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Volumn 32, Issue 3, 2015, Pages

CCR9–CCL25 interaction suppresses apoptosis of lung cancer cells by activating the PI3K/Akt pathway

Author keywords

Apoptosis; CCL25; CCR9; NSCLC; PI3K Akt

Indexed keywords

BETA CHEMOKINE; CCL25 CHEMOKINE; CHEMOKINE RECEPTOR CCR9; LENTIVIRUS VECTOR; MOLECULAR MARKER; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; UNCLASSIFIED DRUG; WORTMANNIN; ANDROSTANE DERIVATIVE; CC CHEMOKINE RECEPTOR 9; CCL25 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR; ENZYME INHIBITOR;

EID: 84923328884     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-015-0531-0     Document Type: Article
Times cited : (39)

References (31)
  • 1
    • 84892805731 scopus 로고    scopus 로고
    • Cancer statistics, 2014
    • PID: 24399786
    • Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA. 2014;64(1):9–29.
    • (2014) CA , vol.64 , Issue.1 , pp. 9-29
    • Siegel, R.1    Ma, J.2    Zou, Z.3    Jemal, A.4
  • 2
    • 84901236222 scopus 로고    scopus 로고
    • Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention
    • PID: 24840047
    • Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K. Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention. Cancers. 2014;6(2):1157–79.
    • (2014) Cancers , vol.6 , Issue.2 , pp. 1157-1179
    • Kathuria, H.1    Gesthalter, Y.2    Spira, A.3    Brody, J.S.4    Steiling, K.5
  • 3
    • 84923358063 scopus 로고    scopus 로고
    • Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment
    • COI: 1:CAS:528:DC%2BC2cXhs12qsLg%3D, PID: 25342981
    • Cheng H, Shcherba M, Pendurti G, Liang Y, Piperdi B, Perez-Soler R. Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment. Lung Cancer Manag. 2014;3(1):67–75.
    • (2014) Lung Cancer Manag , vol.3 , Issue.1 , pp. 67-75
    • Cheng, H.1    Shcherba, M.2    Pendurti, G.3    Liang, Y.4    Piperdi, B.5    Perez-Soler, R.6
  • 5
    • 84903891089 scopus 로고    scopus 로고
    • Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer
    • COI: 1:CAS:528:DC%2BC2cXpslajtrw%3D, PID: 24863259
    • Fumarola C, Bonelli MA, Petronini PG, Alfieri RR. Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer. Biochem Pharmacol. 2014;90(3):197–207.
    • (2014) Biochem Pharmacol , vol.90 , Issue.3 , pp. 197-207
    • Fumarola, C.1    Bonelli, M.A.2    Petronini, P.G.3    Alfieri, R.R.4
  • 6
    • 78651331395 scopus 로고    scopus 로고
    • New prospects for chemokines
    • COI: 1:CAS:528:DC%2BC3MXjsFCju7k%3D, PID: 21215243
    • Rostene W. New prospects for chemokines. Biologie aujourd’hui. 2010;204(4):267–72.
    • (2010) Biologie aujourd’hui , vol.204 , Issue.4 , pp. 267-272
    • Rostene, W.1
  • 7
    • 29644440329 scopus 로고    scopus 로고
    • Premature expression of chemokine receptor CCR9 impairs T cell development
    • COI: 1:CAS:528:DC%2BD2MXhtlagtLvK, PID: 16365398
    • Uehara S, Hayes SM, Li L, El-Khoury D, Canelles M, Fowlkes BJ, Love PE. Premature expression of chemokine receptor CCR9 impairs T cell development. J Immunol. 2006;176(1):75–84.
    • (2006) J Immunol , vol.176 , Issue.1 , pp. 75-84
    • Uehara, S.1    Hayes, S.M.2    Li, L.3    El-Khoury, D.4    Canelles, M.5    Fowlkes, B.J.6    Love, P.E.7
  • 8
    • 84891029287 scopus 로고    scopus 로고
    • Paracrine activation of chemokine receptor CCR9 enhances the invasiveness of pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BC3sXhvFSqtLfP, PID: 23371851
    • Heinrich EL, Arrington AK, Ko ME, Luu C, Lee W, Lu J, Kim J. Paracrine activation of chemokine receptor CCR9 enhances the invasiveness of pancreatic cancer cells. Cancer Microenviron. 2013;6(3):241–5.
    • (2013) Cancer Microenviron , vol.6 , Issue.3 , pp. 241-245
    • Heinrich, E.L.1    Arrington, A.K.2    Ko, M.E.3    Luu, C.4    Lee, W.5    Lu, J.6    Kim, J.7
  • 9
    • 77955264994 scopus 로고    scopus 로고
    • CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion
    • PID: 20565782
    • Johnson EL, Singh R, Johnson-Holiday CM, Grizzle WE, Partridge EE, Lillard JW Jr, Singh S. CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion. J Ovarian Res. 2010;3:15.
    • (2010) J Ovarian Res , vol.3 , pp. 15
    • Johnson, E.L.1    Singh, R.2    Johnson-Holiday, C.M.3    Grizzle, W.E.4    Partridge, E.E.5    Lillard, J.W.6    Singh, S.7
  • 10
    • 79955492062 scopus 로고    scopus 로고
    • CCR9–CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion
    • PID: 21539750
    • Johnson-Holiday C, Singh R, Johnson EL, Grizzle WE, Lillard JW Jr, Singh S. CCR9–CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion. World J Surg Oncol. 2011;9:46.
    • (2011) World J Surg Oncol , vol.9 , pp. 46
    • Johnson-Holiday, C.1    Singh, R.2    Johnson, E.L.3    Grizzle, W.E.4    Lillard, J.W.5    Singh, S.6
  • 11
    • 77956633638 scopus 로고    scopus 로고
    • CCR9 mediates PI3K/AKT-dependent antiapoptotic signals in prostate cancer cells and inhibition of CCR9–CCL25 interaction enhances the cytotoxic effects of etoposide
    • COI: 1:CAS:528:DC%2BC3cXhtFSisrjJ
    • Sharma PK, Singh R, Novakovic KR, Eaton JW, Grizzle WE, Singh S. CCR9 mediates PI3K/AKT-dependent antiapoptotic signals in prostate cancer cells and inhibition of CCR9–CCL25 interaction enhances the cytotoxic effects of etoposide. Int J Cancer J. 2010;127(9):2020–30.
    • (2010) Int J Cancer J , vol.127 , Issue.9 , pp. 2020-2030
    • Sharma, P.K.1    Singh, R.2    Novakovic, K.R.3    Eaton, J.W.4    Grizzle, W.E.5    Singh, S.6
  • 12
    • 84908135144 scopus 로고    scopus 로고
    • CCR9 as a prognostic marker and therapeutic target in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2cXptlyqt7c%3D, PID: 24481516
    • Zhang Z, Qin C, Wu Y, Su Z, Xian G, Hu B. CCR9 as a prognostic marker and therapeutic target in hepatocellular carcinoma. Oncol Rep. 2014;31(4):1629–36.
    • (2014) Oncol Rep , vol.31 , Issue.4 , pp. 1629-1636
    • Zhang, Z.1    Qin, C.2    Wu, Y.3    Su, Z.4    Xian, G.5    Hu, B.6
  • 13
    • 84923376873 scopus 로고    scopus 로고
    • CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis
    • PID: 25296976
    • Gupta P, Sharma PK, Mir H, Singh R, Singh N, Kloecker GH, Lillard JW Jr, Singh S. CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis. Oncotarget. 2014;5(20):10170–9.
    • (2014) Oncotarget , vol.5 , Issue.20 , pp. 10170-10179
    • Gupta, P.1    Sharma, P.K.2    Mir, H.3    Singh, R.4    Singh, N.5    Kloecker, G.H.6    Lillard, J.W.7    Singh, S.8
  • 14
    • 84871601161 scopus 로고    scopus 로고
    • Chemokine receptor 9 high-expression involved in the migration and invasion of the non-small-cell lung cancer cells
    • COI: 1:CAS:528:DC%2BC3MXktl2nsrY%3D
    • Fan JA, Zhang L, Wang QL, Lin H. Chemokine receptor 9 high-expression involved in the migration and invasion of the non-small-cell lung cancer cells. Asian Biomed. 2011;5(1):69–76.
    • (2011) Asian Biomed , vol.5 , Issue.1 , pp. 69-76
    • Fan, J.A.1    Zhang, L.2    Wang, Q.L.3    Lin, H.4
  • 15
    • 84890909335 scopus 로고    scopus 로고
    • Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
    • COI: 1:CAS:528:DC%2BC3sXhvFOjsbvI, PID: 24355989
    • Czabotar PE, Lessene G, Strasser A, Adams JM. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy. Nat Rev Mol Cell Biol. 2014;15(1):49–63.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , Issue.1 , pp. 49-63
    • Czabotar, P.E.1    Lessene, G.2    Strasser, A.3    Adams, J.M.4
  • 16
    • 84881553676 scopus 로고    scopus 로고
    • Reactivation of AKT signaling following treatment of cancer cells with PI3K inhibitors attenuates their antitumor effects
    • COI: 1:CAS:528:DC%2BC3sXht1WrsL3P, PID: 23867821
    • Dufour M, Dormond-Meuwly A, Pythoud C, Demartines N, Dormond O. Reactivation of AKT signaling following treatment of cancer cells with PI3K inhibitors attenuates their antitumor effects. Biochem Biophys Res Commun. 2013;438(1):32–7.
    • (2013) Biochem Biophys Res Commun , vol.438 , Issue.1 , pp. 32-37
    • Dufour, M.1    Dormond-Meuwly, A.2    Pythoud, C.3    Demartines, N.4    Dormond, O.5
  • 17
    • 84868114011 scopus 로고    scopus 로고
    • Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer
    • COI: 1:CAS:528:DC%2BC38Xhs12qsrbP, PID: 23144692
    • Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Suzuki T, Okada Y, et al. Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer. PLoS One. 2012;7(10):e44368.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. 44368
    • Kuzumaki, N.1    Suzuki, A.2    Narita, M.3    Hosoya, T.4    Nagasawa, A.5    Imai, S.6    Yamamizu, K.7    Morita, H.8    Suzuki, T.9    Okada, Y.10
  • 19
    • 84920264191 scopus 로고    scopus 로고
    • The dichotomy of the insulin-like growth factor 1 receptor: RTK and GPCR: Friend or foe for cancer treatment?
    • COI: 1:CAS:528:DC%2BC2cXhvVGksr%2FP, PID: 25466906
    • Crudden C, Ilic M, Suleymanova N, Worrall C, Girnita A, Girnita L. The dichotomy of the insulin-like growth factor 1 receptor: RTK and GPCR: Friend or foe for cancer treatment? Growth Horm IGF Res. 2015;25(1):2–12.
    • (2015) Growth Horm IGF Res , vol.25 , Issue.1 , pp. 2-12
    • Crudden, C.1    Ilic, M.2    Suleymanova, N.3    Worrall, C.4    Girnita, A.5    Girnita, L.6
  • 20
    • 84893582726 scopus 로고    scopus 로고
    • Circulating human rotavirus specific CD4 T cells identified with a class II tetramer express the intestinal homing receptors alpha4beta7 and CCR9
    • PID: 24606696
    • Parra M, Herrera D, Calvo-Calle JM, Stern LJ, Parra-Lopez CA, Butcher E, Franco M, Angel J. Circulating human rotavirus specific CD4 T cells identified with a class II tetramer express the intestinal homing receptors alpha4beta7 and CCR9. Virology. 2014;452–453:191–201.
    • (2014) Virology , vol.452-453 , pp. 191-201
    • Parra, M.1    Herrera, D.2    Calvo-Calle, J.M.3    Stern, L.J.4    Parra-Lopez, C.A.5    Butcher, E.6    Franco, M.7    Angel, J.8
  • 21
    • 84883273810 scopus 로고    scopus 로고
    • Characterization of the CCR3 and CCR9 genes in miiuy croaker and different selection pressures imposed on different domains between mammals and teleosts
    • COI: 1:CAS:528:DC%2BC3sXhsFGjs7%2FI, PID: 23817141
    • Zhu Z, Wang R, Ren L, Xu T. Characterization of the CCR3 and CCR9 genes in miiuy croaker and different selection pressures imposed on different domains between mammals and teleosts. Dev Comp Immunol. 2013;41(4):631–43.
    • (2013) Dev Comp Immunol , vol.41 , Issue.4 , pp. 631-643
    • Zhu, Z.1    Wang, R.2    Ren, L.3    Xu, T.4
  • 24
    • 0035883065 scopus 로고    scopus 로고
    • Blocking of c-FLIP(L)—independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction
    • COI: 1:CAS:528:DC%2BD3MXmtFeisrc%3D, PID: 11493434
    • Youn BS, Kim YJ, Mantel C, Yu KY, Broxmeyer HE. Blocking of c-FLIP(L)—independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction. Blood. 2001;98(4):925–33.
    • (2001) Blood , vol.98 , Issue.4 , pp. 925-933
    • Youn, B.S.1    Kim, Y.J.2    Mantel, C.3    Yu, K.Y.4    Broxmeyer, H.E.5
  • 25
    • 84891913705 scopus 로고    scopus 로고
    • Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway
    • COI: 1:CAS:528:DC%2BC2cXptl2itbs%3D, PID: 24247158
    • Peng SF, Lee CY, Hour MJ, Tsai SC, Kuo DH, Chen FA, Shieh PC, Yang JS. Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway. Int J Oncol. 2014;44(1):238–46.
    • (2014) Int J Oncol , vol.44 , Issue.1 , pp. 238-246
    • Peng, S.F.1    Lee, C.Y.2    Hour, M.J.3    Tsai, S.C.4    Kuo, D.H.5    Chen, F.A.6    Shieh, P.C.7    Yang, J.S.8
  • 26
    • 84877765373 scopus 로고    scopus 로고
    • Regional imbalanced activation of the calcineurin/BAD apoptotic pathway and the PI3K/Akt survival pathway after myocardial infarction
    • PID: 22088220
    • Li T, Kilic A, Wei X, Wu C, Schwartzbauer G, Yankey GK, DeFilippi C, Bond M, Wu ZJ, Griffith BP. Regional imbalanced activation of the calcineurin/BAD apoptotic pathway and the PI3K/Akt survival pathway after myocardial infarction. Int J Cardiol. 2013;166(1):158–65.
    • (2013) Int J Cardiol , vol.166 , Issue.1 , pp. 158-165
    • Li, T.1    Kilic, A.2    Wei, X.3    Wu, C.4    Schwartzbauer, G.5    Yankey, G.K.6    DeFilippi, C.7    Bond, M.8    Wu, Z.J.9    Griffith, B.P.10
  • 27
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • COI: 1:CAS:528:DC%2BD2MXlt1eqtLo%3D, PID: 15784165
    • Song G, Ouyang G, Bao S. The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med. 2005;9(1):59–71.
    • (2005) J Cell Mol Med , vol.9 , Issue.1 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 28
    • 84928596564 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR signaling pathway as a therapeutic target for ovarian cancer
    • COI: 1:CAS:528:DC%2BC2cXht1Gqt7zL, PID: 25086744
    • Li H, Zeng J, Shen K. PI3K/AKT/mTOR signaling pathway as a therapeutic target for ovarian cancer. Arch Gynecol Obstet. 2014;290(6):1067–78.
    • (2014) Arch Gynecol Obstet , vol.290 , Issue.6 , pp. 1067-1078
    • Li, H.1    Zeng, J.2    Shen, K.3
  • 29
    • 84907063686 scopus 로고    scopus 로고
    • PI3K/AKT signaling pathway and cancer: an updated review
    • COI: 1:CAS:528:DC%2BC2cXhsFChurfK, PID: 24897931
    • Martini M, De Santis MC, Braccini L, Gulluni F, Hirsch E. PI3K/AKT signaling pathway and cancer: an updated review. Ann Med. 2014;46(6):372–83.
    • (2014) Ann Med , vol.46 , Issue.6 , pp. 372-383
    • Martini, M.1    De Santis, M.C.2    Braccini, L.3    Gulluni, F.4    Hirsch, E.5
  • 30
    • 33751201263 scopus 로고    scopus 로고
    • Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function
    • PID: 17083736
    • Nilsen J, Chen S, Irwin RW, Iwamoto S, Brinton RD. Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function. BMC Neurosci. 2006;7:74.
    • (2006) BMC Neurosci , vol.7 , pp. 74
    • Nilsen, J.1    Chen, S.2    Irwin, R.W.3    Iwamoto, S.4    Brinton, R.D.5
  • 31
    • 77950519173 scopus 로고    scopus 로고
    • Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells
    • COI: 1:CAS:528:DC%2BC3cXks1Kis70%3D, PID: 20214883
    • Peng DJ, Wang J, Zhou JY, Wu GS. Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells. Biochem Biophys Res Commun. 2010;394(3):600–5.
    • (2010) Biochem Biophys Res Commun , vol.394 , Issue.3 , pp. 600-605
    • Peng, D.J.1    Wang, J.2    Zhou, J.Y.3    Wu, G.S.4


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