-
1
-
-
0032697488
-
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton
-
Fu CA, Shen M, Huang BC, Lasaga J, Payan DG, Luo Y. TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton. J Biol Chem 1999; 274: 30729-30737.
-
(1999)
J Biol Chem
, vol.274
, pp. 30729-30737
-
-
Fu, C.A.1
Shen, M.2
Huang, B.C.3
Lasaga, J.4
Payan, D.G.5
Luo, Y.6
-
2
-
-
10344249427
-
The Traf2-and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton
-
Taira K, Umikawa M, Takei K, Myagmar BE, Shinzato M, Machida N et al. The Traf2-and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton. J Biol Chem 2004; 279: 49488-49496.
-
(2004)
J Biol Chem
, vol.279
, pp. 49488-49496
-
-
Taira, K.1
Umikawa, M.2
Takei, K.3
Myagmar, B.E.4
Shinzato, M.5
Mac Hida, N.6
-
3
-
-
70350759551
-
The kinase TNIK is an essential activator of Wnt target genes
-
Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S et al. The kinase TNIK is an essential activator of Wnt target genes. EMBO J 2009; 28: 3329-3340.
-
(2009)
EMBO J
, vol.28
, pp. 3329-3340
-
-
Mahmoudi, T.1
Li, V.S.2
Ng, S.S.3
Taouatas, N.4
Vries, R.G.5
Mohammed, S.6
-
4
-
-
77953775569
-
Traf2-and Nckinteracting kinase is essential for Wnt signaling and colorectal cancer growth
-
Shitashige M, Satow R, Jigami T, Aoki K, Honda K, Shibata T et al. Traf2-and Nckinteracting kinase is essential for Wnt signaling and colorectal cancer growth. Cancer Res 2010; 70: 5024-5033.
-
(2010)
Cancer Res
, vol.70
, pp. 5024-5033
-
-
Shitashige, M.1
Satow, R.2
Jigami, T.3
Aoki, K.4
Honda, K.5
Shibata, T.6
-
6
-
-
84862207240
-
Three decades of Wnts: A personal perspective on how a scientific field developed
-
Nusse R, Varmus H. Three decades of Wnts: a personal perspective on how a scientific field developed. EMBO J 2012; 31: 2670-2684.
-
(2012)
EMBO J
, vol.31
, pp. 2670-2684
-
-
Nusse, R.1
Varmus, H.2
-
7
-
-
77954043663
-
Wnt signal transduction pathway and apoptosis: A review
-
Pecina-Slaus N. Wnt signal transduction pathway and apoptosis: a review. Cancer Cell Int 2010; 10: 22.
-
(2010)
Cancer Cell Int
, vol.10
, pp. 22
-
-
Pecina-Slaus, N.1
-
8
-
-
84873681862
-
The way Wnt works: Components and mechanism
-
Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A et al. The way Wnt works: components and mechanism. Growth Factors 2013; 31: 1-31.
-
(2013)
Growth Factors
, vol.31
, pp. 1-31
-
-
Saito-Diaz, K.1
Chen, T.W.2
Wang, X.3
Thorne, C.A.4
Wallace, H.A.5
Page-Mccaw, A.6
-
9
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas JN, Moon RT. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 2013; 13: 11-26.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
10
-
-
78049490305
-
MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function
-
Hussain NK, Hsin H, Huganir RL, Sheng M. MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function. J Neurosci 2010; 30: 14786-14794.
-
(2010)
J Neurosci
, vol.30
, pp. 14786-14794
-
-
Hussain, N.K.1
Hsin, H.2
Huganir, R.L.3
Sheng, M.4
-
11
-
-
75949126341
-
Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development
-
Kawabe H, Neeb A, Dimova K, Young Jr SM, Takeda M, Katsurabayashi S et al. Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron 2010; 65: 358-372.
-
(2010)
Neuron
, vol.65
, pp. 358-372
-
-
Kawabe, H.1
Neeb, A.2
Dimova, K.3
Young, S.M.4
Takeda, M.5
Katsurabayashi, S.6
-
12
-
-
84865734196
-
The germinal center kinase TNIK is required for canonical NF-kappaB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor
-
Shkoda A, Town JA, Griese J, Romio M, Sarioglu H, Knofel T et al. The germinal center kinase TNIK is required for canonical NF-kappaB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. PLoS Biol 2012; 10: e1001376.
-
(2012)
PLoS Biol
, vol.10
, pp. e1001376
-
-
Shkoda, A.1
Town, J.A.2
Griese, J.3
Romio, M.4
Sarioglu, H.5
Knofel, T.6
-
14
-
-
84879425949
-
Autophagy: Mechanisms, regulation, and its role in tumorigenesis
-
Parkhitko AA, Favorova OO, Henske EP. Autophagy: mechanisms, regulation, and its role in tumorigenesis. Biochemistry (Mosc) 2013; 78: 355-367.
-
(2013)
Biochemistry (Mosc)
, vol.78
, pp. 355-367
-
-
Parkhitko, A.A.1
Favorova, O.O.2
Henske, E.P.3
-
15
-
-
84884741607
-
The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patientderived gastric cancer xenograft model with PTEN loss to Taxotere
-
Li J, Davies BR, Han S, Zhou M, Bai Y, Zhang J et al. The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patientderived gastric cancer xenograft model with PTEN loss to Taxotere. J Transl Med 2013; 11: 241.
-
(2013)
J Transl Med
, vol.11
, pp. 241
-
-
Li, J.1
Davies, B.R.2
Han, S.3
Zhou, M.4
Bai, Y.5
Zhang, J.6
-
16
-
-
84871718156
-
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors
-
Ho KK, Parnell KM, Yuan Y, Xu Y, Kultgen SG, Hamblin S et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett 2013; 23: 569-573.
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 569-573
-
-
Ho, K.K.1
Parnell, K.M.2
Yuan, Y.3
Xu, Y.4
Kultgen, S.G.5
Hamblin, S.6
-
17
-
-
84877100340
-
FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547
-
Xie L, Su X, Zhang L, Yin X, Tang L, Zhang X et al. FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547. Clin Cancer Res 2013; 19: 2572-2583.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2572-2583
-
-
Xie, L.1
Su, X.2
Zhang, L.3
Yin, X.4
Tang, L.5
Zhang, X.6
|