Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells

Molecular Oncology

Volumn 9, Issue 3, 2015, Pages 617-627

  Park, Ji Hyun ^a   Szemes, Marianna ^a   Vieira, Gabriella Cunha ^a   Melegh, Zsombor ^b   Malik, Sally ^a   Heesom, Kate J ^a   Von Wallwitz Freitas, Laura ^a   Greenhough, Alexander ^c   Brown, Keith W ^a   Zheng, Y George ^d   Catchpoole, Daniel ^e   Deery, Michael J ^f   Malik, Karim ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d GEORGIA STATE UNIVERSITY   (United States)

^e CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Arginine methylation; MYCN; Neuroblastoma; PRMT5

Indexed keywords

CYCLOHEXIMIDE; MYCN PROTEIN; ONCOPROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN; PRMT5 PROTEIN, HUMAN; PROTEIN BINDING;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOPLASM; GENE AMPLIFICATION; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; AMINO ACID SEQUENCE; BRAIN TUMOR; CELL CYCLE; CHEMISTRY; GENE SILENCING; METABOLISM; MOLECULAR GENETICS; NEUROBLASTOMA; PATHOLOGY; PROTEIN STABILITY; TUMOR CELL LINE;

AMINO ACID SEQUENCE; APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HUMANS; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN-ARGININE N-METHYLTRANSFERASES;

EID: 84923353174     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.10.015     Document Type: Article

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