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Volumn 5, Issue , 2014, Pages

NF-κB-induced KIAA1199 promotes survival through EGFR signalling

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KIAA1199 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; ONCOPROTEIN; PLEXIN; PROTEIN BCL 3; PROTEIN TYROSINE KINASE; SEMAPHORIN 3A; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; KIAA1199 PROTEIN, HUMAN; PROTEIN; PROTO-ONCOGENE PROTEIN BCL-3; SEMA3A PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA;

EID: 84923320522     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6232     Document Type: Article
Times cited : (102)

References (70)
  • 1
    • 54949147176 scopus 로고    scopus 로고
    • New regulators of NF-kappaB in inflammation
    • Ghosh, S. & Hayden, M. S. New regulators of NF-kappaB in inflammation. Nat. Rev. Immunol. 8, 837-848 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 837-848
    • Ghosh, S.1    Hayden, M.S.2
  • 2
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of NF-kappaB subunits in cancer
    • Perkins, N. D. The diverse and complex roles of NF-kappaB subunits in cancer. Nat. Rev. Cancer 12, 121-132 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 3
    • 0033539885 scopus 로고    scopus 로고
    • Increased expression of p50-NF-kappa B and constitutive activation of NF-kappa B transcription factors during mouse skin carcinogenesis
    • Budunova, I. V. et al. Increased expression of p50-NF-kappa B and constitutive activation of NF-kappa B transcription factors during mouse skin carcinogenesis. Oncogene 18, 7423-7431 (1999).
    • (1999) Oncogene , vol.18 , pp. 7423-7431
    • Budunova, I.V.1
  • 4
    • 0033565217 scopus 로고    scopus 로고
    • Expression of a dominant-negative mutant inhibitor-kappa B alpha of nuclear factor-kappa B in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo
    • Van Waes, C. et al. Expression of a dominant-negative mutant inhibitor-kappa B alpha of nuclear factor-kappa B in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo. Cancer Res. 59, 3468-3474 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 3468-3474
    • Van Waes, C.1
  • 5
    • 4644313276 scopus 로고    scopus 로고
    • Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma
    • Van Waes, C. et al. Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Res. 64, 6511-6523 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 6511-6523
    • Van Waes, C.1
  • 6
    • 0032477945 scopus 로고    scopus 로고
    • Alterations in NF-kappa B function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappa B
    • Khavari, P. A., Seitz, C. S., Lin, Q. & Deng, H. Alterations in NF-kappa B function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappa B. Proc. Natl Acad. Sci. USA 95, 2307-2312 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 2307-2312
    • Khavari, P.A.1    Seitz, C.S.2    Lin, Q.3    Deng, H.4
  • 7
    • 33746637977 scopus 로고    scopus 로고
    • Upregulation of nuclear factor-kappaB (NF-kappaB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer
    • Branca, M. et al. Upregulation of nuclear factor-kappaB (NF-kappaB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer. Diagn. Cytopathol. 34, 555-563 (2006).
    • (2006) Diagn. Cytopathol. , vol.34 , pp. 555-563
    • Branca, M.1
  • 8
    • 0037426670 scopus 로고    scopus 로고
    • NF-kappaB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix
    • Nair, A., Venkatraman, M., Maliekal, T. T., Nair, B. & Karunagaran, D. NF-kappaB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix. Oncogene 22, 50-58 (2003).
    • (2003) Oncogene , vol.22 , pp. 50-58
    • Nair, A.1    Venkatraman, M.2    Maliekal, T.T.3    Nair, B.4    Karunagaran, D.5
  • 9
    • 17244367193 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor-kB: Preferntial homodimerization of p50 subunits in cervical carcinoma
    • Prusty, B. K., Husain, S. A. & Das, B. C. Constitutive activation of nuclear factor-kB: preferntial homodimerization of p50 subunits in cervical carcinoma. Front. Biosci. 10, 1510-1519 (2005).
    • (2005) Front. Biosci. , vol.10 , pp. 1510-1519
    • Prusty, B.K.1    Husain, S.A.2    Das, B.C.3
  • 10
    • 73349106810 scopus 로고    scopus 로고
    • Association of constitutive nuclear factor-kappaB activation with aggressive aspects and poor prognosis in cervical cancer
    • Li, J. et al. Association of constitutive nuclear factor-kappaB activation with aggressive aspects and poor prognosis in cervical cancer. Int. J. Gynecol. Cancer 19, 1421-1426 (2009).
    • (2009) Int. J. Gynecol. Cancer , vol.19 , pp. 1421-1426
    • Li, J.1
  • 11
    • 0023232550 scopus 로고
    • Causes and management of cervical intraepithelial neoplasia
    • Richart, R. M. Causes and management of cervical intraepithelial neoplasia. Cancer 60(8 Suppl): 1951-1959 (1987).
    • (1987) Cancer , vol.60 , Issue.8 , pp. 1951-1959
    • Richart, R.M.1
  • 12
    • 0030577120 scopus 로고    scopus 로고
    • Papillomavirus infections-A major cause of human cancers
    • zur Hausen, H. Papillomavirus infections-a major cause of human cancers. Biochim. Biophys. Acta 1288, F55-F78 (1996).
    • (1996) Biochim. Biophys. Acta , vol.1288 , pp. F55-F78
    • Zur Hausen, H.1
  • 13
    • 80052286626 scopus 로고    scopus 로고
    • NF-kappaB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis
    • Hussain, I. et al. NF-kappaB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis. J. Virol. 85, 9013-9022 (2011).
    • (2011) J. Virol. , vol.85 , pp. 9013-9022
    • Hussain, I.1
  • 14
    • 33646727381 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner
    • James, M. A., Lee, J. H. & Klingelhutz, A. J. Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner. J. Virol. 80, 5301-5307 (2006).
    • (2006) J. Virol. , vol.80 , pp. 5301-5307
    • James, M.A.1    Lee, J.H.2    Klingelhutz, A.J.3
  • 15
    • 0035047160 scopus 로고    scopus 로고
    • Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NFkappaB-responsive genes in cervical keratinocytes
    • Nees, M. et al. Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NFkappaB-responsive genes in cervical keratinocytes. J. Virol. 75, 4283-4296 (2001).
    • (2001) J. Virol. , vol.75 , pp. 4283-4296
    • Nees, M.1
  • 16
    • 0036374920 scopus 로고    scopus 로고
    • Differential production of cytokines and activation of NF-kappaB in HPV-transformed keratinocytes
    • Havard, L., Delvenne, P., Frare, P., Boniver, J. & Giannini, S. L. Differential production of cytokines and activation of NF-kappaB in HPV-transformed keratinocytes. Virology 298, 271-285 (2002).
    • (2002) Virology , vol.298 , pp. 271-285
    • Havard, L.1    Delvenne, P.2    Frare, P.3    Boniver, J.4    Giannini, S.L.5
  • 17
    • 11344284490 scopus 로고    scopus 로고
    • High levels of p105 (NFKB1) and p100 (NFKB2) proteins in HPV16-transformed keratinocytes: Role of E6 and E7 oncoproteins
    • Havard, L., Rahmouni, S., Boniver, J. & Delvenne, P. High levels of p105 (NFKB1) and p100 (NFKB2) proteins in HPV16-transformed keratinocytes: role of E6 and E7 oncoproteins. Virology 331, 357-366 (2005).
    • (2005) Virology , vol.331 , pp. 357-366
    • Havard, L.1    Rahmouni, S.2    Boniver, J.3    Delvenne, P.4
  • 18
    • 0037067782 scopus 로고    scopus 로고
    • The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex
    • Spitkovsky, D., Hehner, S. P., Hofmann, T. G., Moller, A. & Schmitz, M. L. The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex. J. Biol. Chem. 277, 25576-25582 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 25576-25582
    • Spitkovsky, D.1    Hehner, S.P.2    Hofmann, T.G.3    Moller, A.4    Schmitz, M.L.5
  • 19
    • 0023595226 scopus 로고
    • Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia
    • McKeithan, T. W., Rowley, J. D., Shows, T. B. & Diaz, M. O. Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA 84, 9257-9260 (1987).
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 9257-9260
    • McKeithan, T.W.1    Rowley, J.D.2    Shows, T.B.3    Diaz, M.O.4
  • 20
    • 4944243782 scopus 로고    scopus 로고
    • GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity
    • Viatour, P. et al. GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity. Mol. Cell 16, 35-45 (2004).
    • (2004) Mol. Cell , vol.16 , pp. 35-45
    • Viatour, P.1
  • 21
    • 28844472948 scopus 로고    scopus 로고
    • Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas
    • Mathas, S. et al. Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas. Blood 106, 4287-4293 (2005).
    • (2005) Blood , vol.106 , pp. 4287-4293
    • Mathas, S.1
  • 22
    • 64249121404 scopus 로고    scopus 로고
    • High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis
    • Brenne, A. T. et al. High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis. Eur. J. Haematol. 82, 354-363 (2009).
    • (2009) Eur. J. Haematol. , vol.82 , pp. 354-363
    • Brenne, A.T.1
  • 23
    • 3342964254 scopus 로고    scopus 로고
    • Immunohistochemical detection of BCL-3 in lymphoid neoplasms: A survey of 353 cases
    • Canoz, O., Rassidakis, G. Z., Admirand, J. H. & Medeiros, L. J. Immunohistochemical detection of BCL-3 in lymphoid neoplasms: a survey of 353 cases. Mod. Pathol. 17, 911-917 (2004).
    • (2004) Mod. Pathol. , vol.17 , pp. 911-917
    • Canoz, O.1    Rassidakis, G.Z.2    Admirand, J.H.3    Medeiros, L.J.4
  • 24
    • 0038107396 scopus 로고    scopus 로고
    • High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease
    • Nishikori, M. et al. High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease. Blood 101, 2789-2796 (2003).
    • (2003) Blood , vol.101 , pp. 2789-2796
    • Nishikori, M.1
  • 25
    • 30944468153 scopus 로고    scopus 로고
    • Expression of the Bcl-3 protooncogene suppresses p53 activation
    • Kashatus, D., Cogswell, P. & Baldwin, A. S. Expression of the Bcl-3 protooncogene suppresses p53 activation. Genes Dev. 20, 225-235 (2006).
    • (2006) Genes Dev. , vol.20 , pp. 225-235
    • Kashatus, D.1    Cogswell, P.2    Baldwin, A.S.3
  • 26
    • 0034708132 scopus 로고    scopus 로고
    • Selective activation of NF-kappa B subunits in human breast cancer: Potential roles for NF-kappa B2/p52 and for Bcl-3
    • Cogswell, P. C., Guttridge, D. C., Funkhouser, W. K. & Baldwin, Jr. A. S. Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene 19, 1123-1131 (2000).
    • (2000) Oncogene , vol.19 , pp. 1123-1131
    • Cogswell, P.C.1    Guttridge, D.C.2    Funkhouser, W.K.3    Baldwin, A.S.4
  • 27
    • 37049004740 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas
    • O'Neil, B. H. et al. Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas. Oncology 72, 97-104 (2007).
    • (2007) Oncology , vol.72 , pp. 97-104
    • O'Neil, B.H.1
  • 28
    • 0346365370 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinoma
    • Thornburg, N. J., Pathmanathan, R. & Raab-Traub, N. Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinoma. Cancer Res. 63, 8293-8301 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 8293-8301
    • Thornburg, N.J.1    Pathmanathan, R.2    Raab-Traub, N.3
  • 29
    • 84884212418 scopus 로고    scopus 로고
    • Expression of Id proteins is regulated by the Bcl-3 proto-oncogene in prostate cancer
    • Ahlqvist, K., Saamarthy, K., Syed Khaja, A. S., Bjartell, A. & Massoumi, R. Expression of Id proteins is regulated by the Bcl-3 proto-oncogene in prostate cancer. Oncogene 32, 1601-1608 (2013).
    • (2013) Oncogene , vol.32 , pp. 1601-1608
    • Ahlqvist, K.1    Saamarthy, K.2    Syed Khaja, A.S.3    Bjartell, A.4    Massoumi, R.5
  • 30
    • 33646531810 scopus 로고    scopus 로고
    • Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling
    • Massoumi, R., Chmielarska, K., Hennecke, K., Pfeifer, A. & Fassler, R. Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell 125, 665-677 (2006).
    • (2006) Cell , vol.125 , pp. 665-677
    • Massoumi, R.1    Chmielarska, K.2    Hennecke, K.3    Pfeifer, A.4    Fassler, R.5
  • 31
    • 18844464056 scopus 로고    scopus 로고
    • Identification of the familial cylindromatosis tumoursuppressor gene
    • Bignell, G. R. et al. Identification of the familial cylindromatosis tumoursuppressor gene. Nat. Genet. 25, 160-165 (2000).
    • (2000) Nat. Genet. , vol.25 , pp. 160-165
    • Bignell, G.R.1
  • 32
    • 84886884401 scopus 로고    scopus 로고
    • Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration
    • Evensen, N. A. et al. Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration. J. Natl Cancer Inst. 105, 1402-1416 (2013).
    • (2013) J. Natl Cancer Inst. , vol.105 , pp. 1402-1416
    • Evensen, N.A.1
  • 33
    • 84880741104 scopus 로고    scopus 로고
    • Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors
    • Tiwari, A. et al. Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors. PLoS ONE 8, e69473 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e69473
    • Tiwari, A.1
  • 34
    • 80051583307 scopus 로고    scopus 로고
    • Repression of KIAA1199 attenuates Wntsignalling and decreases the proliferation of colon cancer cells
    • Birkenkamp-Demtroder, K. et al. Repression of KIAA1199 attenuates Wntsignalling and decreases the proliferation of colon cancer cells. Br. J. Cancer 105, 552-561 (2011).
    • (2011) Br. J. Cancer , vol.105 , pp. 552-561
    • Birkenkamp-Demtroder, K.1
  • 35
    • 37849013557 scopus 로고    scopus 로고
    • Transcriptome profile of human colorectal adenomas
    • Sabates-Bellver, J. et al. Transcriptome profile of human colorectal adenomas. Mol. Cancer Res. 5, 1263-1275 (2007).
    • (2007) Mol. Cancer Res. , vol.5 , pp. 1263-1275
    • Sabates-Bellver, J.1
  • 36
    • 67649185269 scopus 로고    scopus 로고
    • Clinicopathologic significance of KIAA1199 overexpression in human gastric cancer
    • Matsuzaki, S. et al. Clinicopathologic significance of KIAA1199 overexpression in human gastric cancer. Ann. Surg. Oncol. 16, 2042-2051 (2009).
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 2042-2051
    • Matsuzaki, S.1
  • 37
    • 84875847265 scopus 로고    scopus 로고
    • KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization
    • Yoshida, H. et al. KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization. Proc. Natl Acad. Sci. USA 110, 5612-5617 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 5612-5617
    • Yoshida, H.1
  • 38
    • 33745438660 scopus 로고    scopus 로고
    • Upregulation of the KIAA1199 gene is associated with cellular mortality
    • Michishita, E., Garces, G., Barrett, J. C. & Horikawa, I. Upregulation of the KIAA1199 gene is associated with cellular mortality. Cancer Lett. 239, 71-77 (2006).
    • (2006) Cancer Lett. , vol.239 , pp. 71-77
    • Michishita, E.1    Garces, G.2    Barrett, J.C.3    Horikawa, I.4
  • 39
    • 33744928116 scopus 로고    scopus 로고
    • Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappa B signaling
    • Dicker, A. P. et al. Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappa B signaling. Cancer Res. 66, 5209-5215 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 5209-5215
    • Dicker, A.P.1
  • 40
    • 77955478512 scopus 로고    scopus 로고
    • BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1
    • Keutgens, A. et al. BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1. J. Biol. Chem. 285, 25831-25840 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 25831-25840
    • Keutgens, A.1
  • 41
    • 54549103311 scopus 로고    scopus 로고
    • Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappa B activation
    • An, J. et al. Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappa B activation. Cancer Cell 14, 394-407 (2008).
    • (2008) Cancer Cell , vol.14 , pp. 394-407
    • An, J.1
  • 42
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus type-16 and type-18 promotes the degradation of P53
    • Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J. & Howley, P. M. The E6 oncoprotein encoded by human papillomavirus type-16 and type-18 promotes the degradation of P53. Cell 63, 1129-1136 (1990).
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 43
    • 0036851301 scopus 로고    scopus 로고
    • Protein-protein interactions between large proteins: Two-hybrid screening using a functionally classified library composed of long cDNAs
    • Nakayama, M., Kikuno, R. & Ohara, O. Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. Genome Res. 12, 1773-1784 (2002).
    • (2002) Genome Res. , vol.12 , pp. 1773-1784
    • Nakayama, M.1    Kikuno, R.2    Ohara, O.3
  • 44
    • 33748690757 scopus 로고    scopus 로고
    • G8: A novel domain associated with polycystic kidney disease and non-syndromic hearing loss
    • He, Q. Y. et al. G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss. Bioinformatics 22, 2189-2191 (2006).
    • (2006) Bioinformatics , vol.22 , pp. 2189-2191
    • He, Q.Y.1
  • 45
    • 47949102937 scopus 로고    scopus 로고
    • The semaphorins: Versatile regulators of tumour progression and tumour angiogenesis
    • Neufeld, G. & Kessler, O. The semaphorins: versatile regulators of tumour progression and tumour angiogenesis. Nat. Rev. Cancer 8, 632-645 (2008).
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 632-645
    • Neufeld, G.1    Kessler, O.2
  • 46
    • 54249115942 scopus 로고    scopus 로고
    • Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells
    • Castro-Rivera, E., Ran, S., Brekken, R. A. & Minna, J. D. Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells. Cancer Res. 68, 8295-8303 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 8295-8303
    • Castro-Rivera, E.1    Ran, S.2    Brekken, R.A.3    Minna, J.D.4
  • 47
    • 84865137629 scopus 로고    scopus 로고
    • Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer
    • Tamagnone, L. Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer. Cancer Cell 22, 145-152 (2012).
    • (2012) Cancer Cell , vol.22 , pp. 145-152
    • Tamagnone, L.1
  • 48
    • 77955286842 scopus 로고    scopus 로고
    • Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice
    • Casazza, A. et al. Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice. J. Clin. Invest. 120, 2684-2698 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 2684-2698
    • Casazza, A.1
  • 49
    • 50149105621 scopus 로고    scopus 로고
    • Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis
    • Yamaoka, T. et al. Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Proc. Natl Acad. Sci. USA 105, 11772-11777 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 11772-11777
    • Yamaoka, T.1
  • 50
    • 51049109014 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cervical cancer: Correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation
    • Lee, M. Y., Chou, C. Y., Tang, M. J. & Shen, M. R. Epithelial-mesenchymal transition in cervical cancer: correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation. Clin. Cancer Res. 14, 4743-4750 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4743-4750
    • Lee, M.Y.1    Chou, C.Y.2    Tang, M.J.3    Shen, M.R.4
  • 51
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani, S. A. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715 (2008).
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 52
    • 84866075905 scopus 로고    scopus 로고
    • Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancer
    • Kuscu, C. et al. Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancer. PLoS ONE 7, e44661 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e44661
    • Kuscu, C.1
  • 53
    • 0032568792 scopus 로고    scopus 로고
    • Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
    • Yamaoka, S. et al. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93, 1231-1240 (1998).
    • (1998) Cell , vol.93 , pp. 1231-1240
    • Yamaoka, S.1
  • 54
    • 0032541657 scopus 로고    scopus 로고
    • IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
    • Rothwarf, D. M., Zandi, E., Natoli, G. & Karin, M. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 395, 297-300 (1998).
    • (1998) Nature , vol.395 , pp. 297-300
    • Rothwarf, D.M.1    Zandi, E.2    Natoli, G.3    Karin, M.4
  • 55
    • 4344612243 scopus 로고    scopus 로고
    • NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
    • Huber, M. A. et al. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J. Clin. Invest. 114, 569-581 (2004).
    • (2004) J. Clin. Invest. , vol.114 , pp. 569-581
    • Huber, M.A.1
  • 56
    • 60549102324 scopus 로고    scopus 로고
    • Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma
    • Massoumi, R. et al. Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J. Exp. Med. 206, 221-232 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 221-232
    • Massoumi, R.1
  • 57
    • 0029806101 scopus 로고    scopus 로고
    • E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virustransfected keratinocytes
    • Wilding, J. et al. E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virustransfected keratinocytes. Cancer Res. 56, 5285-5292 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 5285-5292
    • Wilding, J.1
  • 58
    • 49349113654 scopus 로고    scopus 로고
    • Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes
    • Caberg, J. H. et al. Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes. Carcinogenesis 29, 1441-1447 (2008).
    • (2008) Carcinogenesis , vol.29 , pp. 1441-1447
    • Caberg, J.H.1
  • 59
    • 84875990922 scopus 로고    scopus 로고
    • The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species
    • Spangle, J. M. & Munger, K. The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species. PLoS Pathog. 9, e1003237 (2013).
    • (2013) PLoS Pathog. , vol.9 , pp. e1003237
    • Spangle, J.M.1    Munger, K.2
  • 60
    • 79952428584 scopus 로고    scopus 로고
    • Identification of potential biomarkers for early and advanced gastric adenocarcinoma detection
    • Chivu Economescu, M. et al. Identification of potential biomarkers for early and advanced gastric adenocarcinoma detection. Hepatogastroenterology 57, 1453-1464 (2010).
    • (2010) Hepatogastroenterology , vol.57 , pp. 1453-1464
    • Chivu Economescu, M.1
  • 61
    • 77955650050 scopus 로고    scopus 로고
    • The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1
    • Keutgens, A. et al. The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1. Mol. Cell. Biol. 30, 4006-4021 (2010).
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 4006-4021
    • Keutgens, A.1
  • 62
    • 0028187142 scopus 로고
    • Detection of human papillomaviruses in paraffin-embedded biopsies of cervical intraepithelial lesions-analysis by immunohistochemistry, in-situ hybridization, and the polymerase chain-reaction
    • Delvenne, P., Fontaine, M. A., Delvenne, C., Nikkels, A. & Boniver, J. Detection of human papillomaviruses in paraffin-embedded biopsies of cervical intraepithelial lesions-analysis by immunohistochemistry, in-situ hybridization, and the polymerase chain-reaction. Mod. Pathol. 7, 113-119 (1994).
    • (1994) Mod. Pathol. , vol.7 , pp. 113-119
    • Delvenne, P.1    Fontaine, M.A.2    Delvenne, C.3    Nikkels, A.4    Boniver, J.5
  • 63
    • 0030949357 scopus 로고    scopus 로고
    • PCR detection of human papillomavirus: Comparison between MY09/MY11 and GP5+/GP6+ primer systems
    • Qu, W. M. et al. PCR detection of human papillomavirus: comparison between MY09/MY11 and GP5+/GP6+ primer systems. J. Clin. Microbiol. 35, 1304-1310 (1997).
    • (1997) J. Clin. Microbiol. , vol.35 , pp. 1304-1310
    • Qu, W.M.1
  • 64
    • 0031057725 scopus 로고    scopus 로고
    • A general primer GP5+/GP6+-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings
    • Jacobs, M. V. et al. A general primer GP5+/GP6+-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings. J. Clin. Microbiol. 35, 791-795 (1997).
    • (1997) J. Clin. Microbiol. , vol.35 , pp. 791-795
    • Jacobs, M.V.1
  • 65
    • 79956195099 scopus 로고    scopus 로고
    • Biased amplification of human papillomavirus DNA in specimens containing multiple human papillomavirus types by PCR with consensus primers
    • Mori, S. et al. Biased amplification of human papillomavirus DNA in specimens containing multiple human papillomavirus types by PCR with consensus primers. Cancer Sci. 102, 1223-1227 (2011).
    • (2011) Cancer Sci. , vol.102 , pp. 1223-1227
    • Mori, S.1
  • 66
    • 2342466079 scopus 로고    scopus 로고
    • Application of physical force is essential to enrich for epidermal stem cells in primary human keratinocyte isolation
    • Park, H. S. et al. Application of physical force is essential to enrich for epidermal stem cells in primary human keratinocyte isolation. Tissue Eng. 10, 343-351 (2004).
    • (2004) Tissue Eng. , vol.10 , pp. 343-351
    • Park, H.S.1
  • 67
    • 21344449894 scopus 로고    scopus 로고
    • E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions
    • Hubert, P. et al. E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions. J. Pathol. 206, 346-355 (2005).
    • (2005) J. Pathol. , vol.206 , pp. 346-355
    • Hubert, P.1
  • 68
    • 78751627951 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor
    • Hanafusa, H. et al. Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor. Nat. Commun. 2, 158 (2011).
    • (2011) Nat. Commun. , vol.2 , pp. 158
    • Hanafusa, H.1
  • 69
    • 0026355160 scopus 로고
    • Dimerization of internalized epidermal growth factor receptors
    • Sorkin, A. & Carpenter, G. Dimerization of internalized epidermal growth factor receptors. J. Biol. Chem. 266, 23453-23460 (1991).
    • (1991) J. Biol. Chem. , vol.266 , pp. 23453-23460
    • Sorkin, A.1    Carpenter, G.2
  • 70
    • 84858077204 scopus 로고    scopus 로고
    • Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance
    • Lopez, J., Poitevin, A., Mendoza-Martinez, V., Perez-Plasencia, C. & Garcia-Carranca, A. Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance. BMC Cancer 12, 48 (2012).
    • (2012) BMC Cancer , vol.12 , pp. 48
    • Lopez, J.1    Poitevin, A.2    Mendoza-Martinez, V.3    Perez-Plasencia, C.4    Garcia-Carranca, A.5


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