lane, D.P.3
  • 28
    • 0033970863 scopus 로고    scopus 로고
    • Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines
    • Mori T, Okamoto H, Takahashi N, et al. Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines. FEBS Lett. 2000; 465: 124-8.
    • (2000) FEBS Lett , vol.465 , pp. 124-128
    • Mori, T.1    Okamoto, H.2    Takahashi, N.3
  • 29
    • 84883017889 scopus 로고    scopus 로고
    • Functions of autophagy in normal and diseased liver
    • Czaja MJ, Ding WX, Donohue TM Jr, et al. Functions of autophagy in normal and diseased liver. Autophagy. 2013; 9: 1131-58.
    • (2013) Autophagy , vol.9 , pp. 1131-1158
    • Czaja, M.J.1    Ding, W.X.2    Donohue Jr, T.M.3
  • 30
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: their role in cell survival and cell death
    • Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ. 2005; 12(Suppl 2): 1509-18.
    • (2005) Cell Death Differ , vol.12 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 31
    • 33745885329 scopus 로고    scopus 로고
    • DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
    • Crighton D, Wilkinson S, O'Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell. 2006; 126: 121-34.
    • (2006) Cell , vol.126 , pp. 121-134
    • Crighton, D.1    Wilkinson, S.2    O'Prey, J.3
  • 32
    • 15844394847 scopus 로고    scopus 로고
    • 53BP2 induces apoptosis through the mitochondrial death pathway
    • Kobayashi S, Kajino S, Takahashi N, et al. 53BP2 induces apoptosis through the mitochondrial death pathway. Genes Cells. 2005; 10: 253-60.
    • (2005) Genes Cells , vol.10 , pp. 253-260
    • Kobayashi, S.1    Kajino, S.2    Takahashi, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.